Cardiac disease in pregnancy and arrhythmias
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Cafer Zorkun, M.D., Ph.D. [2]
Arrhythmias in Pregnancy
Although underlying reasons remain unclear, a significant increase of the incidence and severity of cardiac arrhythmias in pregnancy (particularly atrial and ventricular premature beats without an existing heart disease) have been reported in numerous articles, and these arrhythmias are usually benign. [1] [2] [3]
It is necessary to check if a pregnant woman takes any over the counter drug which causes palpitation or premature beats (e.g., pseudoephedrine). [3]
Anti-arrhythmic Drugs to Avoid During the Pregnancy
- Significant fetal abnormalities.
- Neonatal hypothyroidism
- Fetal goiter
- Fetal growth retardation
- Propranolol and atenolol[5] [6]:
- Intrauterine growth restriction
- Hypoglycemia in the newborn
Anti-arrhythmic Drugs to Avoid During Lactation
- Secreted in breast milk
- It becomes concentrated in breast milk. Infants receive much larger doses.
- Neonatal bradycardia
- Neonatal hypoglycemia
Related Chapters
References
- ↑ Tawam M, Levine J, Mendelson M, Goldberger J, Dyer A, Kadish A. Effect of pregnancy on paroxysmal supraventricular tachycardia. Am J Cardiol 1993; 72: 838-40.
- ↑ Brodsky M, Doria R, Allen B, Sato D, Thomas G, Sada M. New-onset ventricular tachycardia during pregnancy. Am Heart J 1992; 123: 933-41.
- ↑ 3.0 3.1 Chow T, Galvin J, McGovern B. Antiarrhythmic drug therapy in pregnancy and lactation. Am J Cardiol 1998; 82 (4A): 58I - 62I.
- ↑ 4.0 4.1 4.2 Onuigbo M, Alikhan M. Over-the-counter sympathomimetics: a risk factor for cardiac arrhythmias in pregnancy. South Med J 1998; 91: 1153-5.
- ↑ Eliahou HE, Silverberg DS, Reisin E, Romem I, Mashiach S, Serr DM. Propranolol for the treatment of hypertension in pregnancy. Br J Obstet Gynaecol 1978;85:431-6.
- ↑ Lydakis C, Lip GY, Beevers M, Beevers DG. Atenolol and fetal growth in pregnancies complicated by hypertension. Am J Hypertens 1999; 12:541-7.