Keratin 14

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keratin 14
Identifiers
Symbol KRT14
Alt. Symbols EBS3, EBS4
Entrez 3861
HUGO 6416
OMIM 148066
RefSeq NM_000526
UniProt P02533
Other data
Locus Chr. 17 q12-q21

Keratin 14 is a type I cytokeratin. It is usually found as a heterotetramer with two keratin 5 molecules, a type II keratin. Together they form the cytoskeleton of epithelial cells.

Pathology

Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex.


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