Tuberculosis differential diagnosis: Difference between revisions

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| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |Bacterial pneumonia
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |Bacterial pneumonia
| style="padding: 5px 5px; background: #F5F5F5;" | Sudden onset of symptoms, such as high [[fever]], [[cough]], [[purulent sputum]], [[chest pain]].  Consolidation on chest X-ray, [[leukocytosis]].
| style="padding: 5px 5px; background: #F5F5F5;" | Sudden onset of symptoms, such as high [[fever]], [[cough]], purulent [[sputum]], [[chest pain]].  Consolidation on chest X-ray, [[leukocytosis]].
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| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |Bronchogenic carcinoma
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |Bronchogenic carcinoma
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| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |Mycoplasmal pneumonia
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |Mycoplasmal pneumonia
| style="padding: 5px 5px; background: #F5F5F5;" |  
| style="padding: 5px 5px; background: #F5F5F5;" | Gradual onset of [[dry cough]], [[headache]], [[malaise]], [[sore throat]]. Diffuse bilateral infiltrates in chest X-ray.
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| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |Sarcoidosis  
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |Sarcoidosis  

Revision as of 20:02, 4 September 2014

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Alejandro Lemor, M.D. [2]

Overview

Pulmonary tuberculosis must be differentiated from other diseases that cause cough, fever, night sweats, hemoptysis and weight loss, such as: brucellosis, bronchogenic carcinoma, Hodgkin lymphoma, bacterial pneumonia, sarcoidosis, mycoplasmal pneumonia.

Differential Diagnosis

Pulmonary Tuberculosis

Disease Findings
Bacterial pneumonia Sudden onset of symptoms, such as high fever, cough, purulent sputum, chest pain. Consolidation on chest X-ray, leukocytosis.
Bronchogenic carcinoma Can be asymptomatic, usually at older ages (> 50 years old), cough, hemoptysis, weight loss
Brucellosis Fever, anorexia, night sweats, malaise,back pain , headache, and depression. History of exposure to infected animal
Hodgkin lymphoma Fever, night sweats, pruritus, painless adenopathy, mediastinal mass
Mycoplasmal pneumonia Gradual onset of dry cough, headache, malaise, sore throat. Diffuse bilateral infiltrates in chest X-ray.
Sarcoidosis Non-caseating granulomas in lungs and other organs, bilateral hiliar adenopathy, predominantly in African American females.

Extra-Pulmonary Tuberculosis

Extra-Pulmonary Location Differential Diagnosis
Tuberculous Lymphadenitis
Skeletal Tuberculosis
Central Nervous System Tuberculosis
Tuberculosis Peritonitis

References

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