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WikiDoc Resources for Depression


Most recent articles on Depression

Most cited articles on Depression

Review articles on Depression

Articles on Depression in N Eng J Med, Lancet, BMJ


Powerpoint slides on Depression

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Photos of Depression

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Evidence Based Medicine

Cochrane Collaboration on Depression

Bandolier on Depression

TRIP on Depression

Clinical Trials

Ongoing Trials on Depression at Clinical

Trial results on Depression

Clinical Trials on Depression at Google

Guidelines / Policies / Govt

US National Guidelines Clearinghouse on Depression

NICE Guidance on Depression


FDA on Depression

CDC on Depression


Books on Depression


Depression in the news

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Blogs on Depression


Definitions of Depression

Patient Resources / Community

Patient resources on Depression

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Patient Handouts on Depression

Directions to Hospitals Treating Depression

Risk calculators and risk factors for Depression

Healthcare Provider Resources

Symptoms of Depression

Causes & Risk Factors for Depression

Diagnostic studies for Depression

Treatment of Depression

Continuing Medical Education (CME)

CME Programs on Depression


Depression en Espanol

Depression en Francais


Depression in the Marketplace

Patents on Depression

Experimental / Informatics

List of terms related to Depression

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate-Editor-In-Chief: Christeen Henen, M.D.


Depression generally signifies a lowering or reduction of some kind, for example in the context of mood, economy, or functionality: is a mental disorder characterized by at least two weeks of low mood presenting in most situations.[1] It is often accompanied by low self-esteem, loss of interest, low energy, and pain without a clear cause.[1] People may also occasionally have false beliefs or see or hear things that others cannot.[1] Some people have periods of depression separated by years in which they are normal while others nearly always have symptoms present.[3] Major depressive disorder can negatively affect a person's personal, work, or school life, as well as sleeping, eating habits, and general health.[1][3] Between 2–7% of adults with major depression die by suicide,[2] and up to 60% of people who die by suicide had depression or another mood disorder.[6]


Psychology and mood
  • Depression (mood), a common term for a sad or low mood or emotional state, or the loss of pleasure.
  • Clinical depression, or major depressive disorder, a clinical term for a state of intense sadness, melancholia or despair that has advanced to the point of being disruptive to an individual's social functioning and/or activities of daily living. Subtypes of clinical depression:
  • Melancholic depression, characterized by the inability to find pleasure in positive things combined with physical agitation, insomnia, or decreased appetite.
  • Atypical depression, a common long term cyclical form of depression in which the individual can feel enjoyment, eat, and sleep, but there is significant lethargy, a 'leaden' feeling, and a strong response to rejection-related issues.
  • Psychotic depression, in which clinical depression co-exists with psychotic or delusional perceptions.
Other medical and biological uses
Other uses
  • Depression (geology), a sunken geological formation
  • Depression (economics), a longer-lasting and more severe economic downturn than a recession
  • The Great Depression, a severe economic recession in the 1930s
  • Depression (meteorology), an area of low atmospheric pressure associated with cyclones and weather fronts



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