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{{Spontaneous bacterial peritonitis}}
{{Spontaneous bacterial peritonitis}}
{{CMG}}; {{AE}} {{ADI}}
{{CMG}}; {{AE}}{{SCh}}; {{AY}}


==Overview==
==Overview==
Symptoms include fevers, chills, nausea, vomiting, abdominal tenderness and general malaise. Patients may complain of abdominal pain and worsening [[ascites]]. It is important to emphasize, though, that [[hepatic encephalopathy]] may be the ''only'' manifestation of SBP, especially in people with [[cirrhosis]] and [[ascites]].
The main manifestations of [[SBP]] are acute [[abdominal tenderness|abdominal pain]], [[abdominal tenderness|tenderness]], [[fever]]. Symptoms may be masked in the elderly and ~30% may be asymptomatic. Patients may also complain of worsening [[ascites]]. [[hepatic encephalopathy]] may be the ''only'' manifestation of SBP, especially in people with [[cirrhosis]] and [[ascites]]. The clinical presentation of SBP is highly variable as it may manifest as a relatively insidious colonization without signs and symptoms or it can rapidly develop as a [[Septicaemia|septic syndrome]].<ref name="HoefsRuyon1985">{{cite journal|last1=Hoefs|first1=John C.|last2=Ruyon|first2=B.A.|title=Spontaneous bacterial peritonis|journal=Disease-a-Month|volume=31|issue=9|year=1985|pages=1–48|issn=00115029|doi=10.1016/0011-5029(85)90002-1}}</ref>
==History==
A directed history should be obtained to ascertain the precipitant of this condition, detailed history has to be obtained regarding:
* Previous episodes of SBP.
 
* Associated conditions as [[portal Hypertension]], [[ cirrhosis]], [[ascites]], [[variceal bleeding]].
 
* Signs and symptoms of infection such as new-onset [[fever]] (greater than 37.8°C or 100°F), [[abdominal pain]], [[confusion]], [[hepatic encephalopathy]], [[metabolic acidosis]], [[renal failure]], [[hypotension]], [[diarrhea]], [[paralytic ileus]], [[hypothermia]], [[leukocytosis]] in a [[Cirrhosis|cirrhotic]] patient should prompt an evaluation of the [[Ascites|ascitic fluid]] for spontaneous bacterial peritonitis (SBP).
 
* Any [[renal disease]] and/or  [[heart disease]].
 
* Onset of symptoms and their progression.
 
* Hospitalizations, alcohol intake, [[hepatitis]].
 
* Invasive procedures, instrumentation including a history of [[Peritoneal dialysis]].  


==History==
* Presence of B-symptoms such as [[night sweats]], [[malaise]], [[weight loss]].
A directed history should be obtained to ascertain the precipitant of this condition. A detailed history has to be obtained regarding


* Previous episodes
* [[Immunodeficiency|Immune-deficiencies]] like [[HIV]].


* Associated conditions like [[diarrhea]], [[infections]]
* Use of [[Proton pump inhibitor|PPIs]] and [[beta-adrenergic antagonists]].


* History related to [[liver disease]], [[renal disease]] and [[heart disease]]
* Family history of [[liver disease]].


* Onset of symptoms and their progression
* History of [[respiratory]] and [[urinary tract infections]].


==Symptoms<ref>http://www.nlm.nih.gov/medlineplus/ency/article/000648.htm</ref> ==
==Common Symptoms ==
Some of the common symptoms of SBP include:<ref name="pmid9798013">{{cite journal| author=Such J, Runyon BA| title=Spontaneous bacterial peritonitis. | journal=Clin Infect Dis | year= 1998 | volume= 27 | issue= 4 | pages= 669-74; quiz 675-6 | pmid=9798013 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9798013  }} </ref><ref name="pmid23473819">{{cite journal| author=Chinnock B, Hendey GW, Minnigan H, Butler J, Afarian H| title=Clinical impression and ascites appearance do not rule out bacterial peritonitis. | journal=J Emerg Med | year= 2013 | volume= 44 | issue= 5 | pages= 903-9 | pmid=23473819 | doi=10.1016/j.jemermed.2012.07.086 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23473819  }} </ref>
* [[Fever]]<ref name="urlPeritonitis - spontaneous: MedlinePlus Medical Encyclopedia">{{cite web |url=http://www.nlm.nih.gov/medlineplus/ency/article/000648.htm |title=Peritonitis - spontaneous: MedlinePlus Medical Encyclopedia |format= |work= |accessdate=}}</ref>


* [[Fever]]
* Worsening of pre-existing [[ascites]] and progressive [[encephalopathy]] in a patient with [[Ascites|cirrhotic ascites]]


* [[Abdominal pain]]
* Diffuse, continuous [[abdominal pain]] may be present and few patients may be asymptomatic.


* [[Confusion]]
* [[Altered mental status]] may manifest as frank [[delirium]], [[confusion]] or cognitive slowing.


* [[Diarrhea]]
* [[Diarrhea]]


* Development of [[ileus|ileus paralyticus]] (i.e. intestinal paralysis), which also causes [[nausea]] and [[vomiting]]
== Less common symptoms of SBP ==
* [[Bloating]]
* [[Bloating]]


* [[Nausea]] and [[vomiting]]
* [[Anorexia]]
 
* [[Obstipation]]


* [[Joint pain]]
* [[Low urine output]]


* [[Breathlessness]] may be due to [[infection]], [[fluid overload]] or underlying [[heart condition]].
* Thirst


* [[Fatigue]]
* Chills
* [[Dizziness]] or weakness
* [[Breathlessness]] may be due to [[infection]], [[fluid overload]] or underlying heart condition
==References==
==References==
{{reflist|2}}
{{reflist|2}}


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Latest revision as of 00:15, 30 July 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shivani Chaparala M.B.B.S [2]; Ahmed Younes M.B.B.CH [3]

Overview

The main manifestations of SBP are acute abdominal pain, tenderness, fever. Symptoms may be masked in the elderly and ~30% may be asymptomatic. Patients may also complain of worsening ascites. hepatic encephalopathy may be the only manifestation of SBP, especially in people with cirrhosis and ascites. The clinical presentation of SBP is highly variable as it may manifest as a relatively insidious colonization without signs and symptoms or it can rapidly develop as a septic syndrome.[1]

History

A directed history should be obtained to ascertain the precipitant of this condition, detailed history has to be obtained regarding:

  • Previous episodes of SBP.
  • Onset of symptoms and their progression.

Common Symptoms

Some of the common symptoms of SBP include:[2][3]

  • Diffuse, continuous abdominal pain may be present and few patients may be asymptomatic.

Less common symptoms of SBP

  • Thirst
  • Chills

References

  1. Hoefs, John C.; Ruyon, B.A. (1985). "Spontaneous bacterial peritonis". Disease-a-Month. 31 (9): 1–48. doi:10.1016/0011-5029(85)90002-1. ISSN 0011-5029.
  2. Such J, Runyon BA (1998). "Spontaneous bacterial peritonitis". Clin Infect Dis. 27 (4): 669–74, quiz 675-6. PMID 9798013.
  3. Chinnock B, Hendey GW, Minnigan H, Butler J, Afarian H (2013). "Clinical impression and ascites appearance do not rule out bacterial peritonitis". J Emerg Med. 44 (5): 903–9. doi:10.1016/j.jemermed.2012.07.086. PMID 23473819.
  4. "Peritonitis - spontaneous: MedlinePlus Medical Encyclopedia".


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