Multiple endocrine neoplasia type 2 differential diagnosis: Difference between revisions
Line 16: | Line 16: | ||
| style="padding: 5px 5px; background: #F5F5F5;" |[[Medullary thyroid cancer]] (MTC) is a form of [[thyroid carcinoma]] which originates from the [[parafollicular cell]]s ([[C cell]]s), which produce the [[hormone]] [[calcitonin]]. | | style="padding: 5px 5px; background: #F5F5F5;" |[[Medullary thyroid cancer]] (MTC) is a form of [[thyroid carcinoma]] which originates from the [[parafollicular cell]]s ([[C cell]]s), which produce the [[hormone]] [[calcitonin]]. | ||
|- | |- | ||
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" | | | style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |C-cell hyperplasia | ||
| style="padding: 5px 5px; background: #F5F5F5;" |It is a genetic condition that causes proliferation of [[C cell]]s of [[parathyroid gland]]. | | style="padding: 5px 5px; background: #F5F5F5;" |It is a genetic condition that causes proliferation of [[C cell]]s of [[parathyroid gland]]. | ||
|- | |- | ||
Line 22: | Line 22: | ||
| style="padding: 5px 5px; background: #F5F5F5;" | A [[neuroendocrine tumor]] of the [[medulla]] of the [[adrenal gland]]s (originating in the [[chromaffin cell]]s), or extra-adrenal [[chromaffin]] [[tissue]] that failed to involute after birth. | | style="padding: 5px 5px; background: #F5F5F5;" | A [[neuroendocrine tumor]] of the [[medulla]] of the [[adrenal gland]]s (originating in the [[chromaffin cell]]s), or extra-adrenal [[chromaffin]] [[tissue]] that failed to involute after birth. | ||
|- | |- | ||
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |[[ | | style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |[[von Hippel Lindau syndrome]] | ||
| style="padding: 5px 5px; background: #F5F5F5;" |An [[autosomal dominant]] genetic disorder causing abnormal growth of [[blood vessel]]s in different parts of the [[body]]. | | style="padding: 5px 5px; background: #F5F5F5;" |An [[autosomal dominant]] genetic disorder causing abnormal growth of [[blood vessel]]s in different parts of the [[body]]. | ||
|- | |- | ||
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" | | | style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |Hereditary paraganglioma-pheochromocytoma syndrome | ||
| style="padding: 5px 5px; background: #F5F5F5;" |A genetic disorder causing abnormal growth of [[ganglion]]s along with [[tumor]] of the [[medulla]] of [[adrenal gland]]. | | style="padding: 5px 5px; background: #F5F5F5;" |A genetic disorder causing abnormal growth of [[ganglion]]s along with [[tumor]] of the [[medulla]] of [[adrenal gland]]. | ||
|- | |- | ||
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" | | | style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |Polycythemia and paraganglioma/pheochromocytoma | ||
| style="padding: 5px 5px; background: #F5F5F5;" |A genetic disorder causing abnormal growth of [[ganglion]]s and [[RBC cell]]s. | | style="padding: 5px 5px; background: #F5F5F5;" |A genetic disorder causing abnormal growth of [[ganglion]]s and [[RBC cell]]s. | ||
|- | |- |
Revision as of 13:05, 7 October 2015
Multiple endocrine neoplasia type 2 Microchapters |
Differentiating Multiple endocrine neoplasia type 2 from other Diseases |
---|
Diagnosis |
Treatment |
Multiple endocrine neoplasia type 2 differential diagnosis On the Web |
American Roentgen Ray Society Images of Multiple endocrine neoplasia type 2 differential diagnosis |
FDA on Multiple endocrine neoplasia type 2 differential diagnosis |
CDC on Multiple endocrine neoplasia type 2 differential diagnosis |
Multiple endocrine neoplasia type 2 differential diagnosis in the news |
Blogs on Multiple endocrine neoplasia type 2 differential diagnosis |
Directions to Hospitals Treating Multiple endocrine neoplasia type 2 |
Risk calculators and risk factors for Multiple endocrine neoplasia type 2 differential diagnosis |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]
Overview
Multiple endocrine neoplasia type 2 must be differentiated from other hereditary tumors such as medullary thyroid carcinoma, C-cell hyperplasia, pheochromocytoma, von Hippel Lindau syndrome, hereditary paraganglioma-pheochromocytoma, polycythemia and paraganglioma/pheochromocytoma syndrome, neurofibromatosis type 1, and multiple endocrine neoplasia type 1 (MEN 1).
Differentiating Multiple endocrine neoplasia type 2 from other Diseases
Multiple endocrine neoplasia type 2 must be differentiated from the following hereditary diseases.
Disease | Definition |
---|---|
Medullary thyroid carcinoma | Medullary thyroid cancer (MTC) is a form of thyroid carcinoma which originates from the parafollicular cells (C cells), which produce the hormone calcitonin. |
C-cell hyperplasia | It is a genetic condition that causes proliferation of C cells of parathyroid gland. |
Pheochromocytoma | A neuroendocrine tumor of the medulla of the adrenal glands (originating in the chromaffin cells), or extra-adrenal chromaffin tissue that failed to involute after birth. |
von Hippel Lindau syndrome | An autosomal dominant genetic disorder causing abnormal growth of blood vessels in different parts of the body. |
Hereditary paraganglioma-pheochromocytoma syndrome | A genetic disorder causing abnormal growth of ganglions along with tumor of the medulla of adrenal gland. |
Polycythemia and paraganglioma/pheochromocytoma | A genetic disorder causing abnormal growth of ganglions and RBC cells. |
Neurofibromatosis type 1 | Neurofibromatosis type I is a tumor disorder that is caused by the mutation of a gene on chromosome 17 that is responsible for control of cell division causing tumors along the nervous system. Common symptoms of neurofibromatosis type I include scoliosis (curvature of the spine), learning disabilities, vision disorders, and epilepsy. |
Multiple endocrine neoplasia type 1 (MEN 1) | An autosomal dominant genetic disorder causing tumors of parathyroid, pancreas, and pituitary gland. |
Adapted from Marquard J, Eng C. Multiple Endocrine Neoplasia Type 2. 1999 Sep 27 [Updated 2015 Jun 25]. In: Pagon RA, Adam MP, Ardinger HH, et al., editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2015. Available from: http://www.ncbi.nlm.nih.gov/books/NBK1257/[1] |
References
- ↑ Jessica Marquard & Charis Eng (1993). "Multiple Endocrine Neoplasia Type 2". PMID 020301434.