Mucormycosis physical examination

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Mucormycosis Microchapters

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Overview

Historical Perspective

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Pathophysiology

Causes

Differentiating Mucormycosis from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Criteria

History and Symptoms

Physical Examination

Laboratory Findings

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Treatment

Medical Therapy

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Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Syed Hassan A. Kazmi BSc, MD [2]

Overview

Patients with mucormycosis usually appear lethargic, weak and debilitated owing to its development in immune compromised patients. Physical examination of patients with mucorm ycosis is usually remarkable for skin necrosis with a black eschar, fever, chills, myalgias, sore throat, non-productive cough, abdominal pain.

Physical Examination

Appearence of the patient

  • Patients with mucormycosis usually appear weak and debilitated owing to its development in immune compromised individuals and patients with metabolic disorders.

Vital Signs

  • High-grade fever
  • Hypothermia/hyperthermia may be present in disseminated infection
  • Tachycardia
  • Tachypnea
  • Kussmal respirations may be present in diabetic patients who develop mucormycosis on a background of diabetic ketoacidosis
  • Weak pulse
  • Low blood pressure if condition leads to septic shock

Skin

  • Skin may show tissue necrosis

Nasal and palatal findings

  • Gray or erythematous appearance
  • Can progress to black necrotic masses (ie, black eschar)
  • Swelling

Ocular findings

  • Proptosis
  • Muddy sclera
  • Conjunctival chemosis
  • Ophthalmoplegia
  • Fixed pupil
  • Blindness
  • Nystagmus
  • Visual loss secondary to retinal artery thrombosis or direct fungal invasion

Neurologic findings

  • Palsies of cranial nerves II, III, IV, V, VI, and VII
  • Cerebral edema and vascular compromise may lead to coma and stroke

Pulmonary

  • Sore throat
  • Dyspnea on exertion
  • Non-productive cough
  • Crackles and rales on chest auscultation in pulmonary mucormycosis

GIT

  • Abdominal pain
  • Decreased bowel sounds

References

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