Interleukin-28
| Interleukin 28A | |
|---|---|
| Identifiers | |
| Symbol | IL28A |
| Alt. symbols | , IFNL2 |
| Entrez | 282616 |
| HUGO | 18364 |
| OMIM | 607401 |
| RefSeq | NM_172138 |
| UniProt | Q8IZJ0 |
| Other data | |
| Locus | Chr. 19 q13.13 |
| Interleukin 28B | |
|---|---|
| Identifiers | |
| Symbol | IL28B |
| Alt. symbols | , IFNL3 |
| Entrez | 282617 |
| HUGO | 18365 |
| OMIM | 607402 |
| RefSeq | NM_172139 |
| UniProt | Q8IZI9 |
| Other data | |
| Locus | Chr. 19 q13.13 |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Interleukin-28 (IL-28) is a cytokine that comes in two isoforms, IL-28A and IL-28B, and plays a role in immune defense against viruses.[1] IL-28A and IL-28B belong to the type III interferon family of cytokines and are highly similar (in amino acid sequence) to IL-29.
IL-28 genes are located near IL-29 on chromosome 19 in humans.
References
- ↑ D. Kempuraj et al., Interleukin-28 and 29 (IL-28 and IL-29): new cytokines with anti-viral activities. International Journal of Immunopathology and Pharmacology, 2004, Volume 17, pages 103-106.