De Quervain's thyroiditis history and symptoms: Difference between revisions
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==Overview== | ==Overview== | ||
The hallmark of [[de Quervain's thyroiditis]] is [[hyperthyroidism]] with the neck pain. A positive history of [[viral illness]] and family history of de Quervain's thyroiditis are suggestive of de Quervain's thyroiditis. The most common symptoms of de Quervain's thyroiditis are [[neck pain]], [[palpitations]], [[tachycardia]], [[nervousness]], and [[tremors | The hallmark of [[de Quervain's thyroiditis]] is [[hyperthyroidism]] with the neck pain. A positive history of [[viral illness]] and family history of de Quervain's thyroiditis are suggestive of de Quervain's thyroiditis. The most common symptoms of de Quervain's thyroiditis are [[neck pain]], [[palpitations]], [[tachycardia]], [[nervousness]], and [[tremors|tremors.]] | ||
== | == History and symptoms == | ||
===Hyperthyroidism(in acute phase)=== | === History === | ||
De Quervain's thyroiditis is usually preceded by a viral prodrome followed by the symptoms of thyrotoxicosis. This phase of thyrotoxicosis lasts for several weeks to few months. | Patients with [[de Quervain's thyroiditis]] usually have the history of [[viral]] [[illness]] and [[family history]] of [[de Quervain's thyroiditis]]. Patients may have the history of [[low-grade fever]] and viral flu-like symptoms, such as [[sore throat]], [[myalgia]], [[arthralgia]], and [[malaise]]. | ||
===Symptoms=== | |||
===Common Symptoms=== | |||
Common symptoms of de Quervain's thyroiditis include:<ref name="pmid25905408">{{cite journal |vauthors=De Groot LJ, Chrousos G, Dungan K, Feingold KR, Grossman A, Hershman JM, Koch C, Korbonits M, McLachlan R, New M, Purnell J, Rebar R, Singer F, Vinik A, Shrestha RT, Hennessey J |title= |journal= |volume= |issue= |pages= |year= |pmid=25905408 |doi= |url=}}</ref> | |||
*Symptoms of preceding [[upper respiratory infection]] | |||
**[[Malaise]] | |||
**[[Myalgia]] | |||
**[[Sore throat]] | |||
*[[Fever]] | |||
*Painful [[Thyroid mass causes|thyroid swelling]] | |||
*Symptoms of [[thyrotoxicosis]] | |||
**[[Tremors]] | |||
**[[Nervousness]] | |||
**[[Sweating]] | |||
===Symptoms according to the disease stage=== | |||
[[De Quervain's thyroiditis]] usually causes [[hyperthyroidism]] in its acute phase. However, it can also cause [[hypothyroidism]] in some cases.<ref name="urlThyroiditis — NEJM">{{cite web |url=http://www.nejm.org/doi/full/10.1056/NEJMra021194 |title=Thyroiditis — NEJM |format= |work= |accessdate=}}</ref><ref name="pmid12727961">{{cite journal |vauthors=Fatourechi V, Aniszewski JP, Fatourechi GZ, Atkinson EJ, Jacobsen SJ |title=Clinical features and outcome of subacute thyroiditis in an incidence cohort: Olmsted County, Minnesota, study |journal=J. Clin. Endocrinol. Metab. |volume=88 |issue=5 |pages=2100–5 |year=2003 |pmid=12727961 |doi=10.1210/jc.2002-021799 |url=}}</ref><ref name="pmid20886353">{{cite journal |vauthors=Engkakul P, Mahachoklertwattana P, Poomthavorn P |title=Eponym : de Quervain thyroiditis |journal=Eur. J. Pediatr. |volume=170 |issue=4 |pages=427–31 |year=2011 |pmid=20886353 |doi=10.1007/s00431-010-1306-4 |url=}}</ref><ref name="pmid2571803">{{cite journal |vauthors=Leibovitch G, Maaravi Y, Shalev O |title=Severe facial oedema and glossitis associated with mianserin |journal=Lancet |volume=2 |issue=8667 |pages=871–2 |year=1989 |pmid=2571803 |doi= |url=}}</ref> | |||
====Hyperthyroidism (in acute phase)==== | |||
[[De Quervain's thyroiditis]] is usually preceded by a [[viral]] [[prodrome]] followed by the symptoms of [[thyrotoxicosis]]. This phase of [[thyrotoxicosis]] lasts for several weeks to few months. | |||
====General==== | ====General==== | ||
The patient may have the following general symptoms: | The patient may have the following general symptoms: | ||
| Line 23: | Line 40: | ||
The patient may have: | The patient may have: | ||
*[[Neck pain|Severe neck pain]] | *[[Neck pain|Severe neck pain]] | ||
*Radiation of pain to the ears and/or jaw | *Radiation of pain to the [[ears]] and/or [[jaw]] | ||
*Neck swelling | *Neck [[swelling]] | ||
====Gastrointestinal system==== | ====Gastrointestinal system==== | ||
| Line 44: | Line 61: | ||
*[[Sweating]] | *[[Sweating]] | ||
===Hypothyroidism(in later stage)=== | ===Hypothyroidism (in later stage)=== | ||
The symptoms of [[hypothyroidism]] may develop in the later stages of de Quervain's thyroiditis during the recovery of thyrotoxicosis. This phase usually lasts for four to six months. Rarely, the residual hypothyroidism may persist. | * The symptoms of [[hypothyroidism]] may develop in the later stages of de Quervain's thyroiditis during the recovery of [[thyrotoxicosis]]. This phase usually lasts for four to six months. | ||
* Rarely, the residual [[hypothyroidism]] may persist. | |||
====General==== | ====General==== | ||
The patient may have: | The patient may have: | ||
| Line 62: | Line 81: | ||
*[[Dysphonia]] (from involvement of the [[recurrent laryngeal nerve]]) | *[[Dysphonia]] (from involvement of the [[recurrent laryngeal nerve]]) | ||
*[[Dyspnea]] (from the [[Tracheal compression|compression of the trachea]]) | *[[Dyspnea]] (from the [[Tracheal compression|compression of the trachea]]) | ||
*[[Dysphagia]] (from impingement upon the esophagus) | *[[Dysphagia]] (from impingement upon the [[esophagus]]) | ||
* Small or shrunken thyroid gland (late in the disease) | * Small or shrunken [[thyroid gland]] (late in the [[disease]]) | ||
====Gastrointestinal system==== | ====Gastrointestinal system==== | ||
| Line 81: | Line 100: | ||
====Reproductive system==== | ====Reproductive system==== | ||
The patient may have: | The patient may have: | ||
* [[Infertility]] | *[[Infertility]] | ||
*[[Oligomenorrhea]] | *[[Oligomenorrhea]] | ||
*[[Menometrorrhagia]] | *[[Menometrorrhagia]] | ||
| Line 91: | Line 110: | ||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
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[[Category:Medicine]] | |||
[[Category:Endocrinology]] | |||
[[Category:Up-To-Date]] | |||
Latest revision as of 21:14, 29 July 2020
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De Quervain's thyroiditis Microchapters |
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Differentiating De Quervain's thyroiditis from other Diseases |
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Diagnosis |
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Treatment |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Furqan M M. M.B.B.S[2]
Overview
The hallmark of de Quervain's thyroiditis is hyperthyroidism with the neck pain. A positive history of viral illness and family history of de Quervain's thyroiditis are suggestive of de Quervain's thyroiditis. The most common symptoms of de Quervain's thyroiditis are neck pain, palpitations, tachycardia, nervousness, and tremors.
History and symptoms
History
Patients with de Quervain's thyroiditis usually have the history of viral illness and family history of de Quervain's thyroiditis. Patients may have the history of low-grade fever and viral flu-like symptoms, such as sore throat, myalgia, arthralgia, and malaise.
Symptoms
Common Symptoms
Common symptoms of de Quervain's thyroiditis include:[1]
- Symptoms of preceding upper respiratory infection
- Fever
- Painful thyroid swelling
- Symptoms of thyrotoxicosis
Symptoms according to the disease stage
De Quervain's thyroiditis usually causes hyperthyroidism in its acute phase. However, it can also cause hypothyroidism in some cases.[2][3][4][5]
Hyperthyroidism (in acute phase)
De Quervain's thyroiditis is usually preceded by a viral prodrome followed by the symptoms of thyrotoxicosis. This phase of thyrotoxicosis lasts for several weeks to few months.
General
The patient may have the following general symptoms:
Localized
The patient may have:
- Severe neck pain
- Radiation of pain to the ears and/or jaw
- Neck swelling
Gastrointestinal system
The patient may have:
Cardiovascular system
The patient may have:
Neuro-psychiatric system
The patient may have:
Skin and appendages
The patient may have:
Hypothyroidism (in later stage)
- The symptoms of hypothyroidism may develop in the later stages of de Quervain's thyroiditis during the recovery of thyrotoxicosis. This phase usually lasts for four to six months.
- Rarely, the residual hypothyroidism may persist.
General
The patient may have:
- Fatigue
- Lethargy
- Cold intolerance
- Myxedema
- Weight gain
- Weight loss
- Migraines
- Puffy face
Localized symptoms
The patient may have:
- Enlarged neck or presence of goiter
- Dysphonia (from involvement of the recurrent laryngeal nerve)
- Dyspnea (from the compression of the trachea)
- Dysphagia (from impingement upon the esophagus)
- Small or shrunken thyroid gland (late in the disease)
Gastrointestinal system
The patient may have:
Skin and appendages
The patient may have:
Neuro-psychiatric system
The patient may have:
- Depression
- Difficulty concentrating or thinking
- Mania
- Memory loss
- Panic attacks
Reproductive system
The patient may have:
Musculoskeletal
The patient may have:
References
- ↑ De Groot LJ, Chrousos G, Dungan K, Feingold KR, Grossman A, Hershman JM, Koch C, Korbonits M, McLachlan R, New M, Purnell J, Rebar R, Singer F, Vinik A, Shrestha RT, Hennessey J. PMID 25905408. Missing or empty
|title=(help) - ↑ "Thyroiditis — NEJM".
- ↑ Fatourechi V, Aniszewski JP, Fatourechi GZ, Atkinson EJ, Jacobsen SJ (2003). "Clinical features and outcome of subacute thyroiditis in an incidence cohort: Olmsted County, Minnesota, study". J. Clin. Endocrinol. Metab. 88 (5): 2100–5. doi:10.1210/jc.2002-021799. PMID 12727961.
- ↑ Engkakul P, Mahachoklertwattana P, Poomthavorn P (2011). "Eponym : de Quervain thyroiditis". Eur. J. Pediatr. 170 (4): 427–31. doi:10.1007/s00431-010-1306-4. PMID 20886353.
- ↑ Leibovitch G, Maaravi Y, Shalev O (1989). "Severe facial oedema and glossitis associated with mianserin". Lancet. 2 (8667): 871–2. PMID 2571803.