Breast cancer: Difference between revisions

	Breast Cancer Microchapters
Home
Patient Information
Overview
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating Breast cancer from other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications and Prognosis
Diagnosis
Diagnostic study of choice
History and Symptoms
Physical Examination
Laboratory Findings
Electrocardiogram
X-ray
CT scan
MRI
Echocardiography or Ultrasound
Other Imaging Studies
Other Diagnostic Studies
Treatment
Medical Therapy
Surgery
Primary Prevention
Cost-Effectiveness of Therapy
Future or Investigational Therapies
Case Studies
Case #1
Breast cancer On the Web
Most recent articles
Most cited articles
Review articles
CME Programs
Powerpoint slides
Images
American Roentgen Ray Society Images of Breast cancer All Images X-rays Echo & Ultrasound CT Images MRI
Ongoing Trials at Clinical Trials.gov
US National Guidelines Clearinghouse
NICE Guidance
FDA on Breast cancer
CDC on Breast cancer
Breast cancer in the news
Blogs on Breast cancer
Directions to Hospitals Treating Breast cancer
Risk calculators and risk factors for Breast cancer

VisualWikitext

Latest revision as of 18:34, 4 October 2019

For patient information click here

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Soroush Seifirad, M.D.[2] Mirdula Sharma, MBBS [3] Ammu Susheela, M.D. [4]

Synonyms and keywords: Breast cancers, Breast carcinoma, Breast carcinomas, Breast neoplasm, Breast tumor, Breast tumors, Breast tumour, Breast malignancy

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Breast Cancer from other Diseases

Epidemiology and Demographics

Risk factors

Screening

X Ray Mammography | Breast MRI | Breast Ultrasound | Self Exam | Genetic Testing

Natural History, Complications and Prognosis

Diagnosis

Treatment

Case Studies

Case #1

Related Chapters

External links

General

Clinical

Template:WikiDoc Sources

@@ Line 1: / Line 1: @@
+__NOTOC__
+{{Breast cancer}}
 '''For patient information click [[{{PAGENAME}} (patient information)|here]]'''
-{{Infobox_Disease |
-  Name           = Breast cancer |
+{{CMG}} {{AE}} {{Soroush}} {{MGS}} {{Ammu}}
-  DiseasesDB     = 1598 |
-  ICD10          = {{ICD10|C|50||c|50}} |
+{{SK}} Breast cancers, Breast carcinoma, Breast carcinomas, Breast neoplasm, Breast tumor, Breast tumors, Breast tumour,  Breast malignancy
-  ICD9           = {{ICD9|174}}-{{ICD9|175}} |
-  ICDO           = |
-  OMIM           = 114480 |
-  MedlinePlus    = 000913 |
-  MeshID         = D001943 |
-}}
-{{Breast cancer}}
-{{CMG}}; '''Assistant Editor(s)-In-Chief:''' [[User:Jack Khouri|Jack Khouri]]
 ==[[Breast cancer overview|Overview]]==
@@ Line 18: / Line 12: @@
 ==[[Breast cancer classification|Classification]]==
-[[Breast cancer classification#Major Scheme|Major Scheme]] | [[Breast cancer classification#Staging|Staging]] | [[Breast cancer classification#Pathologic Types|Pathologic Types]] | [[Breast cancer classification#Histologic Types|Histologic Types]]
+==[[Breast cancer pathophysiology|Pathophysiology]]==
+==[[Breast cancer causes|Causes]]==
+==[[Breast cancer differential diagnosis|Differentiating Breast Cancer from other Diseases]]==
 ==[[Breast cancer epidemiology and demographics|Epidemiology and Demographics]]==
-==[[Breast cancer physical examination|Physical Examination]]==
+==[[Breast cancer risk factors|Risk factors]]==
 ==[[Breast cancer screening|Screening]]==
@@ Line 30: / Line 29: @@
 ==Diagnosis==
+[[Breast cancer diagnostic study of choice|Diagnostic Study of Choice]]| [[Breast Biopsy]]|[[Breast cancer history and symptoms| History and Symptoms]] | [[Breast cancer physical examination | Physical Examination]] |[[Breast cancer laboratory tests | Laboratory Findings]] | Electrocardiogram|  [[Breast cancer chest x ray|X Ray]] | [[Breast cancer CT|CT]] scan| [[Breast cancer MRI|MRI]]  | [[Breast cancer echocardiography or ultrasound|Echocardiography or Ultrasound]] | [[Breast cancer other imaging studies|Other Imaging Studies]] | [[Breast cancer other diagnostic studies|Other Diagnostic Studies]]
-==Staging==
-Breast cancer is [[Cancer staging|staged]] according to the TNM system, updated in the American Joint Committee on Cancer (AJCC) Staging Manual, now on its sixth edition.  Prognosis is closely linked to results of staging, and staging is also used to allocate patients to treatments both in clinical trials and clinical practice.
-'''Summary of stages:'''
-* ''Stage 0''  - [[Carcinoma in situ]]
-* ''Stage I''  - Tumor (T) does not involve axillary lymph nodes (N).
-* ''Stage IIA'' – T 2-5 cm, N negative, or T <2 cm and N positive.
-* ''Stage IIB'' – T > 5 cm, N negative, or T 2-5 cm and N positive (< 4 axillary nodes).
-* ''Stage IIIA'' – T > 5 cm, N positive, or  T 2-5 cm with 4 or more axillary nodes
-* ''Stage IIIB'' – T has penetrated chest wall or skin, and may have spread to < 10 axillary N
-* ''Stage IIIC'' – T has > 10 axillary N, 1 or more supraclavicular or infraclavicular N, or internal mammary N.
-* ''Stage IV'' – Distant metastasis (M)
-Breast lesions are examined for certain markers, notably sex steroid hormone receptors.
-About two thirds of postmenopausal breast cancers are [[estrogen receptor]] positive (ER+) and   [[progesterone receptor]] positive (PR+).<ref>Rusiecki JA, Holford TR, Zahm SH, Zheng T. Breast cancer risk factors according to joint estrogen receptor and progesterone receptor status. Cancer Detect Prev 2005;29:419-26</ref> Receptor status modifies the treatment as, for instance, only ER-positive tumors, not ER-negative tumors, are sensitive to hormonal therapy.
-The breast cancer is also usually tested for the presence of human epidermal growth factor receptor 2, a protein also known as HER2, neu or erbB2.  HER2 is a cell-surface protein involved in cell development. In normal cells, HER2 controls aspects of cell growth and division. When activated in cancer cells, HER2 accelerates tumor formation.  About 20-30% of breast cancers overexpress HER2.  Those patients may be candidates for the drug [[trastuzumab]], both in the postsurgical setting (so-called "[[adjuvant]]" therapy), and in the metastatic setting.<ref>[http://www.cancer.gov/cancertopics/factsheet/therapy/herceptin, accessed 1/30/07 cancer.gov]</ref>
 ==[[Breast cancer treatment|Treatment]]==
-[[Breast cancer chemotherapy|Chemotherapy]] | [[Breast cancer bone metastasis|Bone Metastasis]] | [[Metastatic breast cancer treatment |Metastatic Breast Cancer Treatment]]
+[[Breast cancer Medical therapy|Medical Therapy]]| [[Breast cancer Surgery|Surgery]] | [[Breast cancer bone metastasis|Bone Metastasis]]| [[Breast cancer primary prevention|Primary Prevention]] | [[Breast cancer cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Breast cancer future or investigational therapies|Future or Investigational Therapies]]
-==[[Breast cancer primary prevention|Primary Prevention]]==
+==Case Studies==
-[[Breast cancer primary prevention#Phytoestrogens and soy|Phytoestrogens and Soy]] | [[Breast cancer primary prevention#Folic acid (folate)|Folic Acid (Folate)]] | [[Breast cancer primary prevention#Oophorectomy and mastectomy|Oophorectomy and Mastectomy]] | [[Breast cancer primary prevention#Medications|Medications]]
+[[Breast cancer case study one|Case #1]]
-==Metastasis==
-Most people understand breast cancer as something that happens in the breast. However it can [[metastasis]]e (spread) via lymphatics to nearby lymph nodes, usually those under the arm. That is why surgery for breast cancer always involves some type of surgery for the glands under the arm &mdash; either axillary clearance, sampling, or sentinel node biopsy.
-Breast cancer can also spread to other parts of the body via blood vessels. So it can spread to the lungs, pleura (the lining of the lungs), liver, brain, and most commonly to the bones. Seventy percent of the time that breast cancer spreads to other locations, it spreads to bone, especially the vertebrae and the long bones of the arms, legs, and ribs.  Breast cancer cells "set up house" in the bones and form tumors. Usually when breast cancer spreads to bone, it eats away healthy bone, causing weak spots, where the bones can break easily. That is why breast cancer patients are often seen wearing braces or using a wheelchair, and why they complain about aching bones.
-When breast cancer is found in bones, it has usually spread to more than one site. At this stage, it is treatable, often for many years, but it is not curable. Like normal breast cells, these tumors in the bone often thrive on female hormones, especially estrogen. Therefore, the doctor often treats the patient with medicines that lower her estrogen levels.
 ==Related Chapters==
 <div style="-moz-column-count:2; column-count:2;">
 *[[List of breast carcinogenic substances]]
-*[[Mammary tumor]] for breast cancer in other animals
 *[[Breast reconstruction]]
 *[[Alcohol and cancer]]
 *[[Mammography Quality Standards Act]]
-*National Breast Cancer Coalition
 *[[National Comprehensive Cancer Network]]
 *[[Breast Cancer Action]]
@@ Line 79: / Line 54: @@
 *[[Susan G. Komen for the Cure]]
 </div>
-==References==
-<!-- ---------------------------------------------------------------
-See http://en.wikipedia.org/wiki/Wikipedia:Footnotes for a
-discussion of different citation methods and how to generate
-footnotes using the <ref> & </ref> tags and the {{Reflist}} template
--------------------------------------------------------------------- -->
-{{Reflist|2}}
 ==External links== <!-- Before adding links, make sure they meet the requirements as noted in [[WP:EL]] or they may be removed. -->
@@ Line 106: / Line 72: @@
 * [http://www.cancer.org/docroot/LRN/LRN_0.asp?dt=5 American Cancer Society - Learn About Breast Cancer Page]
 * [http://www.cancer.gov/cancertopics/types/breast National Cancer Institute: Breast Cancer]
-* [http://www.imaginis.com Imaginis -Award winning Breast Cancer site]
-===Research and statistics===
-* [http://www.emaxhealth.com/98/ eMaxHealth Breast Cancer] Publishes Research News on Breast Cancer from Research Institutions and Universities
 ===Clinical===
-* [http://www.radiologyinfo.org/en/info.cfm?pg=breastcancer RadiologyInfo] - The radiology information resource for patients: Breast Cancer
 * [http://www.center4research.org/pdf/booklet04bc.pdf Surgery Choices for Women with Early-Stage Breast Cancer, National Cancer Institute]
 * [http://www.center4research.org/bc071502.html Mastectomy vs.n Lumpectomy: Who Decides?, National Research Center for Women & Families]
-* Australia: ''Cancer Control Bulletin'' [http://www.sesiahs.health.nsw.gov.au/publications/cancerControl/26%20Alcohol.PDF Alcohol and cancer risk]
-===Videos===
-*[http://www.healthination.com/breast_cancer.php Health Video: Breast Cancer - Overview, Prevention and Treatment]
-[[es:Cáncer de mama]]
-[[fr:Cancer du sein]]
-[[ja:乳癌]]
-[[pl:Rak sutka]]
-[[pt:Câncer de mama]]
-[[ro:Cancer mamar]]
-[[ru:Злокачественные новообразования молочной железы]]
-[[vi:Ung thư vú]]
-[[tr:Meme kanseri]]
-[[zh:乳癌]]
 {{WikiDoc Help Menu}}
@@ Line 139: / Line 86: @@
 [[Category:Oncology]]
 [[Category:Mature chapter]]
+ [[Category:Up-To-Date]]
+[[Category:Oncology]]
+[[Category:Medicine]]
+[[Category:Gynecology]]
+[[Category:Surgery]]

Breast cancer: Difference between revisions

Latest revision as of 18:34, 4 October 2019

Diagnosis

Case Studies

Related Chapters

External links

General

Clinical

Navigation menu