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==Overview==
==Overview==
The symptoms of acute aortic regurgitation (AR) include [[dyspnea]], [[chest pain]] (when [[aortic dissection]] is the cause of AR), [[weakness]], and symptoms of [[congestive heart failure]]. Chronic AR may be asymptomatic for several years until there is a decrease in the [[stroke volume]] and [[cardiac output]] due to [[heart failure]] progression.  Symptoms of chronic aortic insufficiency include [[exertional dyspnea]], [[orthopnea]], [[paroxysmal nocturnal dyspnea]], and [[palpitations]].
The symptoms of acute aortic regurgitation (AR) include [[dyspnea]], [[chest pain]] (if [[aortic dissection]] is the cause of AR), [[weakness]], and symptoms of [[congestive heart failure]]. Chronic AR may be asymptomatic for several years until there is a decrease in the [[stroke volume]] and [[cardiac output]] due to [[heart failure]] progression.  Symptoms of chronic AR include [[exertional dyspnea]], [[orthopnea]], [[paroxysmal nocturnal dyspnea]], and [[palpitations]].


==History and Symptoms==
==History and Symptoms==
===Acute Aortic Insufficiency===  
===Acute Aortic Regurgitation===  
In acute severe aortic regurgitation (AR), there is a sudden decrease in [[stroke volume]] and increase in left ventricular end diastolic volume and [[left ventricular end diastolic pressure]] which manifests as either sudden and severe [[dyspnea]] and/or [[chest pain]], if there is an [[aortic dissection]].  Based on the history and symptoms, the cause of the acute symptoms can be suspected.
In acute severe AR, there is a sudden decrease in the [[stroke volume]] and increase in left ventricular end diastolic volume and [[left ventricular end diastolic pressure]] which manifests as either sudden and severe [[dyspnea]] and/or [[chest pain]] (if [[aortic dissection]] is the cause of AR).  Based on the history and symptoms, the cause of the acute symptoms can be suspected.


[[Type A aortic dissection]]:
====Type A Aortic Dissection====
* [[Chest pain]] of the following characteristics:
* [[Chest pain]] of the following characteristics:
** Sudden onset
** Sudden onset
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** [[Connective tissue disorder]]
** [[Connective tissue disorder]]


[[Infective endocarditis]]:
====Infective Endocarditis====
* Persistent [[fever]]
* Persistent [[fever]]
* New valvular regurgitation murmur
* New valvular regurgitation murmur
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* History of previous endocarditis
* History of previous endocarditis


Symptomatic severe chronic AR:
====Symptomatic Severe Chronic AR====
* Previous history of aortic valve disease
* Previous history of aortic valve disease



Revision as of 23:02, 6 January 2015

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Cafer Zorkun, M.D., Ph.D. [2]; Varun Kumar, M.B.B.S.; Lakshmi Gopalakrishnan, M.B.B.S.

Overview

The symptoms of acute aortic regurgitation (AR) include dyspnea, chest pain (if aortic dissection is the cause of AR), weakness, and symptoms of congestive heart failure. Chronic AR may be asymptomatic for several years until there is a decrease in the stroke volume and cardiac output due to heart failure progression. Symptoms of chronic AR include exertional dyspnea, orthopnea, paroxysmal nocturnal dyspnea, and palpitations.

History and Symptoms

Acute Aortic Regurgitation

In acute severe AR, there is a sudden decrease in the stroke volume and increase in left ventricular end diastolic volume and left ventricular end diastolic pressure which manifests as either sudden and severe dyspnea and/or chest pain (if aortic dissection is the cause of AR). Based on the history and symptoms, the cause of the acute symptoms can be suspected.

Type A Aortic Dissection

Infective Endocarditis

  • Persistent fever
  • New valvular regurgitation murmur
  • Positive previous blood culture
  • High risk factors:
    • Pre-existing cardiac abnormality
    • Prosthetic valve
    • Recent surgical or medical procedures
    • Intravenous drug use
    • Recent bacterial infection
  • History of previous endocarditis

Symptomatic Severe Chronic AR

  • Previous history of aortic valve disease

Chronic Aortic Insufficiency

In chronic aortic regurgitation (AR), patients are usually asymptomatic for many years as the stroke volume is maintained by increased force of left ventricular contraction secondary to increased left ventricular preload as explained by Frank-Starling mechanism.

With progression of AR, the compensatory mechanisms begin to fail causing gradual enlargement of the left ventricle, thereby progressively increasing left ventricular end diastolic pressure, decreasing stroke volume and cardiac output leading to left ventricular failure manifesting as:

Once symptoms arise, cardiac function usually worsens more rapidly and mortality may exceed 10% per year.

Pertinent Elements in the Past Medical History

References

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