Congestive heart failure treatment of underlying causes
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Treatment of the underlying cause of heart failure including ischemic heart disease, hypertension, renovascular disease, or valvular heart disease is critical in the management of the patient with congestive heart failure.
Ischemic Heart Disease
Underlying ischemic heart disease is the most common cause of chronic congestive heart failure and is the underlying cause of heart failure in 50% to 75% of patients. Ischemic heart disease results in systolic dysfunction of the heart due to irreversible damage of the left ventricle if there has been a prior MI. There can also be viable tissue that is stunned or hibernating as a cause of heart failure. The management of these patients consists of risk factor modification (for example with the use of statins or beta blockers ) as well as the relief of angina (for example with the use of nitrates ). Revascularization (percuataneous coronary intervention or coronary artery bypass grafting) is indicated in the following scenarios:
- To improve symptoms.
- To improve prognosis. If there is a perfusion defect, revascularization may improve prognosis.
- To prevent recurrent heart failure decompensation. If the patient has repeated episodes of congestive heart failure decompensation, revascularization may be indicated.
Hypertension
Hypertension is a common underlying cause of congestive heart failure. There are 2 goals in the treatment of the congestive heart failure patient with hypertension:
1. Reduce the preload and
2. Reduce the afterload
The following agents improve survival in the heart failure patient and are the preferred antihypertensive agents:
- Beta blockers
- Angiotensin-converting enzyme inhibitors
- Angiotensin receptor blockers in patients who cannot tolerate a angiotensin converting enzyme inhibitor
- Aldosterone antagonists
Patients with bilateral renal artery stenosis tend to have a greater risk of flash pulmonary edema than those patients with unilateral renal artery stenosis. This combination of flash pulmonary edema and bilateral renal artery stenosis is known as Pickering syndrome[1].
References
- ↑ Messerli FH, Bangalore S, Makani H, Rimoldi SF, Allemann Y, White CJ, Textor S, Sleight P (2011). "Flash pulmonary oedema and bilateral renal artery stenosis: the Pickering syndrome". European Heart Journal. 32 (18): 2231–5. doi:10.1093/eurheartj/ehr056. PMID 21406441. Retrieved 2013-04-25. Unknown parameter
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