Stomatitis differential diagnosis: Difference between revisions
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|[[Coxsackie virus]] | |[[Coxsackie virus]] | ||
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*[[Fever]] | |||
*Sores in the mouth | |||
*Rash with blisters | |||
*Aches | |||
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*[[Pregnancy]] | |||
*[[immunodeficiency]] | |||
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*History and Physical exam | |||
*Throat swabs | |||
*Swabs from the lesion | |||
*Tzanck test | |||
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*Oral cavity | |||
*Skin | |||
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*Symptomatic treatment | |||
|[[File:Hand foot mouth disease 07.jpeg|Hand-foot-and-mouth disease|50px]] | |[[File:Hand foot mouth disease 07.jpeg|Hand-foot-and-mouth disease|50px]] | ||
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|[[Chickenpox|Chicken pox]] | |[[Chickenpox|Chicken pox]] | ||
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*Conjunctival symptoms | |||
*Catarrhal symptoms | |||
*Characteristic spots on the trunk appearing in two or three waves | |||
*Itching | |||
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*Pregnancy | |||
*Premature infants born to susceptible mothers | |||
*All infants born at less than 28 weeks gestation or who weigh ≤1000 grams | |||
*Immunocompromised | |||
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*History and physical exam | |||
*PCR to detect VZV in skin lesions (vesicles, scabs, maculopapular lesions) | |||
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*Sodium bicarbonate in baths or antihistamines for itching | |||
*Paracetamol (acetaminophen) for fever | |||
*[[Prednisolone]] is contraindicated | |||
|[[File:Chickenpox18.jpeg|Chickenpox|50px]] | |[[File:Chickenpox18.jpeg|Chickenpox|50px]] | ||
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|[[Measles]] | |[[Measles]] | ||
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*[[Fever]] | |||
*[[Rash]] | |||
*[[Cough]] | |||
*[[Coryza]] (runny nose) | |||
*[[Conjunctivitis]] (pink eye) | |||
*[[Malaise]] | |||
*Koplick spots in mouth | |||
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*Unvaccinated individuals<ref name="pmid11135778">{{cite journal| author=Feikin DR, Lezotte DC, Hamman RF, Salmon DA, Chen RT, Hoffman RE| title=Individual and community risks of measles and pertussis associated with personal exemptions to immunization. | journal=JAMA | year= 2000 | volume= 284 | issue= 24 | pages= 3145-50 | pmid=11135778 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11135778 }} </ref> | |||
*Limited vaccination<ref name="pmid9009400">{{cite journal| author=Ratnam S, West R, Gadag V, Williams B, Oates E| title=Immunity against measles in school-aged children: implications for measles revaccination strategies. | journal=Can J Public Health | year= 1996 | volume= 87 | issue= 6 | pages= 407-10 | pmid=9009400 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9009400 }} </ref> | |||
*Crowded and/or unsanitary conditions such as prisons and college dorm rooms | |||
*Traveling to less developed and developing countries where measles is common | |||
* Weakened immune system even if vaccinated | |||
* Winter and spring seasons | |||
* Born after 1956 and never fully vaccinated since. | |||
* Health care workers | |||
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*History and examination | |||
*PCR for Measles-specific IgM antibody | |||
*PCR for Measles RNA | |||
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*Oral cavity | |||
*Skin | |||
*Respiratory tract | |||
*Eyes | |||
*Throat | |||
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*Caused by Morbillivirus | |||
*Primary site of infection is the respiratory epithelium of the nasopharynx | |||
*Transmitted in respiratory secretions, via aerosol droplets containing virus particles | |||
|[[File:Koplikspot1.jpg|Koplick spots (Measles)|50px]] | |[[File:Koplikspot1.jpg|Koplick spots (Measles)|50px]] | ||
|} | |} |
Revision as of 21:13, 15 March 2017
Stomatitis Microchapters |
Diagnosis |
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Treatment |
Case Studies |
Stomatitis differential diagnosis On the Web |
American Roentgen Ray Society Images of Stomatitis differential diagnosis |
Risk calculators and risk factors for Stomatitis differential diagnosis |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sara Mehrsefat, M.D. [2]
Overview
Stomatitis should be differentiated from various subtypes of stomatitis and from many other disease that can involve the oral cavity such as agranulocystosis, Behcet's disease, immunodeficiency and tutors of the oral cavity like leukoplakia etc.[1][2]
Differential diagnosis
Stomatitis must be differentiated from its different kinds and from various other disease that can mimic stomatitis or have accompanying features involving other organs.
Disease | Presentation | Risk Factors | Diagnosis | Systemic Involvement | Important features | Picture |
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Diseases predominantly affecting the oral cavity | ||||||
Squamous cell carcinoma |
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Leukoplakia |
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Melanoma |
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Fordyce spots |
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Torus palatinus |
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Diseases involving oral cavity and other organ systems | ||||||
Behcet's disease |
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Crohn's disease |
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Agranulocytosis |
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Burning mouth syndrome |
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Syphilis[4] |
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Coxsackie virus |
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Chicken pox |
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Measles |
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Stomatitis should be differentiated from other disease as well as from possible underlying conditions causing stomatitis including:[1][2]
- Tumors of the tongue
- Squamous cell carcinoma
- It can prevent as a non healing ulcer or as a mass and is mostly caused by smoking or alcohol utilization.[7]
- Leukoplakia
- Melanoma
- It has the typical abcde characteristics including asymmetry, irregular borders, color change, increase in diameter and evolution and is usually diagnosed in its later stages.[10]
- Fordyce spots
- These are benign neoplasms with sebaceous features
- Torrus Palatinus
- It is a nodular mass on the hard palate, covered with normal mucosa[11]
- Squamous cell carcinoma
- Autoimmune diseases[12]
- Behcet's syndrome[13]
- Crohn's disease
- Agranulocytosis
- Nicorandil induced ulcers
- It is a drug use in angina pectoris
- Burning mouth syndrome
- It is characterized by constant sensation of burning in the mouth in post menopausal women.
- There is no particular cause for it and no specific treatment is done.
- Syphilis
- Coxsackie virus accompanies involvement of the hands and the mouth
- HIV
- VZV or Chicken pox
References
- ↑ 1.0 1.1 Mandell; Gouglas, Gordon; Bennett, John. Principles and Practice of Infectious Diseases. Harvard Medical School: WILEY MEDICAL. p. 383. ISBN 0-471-87643-7. Unknown parameter
|firs1t=
ignored (help) - ↑ 2.0 2.1 Scully C (1999). "A review of common mucocutaneous disorders affecting the mouth and lips". Ann Acad Med Singapore. 28 (5): 704–7. PMID 10597357.
- ↑ Andrès E, Zimmer J, Affenberger S, Federici L, Alt M, Maloisel F. (2006). "Idiosyncratic drug-induced agranulocytosis: Update of an old disorder". Eur J Intern Med. 17 (8): 529–35. Text "pmid 17142169" ignored (help)
- ↑ title="By Internet Archive Book Images [No restrictions], via Wikimedia Commons" href="https://commons.wikimedia.org/wiki/File%3AA_manual_of_syphilis_and_the_venereal_diseases%2C_(1900)_(14595882378).jpg"
- ↑ Feikin DR, Lezotte DC, Hamman RF, Salmon DA, Chen RT, Hoffman RE (2000). "Individual and community risks of measles and pertussis associated with personal exemptions to immunization". JAMA. 284 (24): 3145–50. PMID 11135778.
- ↑ Ratnam S, West R, Gadag V, Williams B, Oates E (1996). "Immunity against measles in school-aged children: implications for measles revaccination strategies". Can J Public Health. 87 (6): 407–10. PMID 9009400.
- ↑ R. Morgan, J. Tsang, N. Harrington & L. Fook (2001). "Survey of hospital doctors' attitudes and knowledge of oral conditions in older patients". Postgraduate medical journal. 77 (908): 392–394. PMID 11375454. Unknown parameter
|month=
ignored (help) - ↑ D. Grady, J. Greene, T. E. Daniels, V. L. Ernster, P. B. Robertson, W. Hauck, D. Greenspan, J. Greenspan & S. Jr Silverman (1990). "Oral mucosal lesions found in smokeless tobacco users". Journal of the American Dental Association (1939). 121 (1): 117–123. PMID 2370378. Unknown parameter
|month=
ignored (help) - ↑ Ann M. Gillenwater, Nadarajah Vigneswaran, Hanadi Fatani, Pierre Saintigny & Adel K. El-Naggar (2013). "Proliferative verrucous leukoplakia (PVL): a review of an elusive pathologic entity!". Advances in anatomic pathology. 20 (6): 416–423. doi:10.1097/PAP.0b013e3182a92df1. PMID 24113312. Unknown parameter
|month=
ignored (help) - ↑ P. DeMatos, D. S. Tyler & H. F. Seigler (1998). "Malignant melanoma of the mucous membranes: a review of 119 cases". Annals of surgical oncology. 5 (8): 733–742. PMID 9869521. Unknown parameter
|month=
ignored (help) - ↑ Barry Ladizinski & Kachiu C. Lee (2014). "A nodular protuberance on the hard palate". JAMA. 311 (15): 1558–1559. doi:10.1001/jama.2014.271. PMID 24737369. Unknown parameter
|month=
ignored (help) - ↑ Magliocca KR, Fitzpatrick SG (2017) Autoimmune Disease Manifestations in the Oral Cavity. Surg Pathol Clin 10 (1):57-88. DOI:10.1016/j.path.2016.11.001 PMID: 28153136
- ↑ Dalghous AM, Freysdottir J, Fortune F (2006). "Expression of cytokines, chemokines, and chemokine receptors in oral ulcers of patients with Behcet's disease (BD) and recurrent aphthous stomatitis is Th1-associated, although Th2-association is also observed in patients with BD". Scand J Rheumatol. 35 (6): 472–5. PMID 17343257.