Cystitis pathophysiology: Difference between revisions
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==Pathophysiology== | ==Pathophysiology== | ||
Cystitis occurs when the normally sterile [[lower urinary tract]] ([[urethra]] and [[bladder]]) | In women, vaginal colonization of the uropathogens leads to the development of a urinary tract infection.<ref name="pmid10969044">{{cite journal| author=Hooton TM| title=Pathogenesis of urinary tract infections: an update. | journal=J Antimicrob Chemother | year= 2000 | volume= 46 Suppl A | issue= | pages= 1-7 | pmid=10969044 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10969044 }} </ref> Cystitis occurs when the normally sterile [[lower urinary tract]] ([[urethra]] and [[bladder]]) are infected by bacteria and become irritated and inflamed. Once [[bacteria]] enter the bladder, they are normally removed through urination. When bacteria multiply faster than they are removed by urination, [[infection]] results. | ||
Once [[bacteria]] enter the bladder, they are normally removed through urination. When bacteria multiply faster than they are removed by urination, [[infection]] results. | |||
Cystitis is rare in males. Females are more prone to the development of cystitis because of their relatively shorter [[urethra]]. Bacteria does not have to travel as far to enter the [[bladder]], which is in part due to the relatively short distance between the opening of the [[urethra]] and the [[anus]]. | Cystitis is rare in males. Females are more prone to the development of cystitis because of their relatively shorter [[urethra]]. Bacteria does not have to travel as far to enter the [[bladder]], which is in part due to the relatively short distance between the opening of the [[urethra]] and the [[anus]]. | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Steven C. Campbell, M.D., Ph.D. Associate Editor(s)-in-Chief: Maliha Shakil, M.D. [2]
Overview
Cystitis occurs when the normally sterile lower urinary tract (urethra and bladder) is infected by bacteria, which leads to irritation and inflammation.
Pathophysiology
In women, vaginal colonization of the uropathogens leads to the development of a urinary tract infection.[1] Cystitis occurs when the normally sterile lower urinary tract (urethra and bladder) are infected by bacteria and become irritated and inflamed. Once bacteria enter the bladder, they are normally removed through urination. When bacteria multiply faster than they are removed by urination, infection results. Cystitis is rare in males. Females are more prone to the development of cystitis because of their relatively shorter urethra. Bacteria does not have to travel as far to enter the bladder, which is in part due to the relatively short distance between the opening of the urethra and the anus.
References
- ↑ Hooton TM (2000). "Pathogenesis of urinary tract infections: an update". J Antimicrob Chemother. 46 Suppl A: 1–7. PMID 10969044.