Cystitis future or investigational therapies

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Usama Talib, BSc, MD [2]

Overview

Cystitis can be hard to treat and recurrence can be an important concern. The complications of cystitis and some carcinomas associated with it sometimes require an aggressive approach. new modalities help improve the existing treatment options and limit further complications. Pulsed radiofrequency treatment is one such advancement.[1]

Future Therapies

  • Pulsed radiofrequency (PRF) treatment of the superior hypogastric plexus may replace conventional treatment invasive and on invasive modalities. It is responsible for providing superior hypogastric plexus with nondestructive modulation, so that majority of the pain signals are transferred from the pelvic viscera.[1]
  • Various approaches are being tried to prevent the developing resistance to certain medications. These include:[2]
    • Avoid prolonged use of broad spectrum antibiotics
    • Optimal dosing
    • Preventing infection
    • Developing new agents

References

  1. 1.0 1.1 Kim JH, Kim E, Kim BI (2016). "Pulsed radiofrequency treatment of the superior hypogastric plexus in an interstitial cystitis patient with chronic pain and symptoms refractory to oral and intravesical medications and bladder hydrodistension: A case report". Medicine (Baltimore). 95 (49): e5549. doi:10.1097/MD.0000000000005549. PMID 27930554.
  2. Wagenlehner FM, Naber KG (2006). "Treatment of bacterial urinary tract infections: presence and future". Eur Urol. 49 (2): 235–44. doi:10.1016/j.eururo.2005.12.017. PMID 16413668.


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