Wilson's disease history and symptoms
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Wilson's disease history and symptoms On the Web
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Patients with Wilson's disease may remain asymptomatic until the copper deposits in the liver and brain mainly. Common hepatic symptoms include abdominal distension, abdominal pain, fatigue, bleeding tendency, and esophageal varices. Common neuropsychiatric symptoms include tremors, ataxia, dysarthria, and impulsiveness. Less common symptoms of wilson's disease include urolithiasis and hematuria.
- Family history of Wilson's disease in any other family member is important in the diagnosis as Wilson's disease is usually inhereted.
- Patients with Wilson's disease may remain asymptomatic until the copper deposits in the liver and brain mainly. 
- Advanced cases of Wilson's disease can be presented as hepatic failure or chronic liver disease which may be associated with cirrhosis. Neurological and psychiatric manifestations are also present in most cases.
- Common symptoms of Wilson's disease include the following: 
Less common symptoms
- Less common symptoms of Wilson's disease include the following:
- Ala A, Walker AP, Ashkan K, Dooley JS, Schilsky ML (2007). "Wilson's disease". Lancet. 369 (9559): 397–408. doi:10.1016/S0140-6736(07)60196-2. PMID 17276780.
- Merle U, Schaefer M, Ferenci P, Stremmel W (2007). "Clinical presentation, diagnosis and long-term outcome of Wilson's disease: a cohort study". Gut. 56 (1): 115–20. doi:10.1136/gut.2005.087262. PMID 16709660.
- European Association for Study of Liver (2012). "EASL Clinical Practice Guidelines: Wilson's disease". J Hepatol. 56 (3): 671–85. doi:10.1016/j.jhep.2011.11.007. PMID 22340672.