Wilson's disease natural history, complications and prognosis

Jump to navigation Jump to search

Wilson's disease Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Wilson's disease from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X-ray

CT

MRI

Echocardiography or Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Wilson's disease natural history, complications and prognosis On the Web

Most recent articles

cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Wilson's disease natural history, complications and prognosis

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Wilson's disease natural history, complications and prognosis

CDC on Wilson's disease natural history, complications and prognosis

Wilson's disease natural history, complications and prognosis in the news

Blogs on Wilson's disease natural history, complications and prognosis

Directions to Hospitals Treating Wilson's disease

Risk calculators and risk factors for Wilson's disease natural history, complications and prognosis

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [2]

Overview

If left untreated, Wilson's disease will lead to death as the copper accumulation in the liver and brain will lead to cirrhosis and severe dystonia respectively. Common complications of Wilson's disease include hepatocellular carcinoma, renal failure, and persistent neurological manifestations. Prognosis of Wilson's disease is usually good in case of early detection and proper treatment.

Natural History, Complications, and Prognosis

Natural history

  • The symptoms of Wilson's disease usually develop between age of 5 and 35 years. However, the symptoms can be presented at any age onset.
  • If left untreated, Wilson's disease will lead to death. The copper accumulation in the liver and the brain will end up with cirrhosis and severe dystonia respectively. [1]

Complications

Prognosis

  • Prognosis of Wilson's disease is usually good with early detection and proper treatment except in the severely advanced patients.

References

  1. European Association for Study of Liver (2012). "EASL Clinical Practice Guidelines: Wilson's disease". J Hepatol. 56 (3): 671–85. doi:10.1016/j.jhep.2011.11.007. PMID 22340672.