Sheehan's syndrome risk factors

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Iqra Qamar M.D.[2]

Overview

Common risk factors in the development of Sheehan's syndrome include pregnancy, severe/massive postpartum hemorrhage (PPH), pituitary mass, pre-existing vascular diseases, autoimmunity, DIC, smaller and rigid sella, and traumatic delivery.

Risk Factors

Common Risk Factors

Less Common Risk Factors

References

  1. Matsuzaki S, Endo M, Ueda Y, Mimura K, Kakigano A, Egawa-Takata T, Kumasawa K, Yoshino K, Kimura T (2017). "A case of acute Sheehan's syndrome and literature review: a rare but life-threatening complication of postpartum hemorrhage". BMC Pregnancy Childbirth. 17 (1): 188. doi:10.1186/s12884-017-1380-y. PMC 5471854. PMID 28615049.
  2. Sheiner E, Sarid L, Levy A, Seidman DS, Hallak M (2005). "Obstetric risk factors and outcome of pregnancies complicated with early postpartum hemorrhage: a population-based study". J. Matern. Fetal. Neonatal. Med. 18 (3): 149–54. doi:10.1080/14767050500170088. PMID 16272036.
  3. Bateman BT, Berman MF, Riley LE, Leffert LR (2010). "The epidemiology of postpartum hemorrhage in a large, nationwide sample of deliveries". Anesth. Analg. 110 (5): 1368–73. doi:10.1213/ANE.0b013e3181d74898. PMID 20237047.
  4. Rouse DJ, Leindecker S, Landon M, Bloom SL, Varner MW, Moawad AH, Spong CY, Caritis SN, Harper M, Wapner RJ, Sorokin Y, Miodovnik M, O'Sullivan MJ, Sibai BM, Langer O (2005). "The MFMU Cesarean Registry: uterine atony after primary cesarean delivery". Am. J. Obstet. Gynecol. 193 (3 Pt 2): 1056–60. doi:10.1016/j.ajog.2005.07.077. PMID 16157111.
  5. Cheng YW, Delaney SS, Hopkins LM, Caughey AB (2009). "The association between the length of first stage of labor, mode of delivery, and perinatal outcomes in women undergoing induction of labor". Am. J. Obstet. Gynecol. 201 (5): 477.e1–7. doi:10.1016/j.ajog.2009.05.024. PMID 19608153.
  6. Blomberg M (2011). "Maternal obesity and risk of postpartum hemorrhage". Obstet Gynecol. 118 (3): 561–8. doi:10.1097/AOG.0b013e31822a6c59. PMID 21860284.
  7. Wetta LA, Szychowski JM, Seals S, Mancuso MS, Biggio JR, Tita AT (2013). "Risk factors for uterine atony/postpartum hemorrhage requiring treatment after vaginal delivery". Am. J. Obstet. Gynecol. 209 (1): 51.e1–6. doi:10.1016/j.ajog.2013.03.011. PMC 3788839. PMID 23507549.
  8. Kramer MS, Berg C, Abenhaim H, Dahhou M, Rouleau J, Mehrabadi A, Joseph KS (2013). "Incidence, risk factors, and temporal trends in severe postpartum hemorrhage". Am. J. Obstet. Gynecol. 209 (5): 449.e1–7. doi:10.1016/j.ajog.2013.07.007. PMID 23871950.
  9. Sharp GC, Saunders PT, Greene SA, Morris AD, Norman JE (2014). "Intergenerational transmission of postpartum hemorrhage risk: analysis of 2 Scottish birth cohorts". Am. J. Obstet. Gynecol. 211 (1): 51.e1–7. doi:10.1016/j.ajog.2014.01.012. PMID 24412115.
  10. Bruning AH, Heller HM, Kieviet N, Bakker PC, de Groot CJ, Dolman KM, Honig A (2015). "Antidepressants during pregnancy and postpartum hemorrhage: a systematic review". Eur. J. Obstet. Gynecol. Reprod. Biol. 189: 38–47. doi:10.1016/j.ejogrb.2015.03.022. PMID 25845914.
  11. Oberg AS, Hernandéz-Diaź S, Frisell T, Greene MF, Almqvist C, Bateman BT (2014). "Genetic contribution to postpartum haemorrhage in Swedish population: cohort study of 466,686 births". BMJ. 349: g4984. PMC 4131501. PMID 25121825.
  12. Barkan AL (1989). "Pituitary atrophy in patients with Sheehan's syndrome". Am. J. Med. Sci. 298 (1): 38–40. PMID 2750772.
  13. Keleştimur F (2003). "Sheehan's syndrome". Pituitary. 6 (4): 181–8. PMID 15237929.
  14. "AUTOANTIBODIES IN SHEEHAN'S SYNDROME - ScienceDirect".
  15. Falorni A, Minarelli V, Bartoloni E, Alunno A, Gerli R (2014). "Diagnosis and classification of autoimmune hypophysitis". Autoimmun Rev. 13 (4–5): 412–6. doi:10.1016/j.autrev.2014.01.021. PMID 24434361.

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