Palmar erythema

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Cafer Zorkun, M.D., Ph.D. [2] Luke Rusowicz-Orazem, B.S.

Overview

Palmar erythema is reddening of the palms at the thenar and hypothenar eminences. It is associated with various physiological as well as pathological changes, the principal one of which is portal hypertension. It is also seen in patients with liver dysfunction.

Causes

Life Threatening Causes

• Chronic liver disease 
• Congenital syphilis
• Hepatic failure
• Hepatopulmonary hypertension
• Poisoning
• Secondary syphilis

Common Causes

• Eczema
• Psoriasis

Causes by Organ System

Cardiovascular	Deep telangiectasias, Hepatopulmonary hypertension, Kawasaki disease, Portal hypertension
Chemical/Poisoning	Poisoning
Dental	No underlying causes
Dermatologic	Eczema , Palmar-plantar erythrodysesthesia, Psoriasis
Drug Side Effect	Axitinib, Cabozantinib, Capecitabine, Cytosine arabinoside, Dabrafenib, Docetaxel, Doxorubicin, Everolimus, Floxuridine, Fluorouracil, Hydroxycarbamide, Idarubicin, Ixabepilone, Lapatinib ditosylate, Lenvatinib, Necitumumab, Pazopanib, Regorafenib, Sorafenib, Tegafur, Trametinib
Ear Nose Throat	No underlying causes
Endocrine	Hyperoestrogenic states, Hyperthyroidism, Thyrotoxicosis
Environmental	No underlying causes
Gastroenterologic	Chronic liver disease , Hepatic failure, Hepatopulmonary hypertension, Wilson disease
Genetic	Wilson disease
Hematologic	Polycythemia
Iatrogenic	No underlying causes
Infectious Disease	Coxsackievirus a infection , Rocky mountain spotted fever, Secondary syphilis
Musculoskeletal/Orthopedic	No underlying causes
Neurologic	Wilson disease
Nutritional/Metabolic	No underlying causes
Obstetric/Gynecologic	Pregnancy
Oncologic	Palmar-plantar erythrodysesthesia
Ophthalmologic	No underlying causes
Overdose/Toxicity	No underlying causes
Psychiatric	No underlying causes
Pulmonary	No underlying causes
Renal/Electrolyte	No underlying causes
Rheumatology/Immunology/Allergy	Kawasaki disease, Psoriasis, Rheumatoid arthritis , Rheumatoid disease
Sexual	Congenital syphilis, Secondary syphilis
Trauma	No underlying causes
Urologic	No underlying causes
Miscellaneous	No underlying causes

Causes in Alphabetical Order

• Axitinib
• Cabozantinib
• Capecitabine
• Chronic liver disease 
• Congenital syphilis
• Coxsackievirus a infection
• Cytosine arabinoside
• Dabrafenib
• Deep telangiectasias
• Docetaxel
• Doxorubicin
• Eczema 
• Everolimus
• Floxuridine
• Fluorouracil
• Hepatic failure
• Hepatopulmonary hypertension
• Hydroxycarbamide
• Hyperoestrogenic states
• Hyperthyroidism
• Idarubicin
• Ixabepilone
• Kawasaki disease
• Lapatinib ditosylate
• Lenvatinib
• Necitumumab
• Palmar-plantar erythrodysesthesia
• Pazopanib
• Poisoning
• Polycythemia
• Portal hypertension
• Pregnancy
• Psoriasis
• Regorafenib
• Rheumatoid arthritis 
• Rheumatoid disease
• Rocky mountain spotted fever
• Secondary syphilis
• Sorafenib
• Tegafur
• Thyrotoxicosis
• Trametinib
• Wilson disease

External links

• Template:GPnotebook
• Template:DiseasesDB

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