Edoxudine

Edoxudine

Gene therapy
Clinical data
ATC code	D06BB09 (WHO)
Physiological data
Legal status
Pharmacokinetic data
Identifiers
IUPAC name 5-ethyl-1-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
CAS Number	15176-29-1 Y
PubChem Template:Abbreviation	66377
ChemSpider	59752 N
UNII	15ZQM81Y3R
ChEMBL	ChEMBL318153 N
Chemical and physical data
Formula	C11H16N2O5
Molar mass	256.25514
3D model (JSmol)	Interactive image
SMILES O=C/1NC(=O)N(\C=C\1CC)[C@@H]2O[C@@H]([C@@H](O)C2)CO
InChI InChI=1S/C11H16N2O5/c1-2-6-4-13(11(17)12-10(6)16)9-3-7(15)8(5-14)18-9/h4,7-9,14-15H,2-3,5H2,1H3,(H,12,16,17)/t7-,8+,9+/m0/s1 N Key:XACKNLSZYYIACO-DJLDLDEBSA-N N
Template:XmarkY (what is this?)  (verify)

Edoxudine (or edoxudin) is an Antiviral drug. It is an analog of thymidine, a nucleoside.

It has shown effectiveness against herpes simplex virus.

Synthesis

Bergstrom, Donald E.; Ruth, Jerry L. (1976). "Synthesis of C-5 substituted pyrimidine nucleosides via organopalladium intermediates". Journal of the American Chemical Society. 98 (6): 1587–9. doi:10.1021/ja00422a056. PMID 1249369.

References

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