Cholestasis causes
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Causes
There are many causes of cholestasis.
- Extrahepatic cholestasis occurs outside the liver. It can be caused by:
- Bile duct tumors
- Cysts
- Narrowing of the bile duct (strictures)
- Stones in the common bile duct
- Pancreatitis
- Pancreatic tumor or pseudocyst
- Pressure on an organ due to a nearby mass or tumor
- Primary sclerosing cholangitis
- Intrahepatic cholestasis occurs inside the liver. It can be caused by:
- Alcoholic liver disease
- Amyloidosis
- Bacterial abscess in the liver
- Being fed through a vein (IV)
- Lymphoma
- Intrahepatic cholestasis of pregnancy
- Primary biliary cirrhosis
- Primary sclerosing cholangitis
- Sarcoidosis
- Serious infections that have spread through the bloodstream (sepsis)
- Tuberculosis
- Viral hepatitis
- Sjogren syndrome
- Certain medications can also cause cholestasis.
Common Causes
Causes by Organ System
Causes in Alphabetical Order