Brucellosis epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Raviteja Guddeti, M.B.B.S. [2] Danitza Lukac Vishal Devarkonda, M.B.B.S[3]


The incidence of brucellosis is estimated to vary from 0.01 to 200 per 100,000 individuals in endemic countries. The case fatality rate of brucellosis is less than 2% when untreated. The majority of disease is reported in Mediterranean basin, South and Central America, Eastern Europe, Asia, Africa, the Caribbean and the Middle East. Patients of age group 20 and 45 years are affected. Men are more affected then women.

Epidemiology and Demographics

Epidemiology and Demographics of Brucellosis include:[1][2][3][4][5]


  • The incidence in different endemic countries varies between 0.01 and 200 per 100,000 individuals.
  • The low incidence reported in known Brucellosis-endemic areas may reflect low levels of surveillance and reporting.[3]

Case Fatality Rate

Developed countries

Developed countries like the Unites States (0.02-0.09/100,000), Italy (1.40/100,000), Germany (0.03/100,000) and Greece (4.00/100,00) with strict pasteurization laws, animal control/slaughter regulations and brucellosis surveillance programs have reported low incidence of brucellosis.[6]

Developing countries

Developing countries like Iraq (53.29-268.81/100,000), Iran (0.73-141.60/100,000), Jordon (25.70-130/100,000), Kyrgyzstan (88/100,000) and Mexico (26.60/100,000) due to lack of strict pasteurization laws, animal control/slaughter regulations and brucellosis surveillance programs have reported much higher incidence of brucellosis.[6]






  1. Brucellosis. CDC. Accessed on February 3, 2016
  2. Mailles A, Garin-Bastuji B, Lavigne JP, Jay M, Sotto A, Maurin M; et al. (2016). "Human brucellosis in France in the 21st century: Results from national surveillance 2004-2013". Med Mal Infect. 46 (8): 411–418. doi:10.1016/j.medmal.2016.08.007. PMID 27717526.
  3. 3.0 3.1 Corbel MJ (1997). "Brucellosis: an overview". Emerg Infect Dis. 3 (2): 213–21. doi:10.3201/eid0302.970219. PMC 2627605. PMID 9204307.
  4. 4.0 4.1 Brucelosis. Commonwealth of Massachusetts. Accessed on February 3, 2016
  5. 5.0 5.1 5.2 FAO/WHO/OIE Brucellosis in humans and animals. WHO (2006). Accessed on February 3, 2016
  6. 6.0 6.1 "Global burden of brucellosis".