Anileridine

Anileridine

Clinical data
AHFS/Drugs.com	Monograph
Routes of administration	Tablets, injection
ATC code	N01AH05 (WHO)
Legal status
Legal status	AU: S8 (Controlled) CA: ℞-only US: Schedule II
Pharmacokinetic data
Protein binding	> 95%
Metabolism	Hepatic
Identifiers
IUPAC name Ethyl 1-[2-(4-aminophenyl)ethyl]-4-phenylpiperidine-4-carboxylate
CAS Number	144-14-9 Y
PubChem CID	8944
DrugBank	DB00913 Y
ChemSpider	8600 Y
UNII	71Q1A3O279
KEGG	D02941 Y
ChEBI	CHEBI:61203 Y
ChEMBL	ChEMBL1201347 N
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}
Chemical and physical data
Formula	C22H28N2O2
Molar mass	352.47 g/mol
3D model (JSmol)	Interactive image
Melting point	83 °C (181.4 °F)
SMILES O=C(OCC)C3(c1ccccc1)CCN(CCc2ccc(N)cc2)CC3
InChI InChI=1S/C22H28N2O2/c1-2-26-21(25)22(19-6-4-3-5-7-19)13-16-24(17-14-22)15-12-18-8-10-20(23)11-9-18/h3-11H,2,12-17,23H2,1H3 Y Key:LKYQLAWMNBFNJT-UHFFFAOYSA-N Y
NY (what is this?)  (verify)

WikiDoc Resources for Anileridine
Articles
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Evidence Based Medicine
Cochrane Collaboration on Anileridine Bandolier on Anileridine TRIP on Anileridine
Clinical Trials
Ongoing Trials on Anileridine at Clinical Trials.gov Trial results on Anileridine Clinical Trials on Anileridine at Google
Guidelines / Policies / Govt
US National Guidelines Clearinghouse on Anileridine NICE Guidance on Anileridine NHS PRODIGY Guidance FDA on Anileridine CDC on Anileridine
Books
Books on Anileridine
News
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Commentary
Blogs on Anileridine
Definitions
Definitions of Anileridine
Patient Resources / Community
Patient resources on Anileridine Discussion groups on Anileridine Patient Handouts on Anileridine Directions to Hospitals Treating Anileridine Risk calculators and risk factors for Anileridine
Healthcare Provider Resources
Symptoms of Anileridine Causes & Risk Factors for Anileridine Diagnostic studies for Anileridine Treatment of Anileridine
Continuing Medical Education (CME)
CME Programs on Anileridine
International
Anileridine en Espanol Anileridine en Francais
Business
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Experimental / Informatics
List of terms related to Anileridine

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Anileridine (trade name: Leritine) is a synthetic analgesic drug and is a member of the piperidine class of analgesic agents developed by Merck & Co. in the 1950s. It differs from pethidine (meperidine) in that the N-methyl group of meperidine is replaced by an N-aminophenethyl group, which increases its analgesic activity.

Anileridine is no longer manufactured in the US or Canada.

Administration

As tablets or injection.

Pharmacokinetics

Anileridine usually takes effect within 15 minutes of either oral or intravenous administration, and lasts 2–3 hours. It is mostly metabolized by the liver.