Anaphylaxis physical examination

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1], Associate Editor(s)-in-Chief: Dushka Riaz, MD

Overview

Patients with anaphylaxis usually appear flushed. Physical examination of patients with anaphylaxis is usually remarkable for swollen lips or other areas, wheezing, cyanosis, and low blood pressure. It is vital for the physician to assess cardiac and respiratory symptoms for any compromise as soon as possible. [1]

The diagnosis is likely when any one of the following criteria is met: [2]

Physical Examination

Physical examination of patients with anaphylaxis is usually remarkable for flushing and pruritis. The presentation can vary for patients and it is important not to delay treatment. [3] [4] [5] [6] [7] [8]

Appearance of the Patient

Vital Signs

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Heart

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The health care provider will wait to test for the specific allergen that caused anaphylaxis (if the cause is not obvious) until after treatment.

References

  1. Schmoldt A, Benthe HF, Haberland G (1975). "Digitoxin metabolism by rat liver microsomes". Biochem Pharmacol. 24 (17): 1639–41. PMID https://doi.org/10.1016/S0091-6749(18)30572-4 Check |pmid= value (help).
  2. Bjornsson HM, Graffeo CS (2010). "Improving diagnostic accuracy of anaphylaxis in the acute care setting". West J Emerg Med. 11 (5): 456–61. PMC 3027438. PMID 21293765.
  3. Schmoldt A, Benthe HF, Haberland G (1975). "Digitoxin metabolism by rat liver microsomes". Biochem Pharmacol. 24 (17): 1639–41. PMID 10.1016/S1081-1206(10)61367-1. doi: 10.1016/S1081-1206(10)61367-1. Check |pmid= value (help).
  4. Schmoldt A, Benthe HF, Haberland G (1975). "Digitoxin metabolism by rat liver microsomes". Biochem Pharmacol. 24 (17): 1639–41. PMID https://doi.org/10.1186/s13223-018-0283-4 Check |pmid= value (help).
  5. Waserman S, Chad Z, Francoeur MJ, Small P, Stark D, Vander Leek TK; et al. (2010). "Management of anaphylaxis in primary care: Canadian expert consensus recommendations". Allergy. 65 (9): 1082–92. doi:10.1111/j.1398-9995.2010.02418.x. PMID 20584005.
  6. Simons FE (2010). "Anaphylaxis". J Allergy Clin Immunol. 125 (2 Suppl 2): S161–81. doi:10.1016/j.jaci.2009.12.981. PMID 20176258.
  7. Simons FE, Ardusso LR, Bilò MB, El-Gamal YM, Ledford DK, Ring J; et al. (2011). "World Allergy Organization anaphylaxis guidelines: summary". J Allergy Clin Immunol. 127 (3): 587-93.e1-22. doi:10.1016/j.jaci.2011.01.038. PMID 21377030.
  8. Brown SG, Mullins RJ, Gold MS (2006). "Anaphylaxis: diagnosis and management". Med J Aust. 185 (5): 283–9. doi:10.5694/j.1326-5377.2006.tb00619.x. PMID 16948628.


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