Acinic cell carcinoma surgery

Jump to navigation Jump to search

Acinic cell carcinoma Microchapters


Patient Information


Historical Perspective




Differentiating Acinic cell carcinoma from other Diseases

Epidemiology and Demographics

Risk Factors


Natural History, Complications and Prognosis


Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

X Ray



Echocardiography or Ultrasound

Other Imaging Findings

Other Diagnostic Studies



Medical Therapy

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case studies

Case #1

Acinic cell carcinoma surgery On the Web

Most recent articles

cited articles

Review articles

CME Programs

Powerpoint slides


American Roentgen Ray Society Images of Acinic cell carcinoma surgery

All Images
Echo & Ultrasound
CT Images

Ongoing Trials at Clinical

US National Guidelines Clearinghouse

NICE Guidance

FDA on Acinic cell carcinoma surgery

CDC on Acinic cell carcinoma surgery

Acinic cell carcinoma surgery in the news

Blogs on Acinic cell carcinoma surgery

Directions to Hospitals Treating Acinic cell carcinoma

Risk calculators and risk factors for Acinic cell carcinoma surgery

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ramyar Ghandriz MD[2]


Acinic cell carcinoma is usually anatomically accessible tumor and patient do not show far metastasis at the time of diagnosis, the treatment of choice is surgery with resection of all free margins. Since acinic cell carcinoma could be neglected, a high rate of recurrence after first resection have been reported. low grade acinic cell carcinoma will be cured with surgery alone, but the site of origin indicates extension of resection. Superficial parotidectomy often effects complete removal of acinic cell carcinoma, but conservative parotidectomy is indicated if the deep lobe is involved. Initial approach would be more aggressive if the tumor is locally advanced acinic cell carcinoma, the facial nerve cannot be preserved, it must be resected and reconstructed with an autograft from greater auricular or sural nerve. Elective neck dissection is not recommended in acinic cell carcinoma, because of low risk of regional lymph node metastasis. However, studies have revealed additional neck dissection decrease the rate of recurrence.



  • Elective neck dissection is not recommended in acinic cell carcinoma, because of low risk of regional lymph node metastasis. However studies have revealed additional neck dissection decrease the rate of recurrence.[3]
  • Patients with large volume or high grade tumor would likely benefit from elective neck dissection at level II, III, IV.
  • Positive cervical lymph nodes are adverse prognosticator which indicate a necessary therapeutic neck dissection as a part of surgical approach, and raise suspicions of high grade transformation of acinic cell carcinoma.


  1. Vander Poorten, V.; Triantafyllou, A.; Thompson, L. D. R.; Bishop, J.; Hauben, E.; Hunt, J.; Skalova, A.; Stenman, G.; Takes, R. P.; Gnepp, D. R.; Hellquist, H.; Wenig, B.; Bell, D.; Rinaldo, A.; Ferlito, A. (2015). "Salivary acinic cell carcinoma: reappraisal and update". European Archives of Oto-Rhino-Laryngology. 273 (11): 3511–3531. doi:10.1007/s00405-015-3855-7. ISSN 0937-4477.
  2. Lewis, Jean E.; Olsen, Kerry D.; Weiland, Louis H. (1991). "Acinic cell carcinoma. Clinicopathologic review". Cancer. 67 (1): 172–179. doi:10.1002/1097-0142(19910101)67:1<172::AID-CNCR2820670129>3.0.CO;2-X. ISSN 0008-543X.
  3. Neskey, David M.; Klein, Jonah D.; Hicks, Stephanie; Garden, Adam S.; Bell, Diana M.; El-Naggar, Adel K.; Kies, Merrill S.; Weber, Randal S.; Kupferman, Michael E. (2013). "Prognostic Factors Associated With Decreased Survival in Patients With Acinic Cell Carcinoma". JAMA Otolaryngology–Head & Neck Surgery. 139 (11): 1195. doi:10.1001/jamaoto.2013.4728. ISSN 2168-6181.

Template:WH Template:WS