Acinic cell carcinoma causes

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ramyar Ghandriz MD[2]


There may be a co-incidence with some inherited genetic situations, like Cowden syndrome and acinic cell carcinom. recurrent abnormality of cytogeic t(12;15) ETV6-NRTK3 is also reported in cancerous cells.


Common Causes

Common causes of acinic cell carcinoma may include [1][2][3] :

Genetic Causes

  • acinic cell carcinoma is caused by a mutation in the BRCA-1 gene.[4]
  • T(12;15)(p13;q25)ETV6-NTRK3 is now proven to be the gold standard of acinic cell carcinoma and may be a related case.[5]

Causes by Organ System

Cardiovascular No underlying causes
Chemical/Poisoning No underlying causes
Dental No underlying causes
Dermatologic No underlying causes
Drug Side Effect No underlying causes
Ear Nose Throat No underlying causes
Endocrine No underlying causes
Environmental No underlying causes
Gastroenterologic No underlying causes
Genetic BRCA-1 mutation,T(12;15)(p13;q25)ETV6-NTRK3
Hematologic No underlying causes
Iatrogenic Radiation exposure
Infectious Disease No underlying causes
Musculoskeletal/Orthopedic No underlying causes
Neurologic No underlying causes
Nutritional/Metabolic No underlying causes
Obstetric/Gynecologic No underlying causes
Oncologic No underlying causes
Ophthalmologic No underlying causes
Overdose/Toxicity No underlying causes
Psychiatric No underlying causes
Pulmonary No underlying causes
Renal/Electrolyte No underlying causes
Rheumatology/Immunology/Allergy No underlying causes
Sexual No underlying causes
Trauma No underlying causes
Urologic No underlying causes
Miscellaneous Cowden sybdrome

Causes in Alphabetical Order

List the causes of the disease in alphabetical order:


  1. Saku T, Hayashi Y, Takahara O, Matsuura H, Tokunaga M, Tokunaga M; et al. (1997). "Salivary gland tumors among atomic bomb survivors, 1950-1987". Cancer. 79 (8): 1465–75. PMID 9118025.
  2. Depowski PL, Setzen G, Chui A, Koltai PJ, Dollar J, Ross JS (1999). "Familial occurrence of acinic cell carcinoma of the parotid gland". Arch Pathol Lab Med. 123 (11): 1118–20. doi:10.1043/0003-9985(1999)123<1118:FOOACC>2.0.CO;2. PMID 10539921.
  3. Villeneuve, Hugo; Tremblay, Steve; Galiatsatos, Polymnia; Hamel, Nancy; Guertin, Louis; Morency, Renald; Tischkowitz, Marc (2011). "Acinic cell carcinoma of the retromolar trigone region: expanding the tumor phenotype in Cowden syndrome?". Familial Cancer. 10 (4): 691–694. doi:10.1007/s10689-011-9472-8. ISSN 1389-9600.
  4. Ripamonti, Carla B; Colombo, Mara; Mondini, Patrizia; Siranoush, Manoukian; Peissel, Bernard; Bernard, Loris; Radice, Paolo; Carcangiu, Maria Luisa (2013). "First description of an acinic cell carcinoma of the breast in a BRCA1 mutation carrier: a case report". BMC Cancer. 13 (1). doi:10.1186/1471-2407-13-46. ISSN 1471-2407.
  5. Shah, Akeesha A.; Wenig, Bruce M.; LeGallo, Robin D.; Mills, Stacey E.; Stelow, Edward B. (2014). "Morphology in Conjunction with Immunohistochemistry is Sufficient for the Diagnosis of Mammary Analogue Secretory Carcinoma". Head and Neck Pathology. 9 (1): 85–95. doi:10.1007/s12105-014-0557-1. ISSN 1936-055X.

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