CYP4F22
cytochrome P450, family 4, subfamily F, polypeptide 22 | |
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Identifiers | |
Symbol | CYP4F22 |
Entrez | 126410 |
HUGO | 26820 |
OMIM | 611495 |
RefSeq | NM_173483 |
UniProt | Q6NT55 |
Other data | |
Locus | Chr. 19 p13.12 |
WikiDoc Resources for CYP4F22 |
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Ongoing Trials on CYP4F22 at Clinical Trials.gov Clinical Trials on CYP4F22 at Google
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US National Guidelines Clearinghouse on CYP4F22
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CYP4F22 (cytochrome P450, family 4, subfamily F, polypeptide 22) is a protein which in humans is encoded by the CYP4F22 gene.[1]
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This gene is part of a cluster of cytochrome P450 genes on chromosome 19 and encodes an enzyme thought to play a role in the 12(R)-lipoxygenase pathway. Mutations in this gene are the cause of ichthyosis lamellar type 3.[2]
References
- ↑ Lefèvre C, Bouadjar B, Ferrand V, Tadini G, Mégarbané A, Lathrop M, Prud'homme JF, Fischer J (2006). "Mutations in a new cytochrome P450 gene in lamellar ichthyosis type 3". Hum. Mol. Genet. 15 (5): 767–76. doi:10.1093/hmg/ddi491. PMID 16436457. Unknown parameter
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ignored (help) - ↑ "Entrez Gene: CYP4F22".
This article incorporates text from the United States National Library of Medicine, which is in the public domain.