CNGB1: Difference between revisions

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Identifiers
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External IDs	GeneCards: [1]
Orthologs
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Latest revision as of 23:34, 21 November 2017

Cyclic nucleotide gated channel beta 1, also known as CNGB1, is a human gene encoding an ion channel protein.^[1]

References

↑ "Entrez Gene: CNGB1 cyclic nucleotide gated channel beta 1".

Hofmann F, Biel M, Kaupp UB (2006). "International Union of Pharmacology. LI. Nomenclature and structure-function relationships of cyclic nucleotide-regulated channels". Pharmacol. Rev. 57 (4): 455–62. doi:10.1124/pr.57.4.8. PMID 16382102.
Kondo H, Qin M, Mizota A, et al. (2005). "A homozygosity-based search for mutations in patients with autosomal recessive retinitis pigmentosa, using microsatellite markers". Invest. Ophthalmol. Vis. Sci. 45 (12): 4433–9. doi:10.1167/iovs.04-0544. PMID 15557452.
Trudeau MC, Zagotta WN (2002). "Mechanism of calcium/calmodulin inhibition of rod cyclic nucleotide-gated channels". Proc. Natl. Acad. Sci. U.S.A. 99 (12): 8424–9. doi:10.1073/pnas.122015999. PMC 123083. PMID 12048242.
Poetsch A, Molday LL, Molday RS (2002). "The cGMP-gated channel and related glutamic acid-rich proteins interact with peripherin-2 at the rim region of rod photoreceptor disc membranes". J. Biol. Chem. 276 (51): 48009–16. doi:10.1074/jbc.M108941200. PMID 11641407.
Bareil C, Hamel CP, Delague V, et al. (2001). "Segregation of a mutation in CNGB1 encoding the beta-subunit of the rod cGMP-gated channel in a family with autosomal recessive retinitis pigmentosa". Hum. Genet. 108 (4): 328–34. doi:10.1007/s004390100496. PMID 11379879.
Pogacić V, Dragon F, Filipowicz W (2000). "Human H/ACA small nucleolar RNPs and telomerase share evolutionarily conserved proteins NHP2 and NOP10". Mol. Cell. Biol. 20 (23): 9028–40. doi:10.1128/MCB.20.23.9028-9040.2000. PMC 86556. PMID 11074001.
Körschen HG, Beyermann M, Müller F, et al. (1999). "Interaction of glutamic-acid-rich proteins with the cGMP signalling pathway in rod photoreceptors". Nature. 400 (6746): 761–6. doi:10.1038/23468. PMID 10466724.
Ardell MD, Aragon I, Oliveira L, et al. (1996). "The beta subunit of human rod photoreceptor cGMP-gated cation channel is generated from a complex transcription unit". FEBS Lett. 389 (2): 213–8. doi:10.1016/0014-5793(96)00588-1. PMID 8766832.
Chen TY, Peng YW, Dhallan RS, et al. (1993). "A new subunit of the cyclic nucleotide-gated cation channel in retinal rods". Nature. 362 (6422): 764–7. doi:10.1038/362764a0. PMID 7682292.
Ardell MD, Makhija AK, Oliveira L, et al. (1995). "cDNA, gene structure, and chromosomal localization of human GAR1 (CNCG3L), a homolog of the third subunit of bovine photoreceptor cGMP-gated channel". Genomics. 28 (1): 32–8. doi:10.1006/geno.1995.1102. PMID 7590744.
Chen TY, Illing M, Molday LL, et al. (1994). "Subunit 2 (or beta) of retinal rod cGMP-gated cation channel is a component of the 240-kDa channel-associated protein and mediates Ca(2+)-calmodulin modulation". Proc. Natl. Acad. Sci. U.S.A. 91 (24): 11757–61. doi:10.1073/pnas.91.24.11757. PMC 45311. PMID 7526403.
Fujii Y, Zhao FX, Fu SC, et al. (1992). "Stable preparation of aldose reductase isoenzymes from human placenta". Protein Expr. Purif. 2 (5–6): 420–5. doi:10.1016/1046-5928(91)90103-P. PMID 1821816.

External links

GeneReviews/NCBI/NIH/UW entry on Retinitis Pigmentosa Overview
CNGB1+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)
Human CNGB1 genome location and CNGB1 gene details page in the UCSC Genome Browser.
Human GAR1 genome location and GAR1 gene details page in the UCSC Genome Browser.

Stub icon

This membrane protein–related article is a stub. You can help Wikipedia by expanding it.

[entrez-1] "Entrez Gene: CNGB1 cyclic nucleotide gated channel beta 1".

[1]

@@ Line 1: / Line 1: @@
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+{{Infobox_gene}}
-{{PBB_Controls
+'''Cyclic nucleotide gated channel beta 1''', also known as '''CNGB1''', is a human [[gene]] encoding an [[ion channel]] protein.<ref name="entrez">{{cite web | title = Entrez Gene: CNGB1 cyclic nucleotide gated channel beta 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1258| accessdate = }}</ref>
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-{{GNF_Protein_box
- | image =
- | image_source =
- | PDB =
- | Name = Cyclic nucleotide gated channel beta 1
- | HGNCid = 2151
- | Symbol = CNGB1
- | AltSymbols =; CNCG2; CNCG3L; CNGB1B; GAR1; GARP; RCNC2; RCNCb; RCNCbeta
- | OMIM = 600724
- | ECnumber =
- | Homologene = 993
- | MGIid =
- | GeneAtlas_image1 = PBB_GE_CNGB1_207342_at_tn.png
- | GeneAtlas_image2 = PBB_GE_CNGB1_211099_s_at_tn.png
- | GeneAtlas_image3 = PBB_GE_CNGB1_210769_at_tn.png
- | Function = {{GNF_GO|id=GO:0000166 |text = nucleotide binding}} {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0005216 |text = ion channel activity}} {{GNF_GO|id=GO:0005222 |text = intracellular cAMP activated cation channel activity}} {{GNF_GO|id=GO:0015276 |text = ligand-gated ion channel activity}} {{GNF_GO|id=GO:0030552 |text = cAMP binding}}
- | Component = {{GNF_GO|id=GO:0005624 |text = membrane fraction}} {{GNF_GO|id=GO:0005887 |text = integral to plasma membrane}} {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0017071 |text = intracellular cyclic nucleotide activated cation channel complex}}
- | Process = {{GNF_GO|id=GO:0006811 |text = ion transport}} {{GNF_GO|id=GO:0007601 |text = visual perception}} {{GNF_GO|id=GO:0007602 |text = phototransduction}} {{GNF_GO|id=GO:0045494 |text = photoreceptor cell maintenance}}
- | Orthologs = {{GNF_Ortholog_box
-    | Hs_EntrezGene = 1258
-    | Hs_Ensembl = ENSG00000070729
-    | Hs_RefseqProtein = NP_001288
-    | Hs_RefseqmRNA = NM_001297
-    | Hs_GenLoc_db =
-    | Hs_GenLoc_chr = 16
-    | Hs_GenLoc_start = 56475348
-    | Hs_GenLoc_end = 56562513
-    | Hs_Uniprot = Q14028
-    | Mm_EntrezGene =
-    | Mm_Ensembl =
-    | Mm_RefseqmRNA =
-    | Mm_RefseqProtein =
-    | Mm_GenLoc_db =
-    | Mm_GenLoc_chr =
-    | Mm_GenLoc_start =
-    | Mm_GenLoc_end =
-    | Mm_Uniprot =
-  }}
-}}
-'''Cyclic nucleotide gated channel beta 1''', also known as '''CNGB1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: CNGB1 cyclic nucleotide gated channel beta 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1258| accessdate = }}</ref>
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 {{PBB_Summary
@@ Line 55: / Line 6: @@
 | summary_text =
 }}
 ==See also==
 * [[Cyclic nucleotide-gated ion channel]]
 ==References==
-{{reflist|2}}
+{{reflist}}
 ==Further reading==
@@ Line 66: / Line 16: @@
 {{PBB_Further_reading
 | citations =
-*{{cite journal  | author=Hofmann F, Biel M, Kaupp UB |title=International Union of Pharmacology. LI. Nomenclature and structure-function relationships of cyclic nucleotide-regulated channels. |journal=Pharmacol. Rev. |volume=57 |issue= 4 |pages= 455-62 |year= 2006 |pmid= 16382102 |doi= 10.1124/pr.57.4.8 }}
+*{{cite journal  | vauthors=Hofmann F, Biel M, Kaupp UB |title=International Union of Pharmacology. LI. Nomenclature and structure-function relationships of cyclic nucleotide-regulated channels. |journal=Pharmacol. Rev. |volume=57 |issue= 4 |pages= 455–62 |year= 2006 |pmid= 16382102 |doi= 10.1124/pr.57.4.8 }}
-*{{cite journal  | author=Kondo H, Qin M, Mizota A, ''et al.'' |title=A homozygosity-based search for mutations in patients with autosomal recessive retinitis pigmentosa, using microsatellite markers. |journal=Invest. Ophthalmol. Vis. Sci. |volume=45 |issue= 12 |pages= 4433-9 |year= 2005 |pmid= 15557452 |doi= 10.1167/iovs.04-0544 }}
+*{{cite journal  | vauthors=Kondo H, Qin M, Mizota A |title=A homozygosity-based search for mutations in patients with autosomal recessive retinitis pigmentosa, using microsatellite markers. |journal=Invest. Ophthalmol. Vis. Sci. |volume=45 |issue= 12 |pages= 4433–9 |year= 2005 |pmid= 15557452 |doi= 10.1167/iovs.04-0544 |display-authors=etal}}
-*{{cite journal  | author=Trudeau MC, Zagotta WN |title=Mechanism of calcium/calmodulin inhibition of rod cyclic nucleotide-gated channels. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 12 |pages= 8424-9 |year= 2002 |pmid= 12048242 |doi= 10.1073/pnas.122015999 }}
+*{{cite journal  | vauthors=Trudeau MC, Zagotta WN |title=Mechanism of calcium/calmodulin inhibition of rod cyclic nucleotide-gated channels. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 12 |pages= 8424–9 |year= 2002 |pmid= 12048242 |doi= 10.1073/pnas.122015999  | pmc=123083 }}
-*{{cite journal  | author=Poetsch A, Molday LL, Molday RS |title=The cGMP-gated channel and related glutamic acid-rich proteins interact with peripherin-2 at the rim region of rod photoreceptor disc membranes. |journal=J. Biol. Chem. |volume=276 |issue= 51 |pages= 48009-16 |year= 2002 |pmid= 11641407 |doi= 10.1074/jbc.M108941200 }}
+*{{cite journal  | vauthors=Poetsch A, Molday LL, Molday RS |title=The cGMP-gated channel and related glutamic acid-rich proteins interact with peripherin-2 at the rim region of rod photoreceptor disc membranes. |journal=J. Biol. Chem. |volume=276 |issue= 51 |pages= 48009–16 |year= 2002 |pmid= 11641407 |doi= 10.1074/jbc.M108941200 }}
-*{{cite journal  | author=Bareil C, Hamel CP, Delague V, ''et al.'' |title=Segregation of a mutation in CNGB1 encoding the beta-subunit of the rod cGMP-gated channel in a family with autosomal recessive retinitis pigmentosa. |journal=Hum. Genet. |volume=108 |issue= 4 |pages= 328-34 |year= 2001 |pmid= 11379879 |doi=  }}
+*{{cite journal  | vauthors=Bareil C, Hamel CP, Delague V |title=Segregation of a mutation in CNGB1 encoding the beta-subunit of the rod cGMP-gated channel in a family with autosomal recessive retinitis pigmentosa. |journal=Hum. Genet. |volume=108 |issue= 4 |pages= 328–34 |year= 2001 |pmid= 11379879 |doi=10.1007/s004390100496  |display-authors=etal}}
-*{{cite journal  | author=Pogacić V, Dragon F, Filipowicz W |title=Human H/ACA small nucleolar RNPs and telomerase share evolutionarily conserved proteins NHP2 and NOP10. |journal=Mol. Cell. Biol. |volume=20 |issue= 23 |pages= 9028-40 |year= 2000 |pmid= 11074001 |doi=  }}
+*{{cite journal  | vauthors=Pogacić V, Dragon F, Filipowicz W |title=Human H/ACA small nucleolar RNPs and telomerase share evolutionarily conserved proteins NHP2 and NOP10. |journal=Mol. Cell. Biol. |volume=20 |issue= 23 |pages= 9028–40 |year= 2000 |pmid= 11074001 |doi=10.1128/MCB.20.23.9028-9040.2000  | pmc=86556  }}
-*{{cite journal  | author=Körschen HG, Beyermann M, Müller F, ''et al.'' |title=Interaction of glutamic-acid-rich proteins with the cGMP signalling pathway in rod photoreceptors. |journal=Nature |volume=400 |issue= 6746 |pages= 761-6 |year= 1999 |pmid= 10466724 |doi= 10.1038/23468 }}
+*{{cite journal  | vauthors=Körschen HG, Beyermann M, Müller F |title=Interaction of glutamic-acid-rich proteins with the cGMP signalling pathway in rod photoreceptors. |journal=Nature |volume=400 |issue= 6746 |pages= 761–6 |year= 1999 |pmid= 10466724 |doi= 10.1038/23468 |display-authors=etal}}
-*{{cite journal  | author=Ardell MD, Aragon I, Oliveira L, ''et al.'' |title=The beta subunit of human rod photoreceptor cGMP-gated cation channel is generated from a complex transcription unit. |journal=FEBS Lett. |volume=389 |issue= 2 |pages= 213-8 |year= 1996 |pmid= 8766832 |doi=  }}
+*{{cite journal  | vauthors=Ardell MD, Aragon I, Oliveira L |title=The beta subunit of human rod photoreceptor cGMP-gated cation channel is generated from a complex transcription unit. |journal=FEBS Lett. |volume=389 |issue= 2 |pages= 213–8 |year= 1996 |pmid= 8766832 |doi=10.1016/0014-5793(96)00588-1  |display-authors=etal}}
-*{{cite journal  | author=Chen TY, Peng YW, Dhallan RS, ''et al.'' |title=A new subunit of the cyclic nucleotide-gated cation channel in retinal rods. |journal=Nature |volume=362 |issue= 6422 |pages= 764-7 |year= 1993 |pmid= 7682292 |doi= 10.1038/362764a0 }}
+*{{cite journal  | vauthors=Chen TY, Peng YW, Dhallan RS |title=A new subunit of the cyclic nucleotide-gated cation channel in retinal rods. |journal=Nature |volume=362 |issue= 6422 |pages= 764–7 |year= 1993 |pmid= 7682292 |doi= 10.1038/362764a0 |display-authors=etal}}
-*{{cite journal  | author=Ardell MD, Makhija AK, Oliveira L, ''et al.'' |title=cDNA, gene structure, and chromosomal localization of human GAR1 (CNCG3L), a homolog of the third subunit of bovine photoreceptor cGMP-gated channel. |journal=Genomics |volume=28 |issue= 1 |pages= 32-8 |year= 1995 |pmid= 7590744 |doi= 10.1006/geno.1995.1102 }}
+*{{cite journal  | vauthors=Ardell MD, Makhija AK, Oliveira L |title=cDNA, gene structure, and chromosomal localization of human GAR1 (CNCG3L), a homolog of the third subunit of bovine photoreceptor cGMP-gated channel. |journal=Genomics |volume=28 |issue= 1 |pages= 32–8 |year= 1995 |pmid= 7590744 |doi= 10.1006/geno.1995.1102 |display-authors=etal}}
-*{{cite journal  | author=Chen TY, Illing M, Molday LL, ''et al.'' |title=Subunit 2 (or beta) of retinal rod cGMP-gated cation channel is a component of the 240-kDa channel-associated protein and mediates Ca(2+)-calmodulin modulation. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=91 |issue= 24 |pages= 11757-61 |year= 1994 |pmid= 7526403 |doi=  }}
+*{{cite journal  | vauthors=Chen TY, Illing M, Molday LL |title=Subunit 2 (or beta) of retinal rod cGMP-gated cation channel is a component of the 240-kDa channel-associated protein and mediates Ca(2+)-calmodulin modulation. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=91 |issue= 24 |pages= 11757–61 |year= 1994 |pmid= 7526403 |doi=10.1073/pnas.91.24.11757  | pmc=45311  |display-authors=etal}}
-*{{cite journal  | author=Fujii Y, Zhao FX, Fu SC, ''et al.'' |title=Stable preparation of aldose reductase isoenzymes from human placenta. |journal=Protein Expr. Purif. |volume=2 |issue= 5-6 |pages= 420-5 |year= 1992 |pmid= 1821816 |doi=  }}
+*{{cite journal  | vauthors=Fujii Y, Zhao FX, Fu SC |title=Stable preparation of aldose reductase isoenzymes from human placenta. |journal=Protein Expr. Purif. |volume=2 |issue= 5-6 |pages= 420–5 |year= 1992 |pmid= 1821816 |doi=10.1016/1046-5928(91)90103-P  |display-authors=etal}}
 }}
 {{refend}}
-== External links ==
+==External links==
+* [https://www.ncbi.nlm.nih.gov/books/NBK1417/  GeneReviews/NCBI/NIH/UW entry on Retinitis Pigmentosa Overview]
 * {{MeshName|CNGB1+protein,+human}}
+* {{UCSC gene info|CNGB1}}
+* {{UCSC gene info|GAR1}}
+{{Ion channels|g4}}
+<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
+{{PBB_Controls
+| update_page = yes
+| require_manual_inspection = no
+| update_protein_box = yes
+| update_summary = yes
+| update_citations = yes
+}}
+[[Category:Ion channels]]
 {{membrane-protein-stub}}
-{{Ion channels}}
-[[Category:Ion channels]]
-{{WikiDoc Sources}}

CNGB1: Difference between revisions

Latest revision as of 23:34, 21 November 2017

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See also

References

Further reading

External links

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