CACNB3
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| Calcium channel, voltage-dependent, beta 3 subunit
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| PDB rendering based on 1vyt. | ||||||||||||||
| Available structures: 1vyt, 1vyu | ||||||||||||||
| Identifiers | ||||||||||||||
| Symbol(s) | CACNB3; CACNLB3 | |||||||||||||
| External IDs | OMIM: 601958 MGI: 103307 Homologene: 20187 | |||||||||||||
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| RNA expression pattern | ||||||||||||||
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| Orthologs | ||||||||||||||
| Human | Mouse | |||||||||||||
| Entrez | 784 | 12297 | ||||||||||||
| Ensembl | ENSG00000167535 | ENSMUSG00000003352 | ||||||||||||
| Uniprot | P54284 | Q8K5A7 | ||||||||||||
| Refseq | NM_000725 (mRNA) NP_000716 (protein) | NM_001044741 (mRNA) NP_001038206 (protein) | ||||||||||||
| Location | Chr 12: 47.5 - 47.51 Mb | Chr 15: 98.46 - 98.47 Mb | ||||||||||||
| Pubmed search | [1] | [2] | ||||||||||||
Calcium channel, voltage-dependent, beta 3 subunit, also known as CACNB3, is a human gene.[1]
See also
References
Further reading
- Yamada Y, Masuda K, Li Q, et al. (1995). "The structures of the human calcium channel alpha 1 subunit (CACNL1A2) and beta subunit (CACNLB3) genes.". Genomics 27 (2): 312-9. doi:10.1006/geno.1995.1048. PMID 7557998.
- Collin T, Lory P, Taviaux S, et al. (1994). "Cloning, chromosomal location and functional expression of the human voltage-dependent calcium-channel beta 3 subunit.". Eur. J. Biochem. 220 (1): 257-62. PMID 8119293.
- Rosenfeld MR, Wong E, Dalmau J, et al. (1993). "Cloning and characterization of a Lambert-Eaton myasthenic syndrome antigen.". Ann. Neurol. 33 (1): 113-20. doi:10.1002/ana.410330126. PMID 8494331.
- Murakami M, Wissenbach U, Flockerzi V (1996). "Gene structure of the murine calcium channel beta3 subunit, cDNA and characterization of alternative splicing and transcription products.". Eur. J. Biochem. 236 (1): 138-43. PMID 8617257.
- Scott VE, De Waard M, Liu H, et al. (1996). "Beta subunit heterogeneity in N-type Ca2+ channels.". J. Biol. Chem. 271 (6): 3207-12. PMID 8621722.
- Bell DC, Butcher AJ, Berrow NS, et al. (2001). "Biophysical properties, pharmacology, and modulation of human, neuronal L-type (alpha(1D), Ca(V)1.3) voltage-dependent calcium currents.". J. Neurophysiol. 85 (2): 816-27. PMID 11160515.
- Colecraft HM, Alseikhan B, Takahashi SX, et al. (2002). "Novel functional properties of Ca(2+) channel beta subunits revealed by their expression in adult rat heart cells.". J. Physiol. (Lond.) 541 (Pt 2): 435-52. PMID 12042350.
- Murakami M, Fleischmann B, De Felipe C, et al. (2002). "Pain perception in mice lacking the beta3 subunit of voltage-activated calcium channels.". J. Biol. Chem. 277 (43): 40342-51. doi:10.1074/jbc.M203425200. PMID 12161429.
- Qin N, Yagel S, Momplaisir ML, et al. (2002). "Molecular cloning and characterization of the human voltage-gated calcium channel alpha(2)delta-4 subunit.". Mol. Pharmacol. 62 (3): 485-96. PMID 12181424.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
- Chen YH, Li MH, Zhang Y, et al. (2004). "Structural basis of the alpha1-beta subunit interaction of voltage-gated Ca2+ channels.". Nature 429 (6992): 675-80. doi:10.1038/nature02641. PMID 15170217.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
- Vendel AC, Terry MD, Striegel AR, et al. (2006). "Alternative splicing of the voltage-gated Ca2+ channel beta4 subunit creates a uniquely folded N-terminal protein binding domain with cell-specific expression in the cerebellar cortex.". J. Neurosci. 26 (10): 2635-44. doi:10.1523/JNEUROSCI.0067-06.2006. PMID 16525042.
External links
Template:Membrane-protein-stub
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
