Voltage-dependent calcium channels can be distinguished based on their voltage-dependence, deactivation, and single-channel conductance. Low-voltage-activated calcium channels are referred to as 'T' type because their currents are both transient, owing to fast inactivation, and tiny, owing to small conductance. T-type channels are thought to be involved in pacemaker activity, low-threshold calcium spikes, neuronal oscillations and resonance, and rebound burst firing.
Interactive pathway map
Click on genes, proteins and metabolites below to link to respective Wikipedia articles. [§ 1]
- The interactive pathway map can be edited at WikiPathways: "NicotineActivityonChromaffinCells_WP1603".
- "Entrez Gene: CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit".
- Perez-Reyes E, Cribbs LL, Daud A, Lacerda AE, Barclay J, Williamson MP, Fox M, Rees M, Lee JH (February 1998). "Molecular characterization of a neuronal low-voltage-activated T-type calcium channel". Nature. 391 (6670): 896–900. doi:10.1038/36110. PMID 9495342.
- Catterall WA, Perez-Reyes E, Snutch TP, Striessnig J (December 2005). "International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels". Pharmacol. Rev. 57 (4): 411–25. doi:10.1124/pr.57.4.5. PMID 16382099.
- CACNA1G+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)
- Human CACNA1G genome location and CACNA1G gene details page in the UCSC Genome Browser.
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