AQP8: Difference between revisions

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{{Infobox_gene}}
{{PBB_Controls
'''Aquaporin-8''' is a [[protein]] that in humans is encoded by the ''AQP8'' [[gene]].<ref name="pmid9806845">{{cite journal |vauthors=Koyama N, Ishibashi K, Kuwahara M, Inase N, Ichioka M, Sasaki S, Marumo F | title = Cloning and functional expression of human aquaporin8 cDNA and analysis of its gene | journal = Genomics | volume = 54 | issue = 1 | pages = 169–72 |date=Jan 1999 | pmid = 9806845 | pmc =  | doi = 10.1006/geno.1998.5552 }}</ref><ref name="pmid10393433">{{cite journal |vauthors=Viggiano L, Rocchi M, Svelto M, Calamita G | title = Assignment of the aquaporin-8 water channel gene (AQP8) to human chromosome 16p12 | journal = Cytogenet Cell Genet | volume = 84 | issue = 3–4 | pages = 208–10 |date=Jul 1999 | pmid = 10393433 | pmc =  | doi =10.1159/000015260 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: AQP8 aquaporin 8| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=343| accessdate = }}</ref>
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{{GNF_Protein_box
| image =
| image_source =
| PDB =  
| Name = Aquaporin 8
| HGNCid = 642
| Symbol = AQP8
| AltSymbols =;
| OMIM = 603750
| ECnumber =
  | Homologene = 68166
| MGIid = 1195271
| GeneAtlas_image1 = PBB_GE_AQP8_206784_at_tn.png
| Function = {{GNF_GO|id=GO:0005215 |text = transporter activity}} {{GNF_GO|id=GO:0015250 |text = water channel activity}}
| Component = {{GNF_GO|id=GO:0005886 |text = plasma membrane}} {{GNF_GO|id=GO:0005887 |text = integral to plasma membrane}}
| Process = {{GNF_GO|id=GO:0006810 |text = transport}} {{GNF_GO|id=GO:0006833 |text = water transport}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 343
    | Hs_Ensembl = ENSG00000103375
    | Hs_RefseqProtein = NP_001160
    | Hs_RefseqmRNA = NM_001169
    | Hs_GenLoc_db =   
    | Hs_GenLoc_chr = 16
    | Hs_GenLoc_start = 25135784
    | Hs_GenLoc_end = 25147752
    | Hs_Uniprot = O94778
    | Mm_EntrezGene = 11833
    | Mm_Ensembl = ENSMUSG00000030762
    | Mm_RefseqmRNA = NM_007474
    | Mm_RefseqProtein = NP_031500
    | Mm_GenLoc_db =   
    | Mm_GenLoc_chr = 7
    | Mm_GenLoc_start = 123253460
    | Mm_GenLoc_end = 123259151
    | Mm_Uniprot = P56404
  }}
}}
'''Aquaporin 8''', also known as '''AQP8''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: AQP8 aquaporin 8| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=343| accessdate = }}</ref>


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{{PBB_Summary
{{PBB_Summary
| section_title =  
| section_title =  
| summary_text = Aquaporin 8 (AQP8) is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0).  Aquaporin 8 mRNA is found in pancreas and colon but not other tissues.<ref name="entrez">{{cite web | title = Entrez Gene: AQP8 aquaporin 8| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=343| accessdate = }}</ref>
| summary_text = Aquaporin 8 (AQP8) is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0).  Aquaporin 8 mRNA is found in pancreas and colon but not other tissues.<ref name="entrez" />
}}
}}


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==References==
==References==
{{reflist|2}}
{{reflist}}


==Further reading==
==Further reading==
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{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal  | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171-4 |year= 1994 |pmid= 8125298 |doi=  }}
*{{cite journal  |vauthors=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides |journal=Gene |volume=138 |issue= 1–2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=10.1016/0378-1119(94)90802-8 }}
*{{cite journal  | author=Harrington DJ, Adachi K, Royer WE |title=The high resolution crystal structure of deoxyhemoglobin S. |journal=J. Mol. Biol. |volume=272 |issue= 3 |pages= 398-407 |year= 1997 |pmid= 9325099 |doi= 10.1006/jmbi.1997.1253 }}
*{{cite journal  |vauthors=Harrington DJ, Adachi K, Royer WE |title=The high resolution crystal structure of deoxyhemoglobin S |journal=J. Mol. Biol. |volume=272 |issue= 3 |pages= 398–407 |year= 1997 |pmid= 9325099 |doi= 10.1006/jmbi.1997.1253 }}
*{{cite journal  | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, ''et al.'' |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149-56 |year= 1997 |pmid= 9373149 |doi=  }}
*{{cite journal  | author=Suzuki Y |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library |journal=Gene |volume=200 |issue= 1–2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=10.1016/S0378-1119(97)00411-3 |name-list-format=vanc| author2=Yoshitomo-Nakagawa K  | author3=Maruyama K  | display-authors=3 | last4=Suyama  | first4=A  | last5=Sugano  | first5=S }}
*{{cite journal  | author=Koyama N, Ishibashi K, Kuwahara M, ''et al.'' |title=Cloning and functional expression of human aquaporin8 cDNA and analysis of its gene. |journal=Genomics |volume=54 |issue= 1 |pages= 169-72 |year= 1999 |pmid= 9806845 |doi= 10.1006/geno.1998.5552 }}
*{{cite journal  |vauthors=Fischer H, Stenling R, Rubio C, Lindblom A |title=Differential expression of Aquaporin 8 in human colonic epithelial cells and colorectal tumors |journal=BMC Physiol. |volume=1|pages= 1 |year= 2003 |pmid= 11231887 |doi=10.1186/1472-6793-1-1  | pmc=32180 }}
*{{cite journal | author=Viggiano L, Rocchi M, Svelto M, Calamita G |title=Assignment of the aquaporin-8 water channel gene (AQP8) to human chromosome 16p12. |journal=Cytogenet. Cell Genet. |volume=84 |issue= 3-4 |pages= 208-10 |year= 1999 |pmid= 10393433 |doi=  }}
*{{cite journal  | author=Harrington JJ |title=Creation of genome-wide protein expression libraries using random activation of gene expression |journal=Nat. Biotechnol. |volume=19 |issue= 5 |pages= 440–5 |year= 2001 |pmid= 11329013 |doi= 10.1038/88107 |name-list-format=vanc| author2=Sherf B  | author3=Rundlett S  | display-authors=3  | last4=Jackson  | first4=P. David  | last5=Perry  | first5=Rob  | last6=Cain  | first6=Scott  | last7=Leventhal  | first7=Christina  | last8=Thornton  | first8=Mark  | last9=Ramachandran  | first9=Rakesh }}
*{{cite journal  | author=Fischer H, Stenling R, Rubio C, Lindblom A |title=Differential expression of aquaporin 8 in human colonic epithelial cells and colorectal tumors. |journal=BMC Physiol. |volume=1 |issue=  |pages= 1 |year= 2003 |pmid= 11231887 |doi=  }}
*{{cite journal  | author=Wang S |title=Expression of aquaporin-8 in human placenta and chorioamniotic membranes: evidence of molecular mechanism for intramembranous amniotic fluid resorption |journal=Am. J. Obstet. Gynecol. |volume=185 |issue= 5 |pages= 1226–31 |year= 2001 |pmid= 11717661 |doi= 10.1067/mob.2001.117971 |name-list-format=vanc| author2=Kallichanda N  | author3=Song W  | display-authors=3  | last4=Ramirez  | first4=BA  | last5=Ross  | first5=MG }}
*{{cite journal  | author=Harrington JJ, Sherf B, Rundlett S, ''et al.'' |title=Creation of genome-wide protein expression libraries using random activation of gene expression. |journal=Nat. Biotechnol. |volume=19 |issue= 5 |pages= 440-5 |year= 2001 |pmid= 11329013 |doi= 10.1038/88107 }}
*{{cite journal  | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241  |name-list-format=vanc| author2=Feingold EA  | author3=Grouse LH  | display-authors=3  | last4=Derge  | first4=JG  | last5=Klausner  | first5=RD  | last6=Collins  | first6=FS  | last7=Wagner  | first7=L  | last8=Shenmen  | first8=CM  | last9=Schuler  | first9=GD }}
*{{cite journal  | author=Wang S, Kallichanda N, Song W, ''et al.'' |title=Expression of aquaporin-8 in human placenta and chorioamniotic membranes: evidence of molecular mechanism for intramembranous amniotic fluid resorption. |journal=Am. J. Obstet. Gynecol. |volume=185 |issue= 5 |pages= 1226-31 |year= 2001 |pmid= 11717661 |doi= 10.1067/mob.2001.117971 }}
*{{cite journal  |vauthors=Wang S, Chen J, Au KT, Ross MG |title=Expression of aquaporin 8 and its up-regulation by cyclic adenosine monophosphate in human WISH cells |journal=Am. J. Obstet. Gynecol. |volume=188 |issue= 4 |pages= 997–1001 |year= 2003 |pmid= 12712100 |doi=10.1067/mob.2003.214 }}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | author=Gerhard DS |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928  |name-list-format=vanc| author2=Wagner L  | author3=Feingold EA  | display-authors=3  | last4=Shenmen  | first4=CM  | last5=Grouse  | first5=LH  | last6=Schuler  | first6=G  | last7=Klein  | first7=SL  | last8=Old  | first8=S  | last9=Rasooly  | first9=R }}
*{{cite journal  | author=Wang S, Chen J, Au KT, Ross MG |title=Expression of aquaporin 8 and its up-regulation by cyclic adenosine monophosphate in human WISH cells. |journal=Am. J. Obstet. Gynecol. |volume=188 |issue= 4 |pages= 997-1001 |year= 2003 |pmid= 12712100 |doi=  }}
*{{cite journal  | author=Zahn A |title=Aquaporin-8 expression is reduced in ileum and induced in colon of patients with ulcerative colitis |journal=World J. Gastroenterol. |volume=13 |issue= 11 |pages= 1687–95 |year= 2007 |pmid= 17461471 |doi= |name-list-format=vanc| author2=Moehle C  | author3=Langmann T  | display-authors=3  | last4=Ehehalt  | first4=R  | last5=Autschbach  | first5=F  | last6=Stremmel  | first6=W  | last7=Schmitz  | first7=G }}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal  | author=Zahn A, Moehle C, Langmann T, ''et al.'' |title=Aquaporin-8 expression is reduced in ileum and induced in colon of patients with ulcerative colitis. |journal=World J. Gastroenterol. |volume=13 |issue= 11 |pages= 1687-95 |year= 2007 |pmid= 17461471 |doi=  }}
}}
}}
{{refend}}
{{refend}}
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== External links ==
== External links ==
* {{MeshName|AQP8+protein,+human}}
* {{MeshName|AQP8+protein,+human}}
* {{UCSC gene info|AQP8}}


{{membrane-protein-stub}}
{{membrane-protein-stub}}
{{NLM content}}
{{NLM content}}
{{Ion channels}}
{{Ion channels|g4}}
{{WikiDoc Sources}}
 
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Latest revision as of 18:10, 29 August 2017

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Identifiers
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External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
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Wikidata
View/Edit Human

Aquaporin-8 is a protein that in humans is encoded by the AQP8 gene.[1][2][3]

Aquaporin 8 (AQP8) is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). Aquaporin 8 mRNA is found in pancreas and colon but not other tissues.[3]

See also

References

  1. ↑ Koyama N, Ishibashi K, Kuwahara M, Inase N, Ichioka M, Sasaki S, Marumo F (Jan 1999). "Cloning and functional expression of human aquaporin8 cDNA and analysis of its gene". Genomics. 54 (1): 169–72. doi:10.1006/geno.1998.5552. PMID 9806845.
  2. ↑ Viggiano L, Rocchi M, Svelto M, Calamita G (Jul 1999). "Assignment of the aquaporin-8 water channel gene (AQP8) to human chromosome 16p12". Cytogenet Cell Genet. 84 (3–4): 208–10. doi:10.1159/000015260. PMID 10393433.
  3. ↑ 3.0 3.1 "Entrez Gene: AQP8 aquaporin 8".

Further reading

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


Retrieved from "https://www.wikidoc.org/index.php?title=AQP8&oldid=1417378"