TRPC6

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Transient receptor potential cation channel, subfamily C, member 6
Identifiers
Symbols TRPC6 ; FLJ11098; FLJ14863; FSGS2; TRP6
External IDs Template:OMIM5 Template:MGI HomoloGene37944
Orthologs
Template:GNF Ortholog box
Species Human Mouse
Entrez n/a n/a
Ensembl n/a n/a
UniProt n/a n/a
RefSeq (mRNA) n/a n/a
RefSeq (protein) n/a n/a
Location (UCSC) n/a n/a
PubMed search n/a n/a

Transient receptor potential cation channel, subfamily C, member 6, also known as TRPC6, is a human gene.


TRPC6 is a transient receptor potential ion channel associated with focal segmental glomerulosclerosis.[1]

References

  1. Winn MP, Conlon PJ, Lynn KL; et al. (2005). "A mutation in the TRPC6 cation channel causes familial focal segmental glomerulosclerosis". Science. 308 (5729): 1801–4. doi:10.1126/science.1106215. PMID 15879175.


Further reading

  • Heiner I, Eisfeld J, Lückhoff A (2004). "Role and regulation of TRP channels in neutrophil granulocytes". Cell Calcium. 33 (5–6): 533–40. PMID 12765698.
  • Walz G (2006). "Slit or pore? A mutation of the ion channel TRPC6 causes FSGS". Nephrol. Dial. Transplant. 20 (9): 1777–9. doi:10.1093/ndt/gfh961. PMID 15998650.
  • Clapham DE, Julius D, Montell C, Schultz G (2006). "International Union of Pharmacology. XLIX. Nomenclature and structure-function relationships of transient receptor potential channels". Pharmacol. Rev. 57 (4): 427–50. doi:10.1124/pr.57.4.6. PMID 16382100.
  • Schlöndorff JS, Pollak MR (2007). "TRPC6 in glomerular health and disease: what we know and what we believe". Semin. Cell Dev. Biol. 17 (6): 667–74. doi:10.1016/j.semcdb.2006.11.003. PMID 17116414.
  • Dietrich A, Gudermann T (2007). "TRPC6". Handb Exp Pharmacol (179): 125–41. doi:10.1007/978-3-540-34891-7_7. PMID 17217054.


External links


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