TRPC6
Transient receptor potential cation channel, subfamily C, member 6 | |||||||||||
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Identifiers | |||||||||||
Symbols | TRPC6 ; FLJ11098; FLJ14863; FSGS2; TRP6 | ||||||||||
External IDs | Template:OMIM5 Template:MGI HomoloGene: 37944 | ||||||||||
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Species | Human | Mouse | |||||||||
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RefSeq (mRNA) | n/a | n/a | |||||||||
RefSeq (protein) | n/a | n/a | |||||||||
Location (UCSC) | n/a | n/a | |||||||||
PubMed search | n/a | n/a |
Transient receptor potential cation channel, subfamily C, member 6, also known as TRPC6, is a human gene.
TRPC6 is a transient receptor potential ion channel associated with focal segmental glomerulosclerosis.[1]
References
- ↑ Winn MP, Conlon PJ, Lynn KL; et al. (2005). "A mutation in the TRPC6 cation channel causes familial focal segmental glomerulosclerosis". Science. 308 (5729): 1801–4. doi:10.1126/science.1106215. PMID 15879175.
Further reading
- Heiner I, Eisfeld J, Lückhoff A (2004). "Role and regulation of TRP channels in neutrophil granulocytes". Cell Calcium. 33 (5–6): 533–40. PMID 12765698.
- Walz G (2006). "Slit or pore? A mutation of the ion channel TRPC6 causes FSGS". Nephrol. Dial. Transplant. 20 (9): 1777–9. doi:10.1093/ndt/gfh961. PMID 15998650.
- Clapham DE, Julius D, Montell C, Schultz G (2006). "International Union of Pharmacology. XLIX. Nomenclature and structure-function relationships of transient receptor potential channels". Pharmacol. Rev. 57 (4): 427–50. doi:10.1124/pr.57.4.6. PMID 16382100.
- Schlöndorff JS, Pollak MR (2007). "TRPC6 in glomerular health and disease: what we know and what we believe". Semin. Cell Dev. Biol. 17 (6): 667–74. doi:10.1016/j.semcdb.2006.11.003. PMID 17116414.
- Dietrich A, Gudermann T (2007). "TRPC6". Handb Exp Pharmacol (179): 125–41. doi:10.1007/978-3-540-34891-7_7. PMID 17217054.
External links
- TRPC6+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)
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