Thymoma history and symptoms: Difference between revisions
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==Overview== | ==Overview== | ||
A third of all people with a thymoma have symptoms due to compression of the surrounding organs by an expansive mass. This may take the form of [[vena cava superior syndrome]] (compression of the [[vena cava superior|upper caval vein]]), [[dysphagia]] (difficulty swallowing), [[cough]] or [[chest pain]]. | A third of all people with a thymoma have symptoms due to compression of the surrounding organs by an expansive mass. This may take the form of [[vena cava superior syndrome]] (compression of the [[vena cava superior|upper caval vein]]), [[dysphagia]] (difficulty swallowing), [[cough]] or [[chest pain]].<ref name="pmid10561285">{{cite journal |author=Thomas CR, Wright CD, Loehrer PJ |title=Thymoma: state of the art |journal=[[Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology]] |volume=17 |issue=7 |pages=2280–9 |year=1999 |month=July |pmid=10561285 |doi= |url=http://www.jco.org/cgi/pmidlookup?view=long&pmid=10561285 |accessdate=2012-01-18}}</ref> | ||
A third have a thymoma detected because they have an associated [[autoimmune disorder]]. The most common condition in this group is [[myasthenia gravis]] (of which 25-50% are associated with a thymoma); patients with myasthenia are routinely screened for thymoma. Other associated autoimmune conditions are [[pure red cell aplasia]] and Good's syndrome (thymoma with [[combined immunodeficiency]] and hypoimmunoglobulinemia G). Rare associations that have been reported are: [[acute pericarditis]], [[Addison's disease]], [[agranulocytosis]], [[alopecia areata]], [[ulcerative colitis]], [[Cushing's disease]], [[hemolytic anemia]], limbic encephalopathy, [[myocarditis]], [[nephrotic syndrome]], [[panhypopituitarism]], [[pernicious anemia]], [[polymyositis]], [[rheumatoid arthritis]], [[sarcoidosis]], [[scleroderma]], sensorimotor radiculopathy, ''[[stiff person syndrome]]'', [[systemic lupus erythematosus]] and [[thyroiditis]]. | A third have a thymoma detected because they have an associated [[autoimmune disorder]]. The most common condition in this group is [[myasthenia gravis]] (of which 25-50% are associated with a thymoma); patients with myasthenia are routinely screened for thymoma. Other associated autoimmune conditions are [[pure red cell aplasia]] and Good's syndrome (thymoma with [[combined immunodeficiency]] and hypoimmunoglobulinemia G). Rare associations that have been reported are: [[acute pericarditis]], [[Addison's disease]], [[agranulocytosis]], [[alopecia areata]], [[ulcerative colitis]], [[Cushing's disease]], [[hemolytic anemia]], limbic encephalopathy, [[myocarditis]], [[nephrotic syndrome]], [[panhypopituitarism]], [[pernicious anemia]], [[polymyositis]], [[rheumatoid arthritis]], [[sarcoidosis]], [[scleroderma]], sensorimotor radiculopathy, ''[[stiff person syndrome]]'', [[systemic lupus erythematosus]] and [[thyroiditis]].<ref name="pmid10561285">{{cite journal |author=Thomas CR, Wright CD, Loehrer PJ |title=Thymoma: state of the art |journal=[[Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology]] |volume=17 |issue=7 |pages=2280–9 |year=1999 |month=July |pmid=10561285 |doi= |url=http://www.jco.org/cgi/pmidlookup?view=long&pmid=10561285 |accessdate=2012-01-18}}</ref> | ||
A third to half of all people with a thymoma have no symptoms at all, and the mass is identified on a [[chest X-ray]] performed for an unrelated problem. | A third to half of all people with a thymoma have no symptoms at all, and the mass is identified on a [[chest X-ray]] performed for an unrelated problem.<ref name="pmid10561285">{{cite journal |author=Thomas CR, Wright CD, Loehrer PJ |title=Thymoma: state of the art |journal=[[Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology]] |volume=17 |issue=7 |pages=2280–9 |year=1999 |month=July |pmid=10561285 |doi= |url=http://www.jco.org/cgi/pmidlookup?view=long&pmid=10561285 |accessdate=2012-01-18}}</ref> | ||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
Revision as of 19:00, 18 January 2012
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Overview
A third of all people with a thymoma have symptoms due to compression of the surrounding organs by an expansive mass. This may take the form of vena cava superior syndrome (compression of the upper caval vein), dysphagia (difficulty swallowing), cough or chest pain.[1]
A third have a thymoma detected because they have an associated autoimmune disorder. The most common condition in this group is myasthenia gravis (of which 25-50% are associated with a thymoma); patients with myasthenia are routinely screened for thymoma. Other associated autoimmune conditions are pure red cell aplasia and Good's syndrome (thymoma with combined immunodeficiency and hypoimmunoglobulinemia G). Rare associations that have been reported are: acute pericarditis, Addison's disease, agranulocytosis, alopecia areata, ulcerative colitis, Cushing's disease, hemolytic anemia, limbic encephalopathy, myocarditis, nephrotic syndrome, panhypopituitarism, pernicious anemia, polymyositis, rheumatoid arthritis, sarcoidosis, scleroderma, sensorimotor radiculopathy, stiff person syndrome, systemic lupus erythematosus and thyroiditis.[1]
A third to half of all people with a thymoma have no symptoms at all, and the mass is identified on a chest X-ray performed for an unrelated problem.[1]
References
- ↑ 1.0 1.1 1.2 Thomas CR, Wright CD, Loehrer PJ (1999). "Thymoma: state of the art". Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 17 (7): 2280–9. PMID 10561285. Retrieved 2012-01-18. Unknown parameter
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