Tetralogy of fallot causes: Difference between revisions

Jump to navigation Jump to search
No edit summary
No edit summary
 
(33 intermediate revisions by 8 users not shown)
Line 1: Line 1:
__NOTOC__
{{Tetralogy of fallot}}
{{Tetralogy of fallot}}
{{CMG}}; '''Associate Editors-In-Chief:''' {{Fs}}, [[Priyamvada Singh| Priyamvada Singh, M.B.B.S.]] [mailto:psingh13579@gmail.com], [[User:KeriShafer|Keri Shafer, M.D.]] [mailto:kshafer@bidmc.harvard.edu]; '''Assistant Editor-In-Chief:''' [[Kristin Feeney|Kristin Feeney, B.S.]] [mailto:kfeeney@elon.edu]
==Overview==
Common causes of tetralogy of Fallot may include: [[Alcoholism]] in the mother, [[diabetes]], [[pregnancy]] after the age of 40, [[rubella]] or other [[viral]] illnesses during [[pregnancy]], [[phenylketonuria]] ([[PKU]]) in the mother, [[fetal hydantoin syndrome]], and [[Fetus|fetal]] [[carbamazepine]] [[syndrome]].


{{CMG}}
==Causes==


'''Associate Editors-In-Chief:''' [[User:KeriShafer|Keri Shafer, M.D.]] [mailto:kshafer@bidmc.harvard.edu]; Atif Mohammad, M.D., [[Priyamvada Singh]], [[MBBS]]
=== Common Causes ===
Common causes of tetralogy of Fallot may include:


*[[Alcoholism]] in the mother
*[[Diabetes]]
*[[Pregnancy]] after the age of 40
*[[Rubella]] or other [[viral]] illnesses during pregnancy
*[[Phenylketonuria]] ([[PKU]]) in the mother
*[[Fetal hydantoin syndrome]]
* Fetal carbamazepine syndrome


=== Less Common Causes ===
Less common causes of tetralogy of Fallot may include:


[[Embryology]] studies show that it is a result of anterior malalignment of the conal septum, resulting in the clinical combination of a VSD, pulmonary stenosis, and an overriding aorta. Right ventricular hypertrophy results from this combination, which causes resistance to blood flow from the right ventricle.
* [[Clomifene]]
* Poor nutrition during pregnancy


The cause of most congenital heart defects is unknown. Many factors seem to be involved.
=== Genetic Causes ===
Genetic causes of tetralogy of Fallot may include:


Factors that increase the risk for this condition during pregnancy include:
* There is a high [[incidence]] of [[chromosomal disorder]]s in children with tetralogy of Fallot.<ref>Marinho C, Alho I, Guerra A, Rego C, Areias J, Bicho M. The methylenetetrahydrofolate reductase gene variant (C677T) as a susceptibility gene for tetralogy of Fallot. Rev Port Cardiol. Jul-Aug 2009;28(7-8):809-12.</ref><ref>Lee CN, Su YN, Cheng WF, Lin MT, Wang JK, Wu MH, et al. Association of the C677T methylenetetrahydrofolate reductase mutation with congenital heart diseases. Acta Obstet Gynecol Scand. Dec 2005;84(12):1134-40.</ref>
* Tetralogy of Fallot is associated with:


* Alcoholism in the mother
:*[[Down syndrome]]
* Diabetes
:*[[DiGeorge syndrome]] (a 22q11.2 deletion, a condition associated with heart defects, [[hypocalcemia]], and [[immune deficiency]]) A gene polymorphism at the [[methylenetetrahydrofolate reductase]] ([[MTHFR]]) region has been associated with tetralogy of Fallot.
* Mother who is over 40 years old
* Poor nutrition during pregnancy
* Rubella or other viral illnesses during pregnancy
 
* There is a high incidence of chromosomal disorders in children with tetralogy of Fallot, such as Down syndrome and DiGeorge syndrome (a condition that causes heart defects, low calcium levels, and immune deficiency).
 
==See also==
* [[Trilogy of Fallot]]
* Pentalogy of Fallot


==References==
==References==
{{Reflist|2}}
{{reflist|2}}
 
==External links==
* [http://heartcenter.seattlechildrens.org/conditions_treated/tetralogy_of_fallot.asp Tetralogy of Fallot information] from Seattle Children's Hospital Heart Center
* [http://www.med.umich.edu/cvc/mchc/partet.htm Information] by University of Michigan Health System
* [http://www-medlib.med.utah.edu/WebPath/CVHTML/CV102.html Diagram of the condition]
* [http://www.achaheart.org/resource/icon_cheartdefects_tdf.php Information for adults with ToF] from the Adult Congenital Heart Association
* [http://www.geocities.com/tet_of_fallot1/welcomepage.html Michael Warman's Website on ToF]
 
{{Congenital malformations and deformations of circulatory system}}
{{Electrocardiography}}
{{SIB}}
 
[[de:Fallot-Tetralogie]]
[[fr:Tétralogie de Fallot]]
[[it:Tetralogia di Fallot]]
[[nl:Tetralogie van Fallot]]
[[nn:Fallots tetrade]]
[[ja:ファロー四徴症]]
[[pl:Tetralogia Fallota]]
[[ru:Тетрада Фалло]]
[[uk:Тетрада Фалло]]
[[zh:法乐氏四联症]]
 


[[Category:Cardiology]]
[[Category:Cardiology]]
[[Category:Congenital heart disease]]
[[Category:Congenital heart disease]]
[[Category:Pediatrics]]
[[Category:Disease]]
[[Category:Needs causes]]


{{WikiDoc Help Menu}}
{{WikiDoc Help Menu}}
{{WikiDoc Sources}}
{{WikiDoc Sources}}

Latest revision as of 01:43, 23 February 2020

Tetralogy of fallot Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Tetalogy of Fallot from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural history, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

Chest X Ray

Echocardiography

CT

MRI

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Interventions

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

ACC/AHA Guidelines for Evaluation and Follow-up


Tetralogy of fallot causes On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Tetralogy of fallot causes

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Tetralogy of fallot causes

CDC on Tetralogy of fallot causes

Tetralogy of fallot causes in the news

Blogs on Tetralogy of fallot causes

Directions to Hospitals Treating Type page name here

Risk calculators and risk factors for Tetralogy of fallot causes

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editors-In-Chief: Fahimeh Shojaei, M.D., Priyamvada Singh, M.B.B.S. [2], Keri Shafer, M.D. [3]; Assistant Editor-In-Chief: Kristin Feeney, B.S. [4]

Overview

Common causes of tetralogy of Fallot may include: Alcoholism in the mother, diabetes, pregnancy after the age of 40, rubella or other viral illnesses during pregnancy, phenylketonuria (PKU) in the mother, fetal hydantoin syndrome, and fetal carbamazepine syndrome.

Causes

Common Causes

Common causes of tetralogy of Fallot may include:

Less Common Causes

Less common causes of tetralogy of Fallot may include:

Genetic Causes

Genetic causes of tetralogy of Fallot may include:

References

  1. Marinho C, Alho I, Guerra A, Rego C, Areias J, Bicho M. The methylenetetrahydrofolate reductase gene variant (C677T) as a susceptibility gene for tetralogy of Fallot. Rev Port Cardiol. Jul-Aug 2009;28(7-8):809-12.
  2. Lee CN, Su YN, Cheng WF, Lin MT, Wang JK, Wu MH, et al. Association of the C677T methylenetetrahydrofolate reductase mutation with congenital heart diseases. Acta Obstet Gynecol Scand. Dec 2005;84(12):1134-40.


Template:WikiDoc Sources