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==Historical Perspective==
==Historical Perspective==
===Discovery===
===Discovery===
*[Disease name] was first discovered by [name of scientist], a [nationality + occupation], in [year]/during/following [event].
*Pneumonia was first discovered by Hippocrates.
*In 1817, Dr. Simpson of United Kingdom was the first to report a case of pneumonia treated with blood letting.<ref name="pmid29257545">{{cite journal| author=| title=Case ofPneumonia, Where the Extent to Which Blood-Letting May Be Successfully Carried Is Fully Exemplified. | journal=Med Chir J Rev | year= 1817 | volume= 4 | issue= 24 | pages= 460-463 | pmid=29257545 | doi= | pmc=5570882 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29257545  }} </ref> 
*In 1842, Dr. Edward Newfold of United Kingdom was the first to report a case of typhoid pneumonia.<ref name="pmid21373079">{{cite journal| author=Newbold E| title=Case of Typhoid Pneumonia. | journal=Prov Med J Retrosp Med Sci | year= 1842 | volume= 4 | issue= 84 | pages= 87 | pmid=21373079 | doi= | pmc=2489819 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21373079  }} </ref>
*In 1875, Dr. Edwin Klebs was the first to discover the association between bacteia and the development of pneumonia.


*The association between [important risk factor/cause] and [disease name] was made in/during [year/event].
*In [year], [scientist] was the first to discover the association between [risk factor] and the development of [disease name].
*In [year], [gene] mutations were first implicated in the pathogenesis of [disease name].


==References==
==References==

Revision as of 20:00, 5 March 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Hamid Qazi, MD, BSc [2], Serge Korjian M.D., Priyamvada Singh, M.D. [3]

Overview

The pneumonia syndrome has been recognized since ancient times. It was initally described by Hippocrates who recorded his observations of its symptoms and complications. Edwin Klebs was the first to identify bacteria in the lungs of patients who died from pneumonia in 1875. This discovery was soon-after substantiated by the works of Carl Friedländer and Albert Fränkel who were the first to identify Streptococcus pneumoniae as a causative agent. The introduction of the gram stain subsequently led to the discovery of other causative organisms. Despite being an important cause of mortality before the late twentieth century, the advent of antibiotics, modern surgical techniques, and vaccination drastically lowered the morbidity and mortality of pneumonia with the turn of the century.

Historical Perspective

Discovery

  • Pneumonia was first discovered by Hippocrates.
  • In 1817, Dr. Simpson of United Kingdom was the first to report a case of pneumonia treated with blood letting.[1]
  • In 1842, Dr. Edward Newfold of United Kingdom was the first to report a case of typhoid pneumonia.[2]
  • In 1875, Dr. Edwin Klebs was the first to discover the association between bacteia and the development of pneumonia.


References

  1. "Case ofPneumonia, Where the Extent to Which Blood-Letting May Be Successfully Carried Is Fully Exemplified". Med Chir J Rev. 4 (24): 460–463. 1817. PMC 5570882. PMID 29257545.
  2. Newbold E (1842). "Case of Typhoid Pneumonia". Prov Med J Retrosp Med Sci. 4 (84): 87. PMC 2489819. PMID 21373079.

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