Pelvic inflammatory disease laboratory findings: Difference between revisions

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{{Pelvic inflammatory disease}}
{{Pelvic inflammatory disease}}
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==Overview==
==Overview==
No single test has adequate [[sensitivity]] and [[specificity]] to diagnose pelvic inflammatory disease. Laboratory findings that look for signs of [[infection]] include [[C-reactive protein]] ([[CRP]]), [[erythrocyte sedimentation rate]] ([[ESR]]), and [[WBC]] count. A sensitive serum pregnancy test should be obtained to rule out ectopic pregnancy. Gram-stain/smear becomes important in identification of rare and possibly more serious organisms.
There is no specific laboratory findings for PID. Elevated [[ESR]] and [[CRP]] are suggestive for diagnosis but are not specific. [[Nucleic acid test|NAAT]] must be performed to confirm the presence of [[Neisseria gonorrhoeae|N. gonorrhoeae]] and/or [[Chlamydia trachomatis|C. trachomatis]].


==Laboratory findings==
*There is no specific laboratory findings for PID. Elevated [[CRP]] and [[ESR]] are non specific findings. [[Leukocytosis]] is another findings.
*Laboratory confirmation of [[Chlamydia]], [[Gonorrhea]] and/or [[Mycoplasma genitalium]] in cervical discharge is helpful to guide treatment.<ref name="pmid26042815">{{cite journal |vauthors=Workowski KA, Bolan GA |title=Sexually transmitted diseases treatment guidelines, 2015 |journal=MMWR Recomm Rep |volume=64 |issue=RR-03 |pages=1–137 |year=2015 |pmid=26042815 |doi= |url=}}</ref>
*All patients with suspected pelvic inflammatory disease should undergo cervical or vaginal [[Nucleic acid amplification technique|nucleic acid amplification tests]] for [[N. gonorrhoeae]] and [[Chlamydia trachomatis|C. trachomatis]] infection.<ref name="pmid25992748">{{cite journal |vauthors=Brunham RC, Gottlieb SL, Paavonen J |title=Pelvic inflammatory disease |journal=N. Engl. J. Med. |volume=372 |issue=21 |pages=2039–48 |year=2015 |pmid=25992748 |doi=10.1056/NEJMra1411426 |url=}}</ref>
*Vaginal fluid should be evaluated for increased numbers of [[White blood cells|white cells]] (more than one [[neutrophil]] per [[Epithelial cells|epithelial cell]]) and signs of [[bacterial vaginosis]].<ref name="pmid25992748">{{cite journal |vauthors=Brunham RC, Gottlieb SL, Paavonen J |title=Pelvic inflammatory disease |journal=N. Engl. J. Med. |volume=372 |issue=21 |pages=2039–48 |year=2015 |pmid=25992748 |doi=10.1056/NEJMra1411426 |url=}}</ref>
*[[Pregnancy]] test should be routinely requested to help rule out [[ectopic pregnancy]].
*[[Serology|Serologic]] testing for [[Human Immunodeficiency Virus (HIV)|human immunodeficiency virus (HIV]]) should be performed.<ref name="pmid25992748">{{cite journal |vauthors=Brunham RC, Gottlieb SL, Paavonen J |title=Pelvic inflammatory disease |journal=N. Engl. J. Med. |volume=372 |issue=21 |pages=2039–48 |year=2015 |pmid=25992748 |doi=10.1056/NEJMra1411426 |url=}}</ref>
==References==
==References==
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{{reflist|2}}
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[[Category:Emergency mdicine]]
[[Category:Disease]]
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[[Category:Infectious disease]]
[[Category:Infectious disease]]
[[Category:Gynecology]]
[[Category:Gynecology]]
[[Category:Abdominal pain]][[Category:Sexually transmitted diseases]]
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Latest revision as of 23:37, 29 July 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Seyedmahdi Pahlavani, M.D. [2]

Overview

There is no specific laboratory findings for PID. Elevated ESR and CRP are suggestive for diagnosis but are not specific. NAAT must be performed to confirm the presence of N. gonorrhoeae and/or C. trachomatis.

Laboratory findings

References

  1. Workowski KA, Bolan GA (2015). "Sexually transmitted diseases treatment guidelines, 2015". MMWR Recomm Rep. 64 (RR-03): 1–137. PMID 26042815.
  2. 2.0 2.1 2.2 Brunham RC, Gottlieb SL, Paavonen J (2015). "Pelvic inflammatory disease". N. Engl. J. Med. 372 (21): 2039–48. doi:10.1056/NEJMra1411426. PMID 25992748.

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