Non small cell lung cancer history and symptoms: Difference between revisions

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==History==
==History==
*Obtaining the history is an important aspect of making a diagnosis of non-small cell lung cancer. It provides insight into natural evolution of the disease. Complete history will help determine the likelihood of metastases and the association with other conditions. Specific symptoms description such as duration, onset, and progression are important for making the diagnosis. Specific areas of focus when obtaining the history, are outlined below:<ref name="pmid11899115">{{cite journal |vauthors=Kaerlev L, Teglbjaerg PS, Sabroe S, Kolstad HA, Ahrens W, Eriksson M, Guénel P, Gorini G, Hardell L, Cyr D, Zambon P, Stang A, Olsen J |title=The importance of smoking and medical history for development of small bowel carcinoid tumor: a European population-based case-control study |journal=Cancer Causes Control |volume=13 |issue=1 |pages=27–34 |year=2002 |pmid=11899115 |doi= |url=}}</ref><ref name="pain">Non small cell lung cancer. Wikipedia. https://en.wikipedia.org/wiki/Non-small-cell_lung_carcinoma Accessed on February 24, 2016 </ref><ref name="pmid17505036">{{cite journal |vauthors=Raz DJ, Zell JA, Ou SH, Gandara DR, Anton-Culver H, Jablons DM |title=Natural history of stage I non-small cell lung cancer: implications for early detection |journal=Chest |volume=132 |issue=1 |pages=193–9 |year=2007 |pmid=17505036 |doi=10.1378/chest.06-3096 |url=}}</ref>
Obtaining the history is an important aspect of making a diagnosis of non-small cell lung cancer.  
 
* Past medical, social and family history provides important insight into natural evolution of the disease.
*Family history of cancer
* Complete history will help determine the likelihood of metastases and the association with other conditions.  
*Personal history of cancer
* Specific areas of focus when obtaining the history, are outlined below:<ref name="pmid11899115">{{cite journal |vauthors=Kaerlev L, Teglbjaerg PS, Sabroe S, Kolstad HA, Ahrens W, Eriksson M, Guénel P, Gorini G, Hardell L, Cyr D, Zambon P, Stang A, Olsen J |title=The importance of smoking and medical history for development of small bowel carcinoid tumor: a European population-based case-control study |journal=Cancer Causes Control |volume=13 |issue=1 |pages=27–34 |year=2002 |pmid=11899115 |doi= |url=}}</ref><ref name="pmid17505036">{{cite journal |vauthors=Raz DJ, Zell JA, Ou SH, Gandara DR, Anton-Culver H, Jablons DM |title=Natural history of stage I non-small cell lung cancer: implications for early detection |journal=Chest |volume=132 |issue=1 |pages=193–9 |year=2007 |pmid=17505036 |doi=10.1378/chest.06-3096 |url=}}</ref>
:*[[Colorectal cancer]]
** '''Past medical history:'''
:*[[Bladder cancer]]  
*** Previous primary infection of [[tuberculosis]]
:*[[Breast cancer]]
*** [[Colorectal cancer]]
:*[[Prostate cancer]]
***[[Bladder cancer]]  
*Positive history of active/passive smoking
***[[Breast cancer]]
:*Number of cigarettes/year  
***[[Prostate cancer]]
:*Number of years/months of active smoking
**'''Social history:'''
:*Number of years/months of [[smoking cessation]]  
***Positive history of active/passive smoking
*Previous primary infection of [[tuberculosis]]
***Number of cigarettes/year
*Positive family history of the following syndromes:
***Number of years/months of active smoking
:*[[Li-Fraumeni syndrome]]  
***Number of years/months of [[smoking cessation]]  
:*[[Noonan syndrome]]
**'''Family history:'''
***Positive family history for cancer
***Positive family history for following syndromes:
****[[Li-Fraumeni syndrome]]  
****[[Noonan syndrome]]


==Common Symptoms==
==Common Symptoms==
*The majority of non-small cell lung cancers are [[asymptomatic]] and are usually found incidentally.<ref name="pain">Non small cell lung cancer. Wikipedia. https://en.wikipedia.org/wiki/Non-small-cell_lung_carcinoma Accessed on February 24, 2016 </ref>
The majority of non-small cell lung cancers are [[asymptomatic]] and are usually found incidentally. The hallmark of non-small cell lung cancer is chronic cough, weight loss, and hemoptysis.<ref name="Hamilton">{{cite journal | last =Hamilton | first =W | coauthors =  Peters TJ, Round A, Sharp D | title =What are the clinical features of lung cancer before the diagnosis is made? A population based case-control study | journal =Thorax | volume =60 | issue=12 | pages =1059–1065 | publisher = BMJ Publishing Group Ltd. | date =Dec 2005 | pmid =16227326 }}</ref><ref name="canadian">Lung cancer. Canadian Cancer Society 2015. http://www.cancer.ca/en/cancer-information/cancer-type/lung/signs-and-symptoms/?region=ab Accessed on February 24, 2015</ref>
*The hallmark of non-small cell lung cancer is chronic cough, weight loss, and hemoptysis.
*Symptoms that suggest non small cell lung cancer include:
*Other symptoms that suggest non small cell lung cancer include<ref name="Hamilton">{{cite journal | last =Hamilton | first =W | coauthors =  Peters TJ, Round A, Sharp D | title =What are the clinical features of lung cancer before the diagnosis is made? A population based case-control study | journal =Thorax | volume =60 | issue=12 | pages =1059–1065 | publisher = BMJ Publishing Group Ltd. | date =Dec 2005 | pmid =16227326 }}</ref><ref name="canadian">Lung cancer. Canadian Cancer Society 2015. http://www.cancer.ca/en/cancer-information/cancer-type/lung/signs-and-symptoms/?region=ab Accessed on February 24, 2015</ref>
** Chronic [[cough]]  
:* [[Dyspnea]]  
** [[Dyspnea]]  
:* [[Hemoptysis]]  
** [[Hemoptysis]]  
:* Chronic [[coughing]]
** [[Chest pain]]
:* [[Chest pain]]
** [[Abdominal pain]]
:* [[Abdominal pain]]
** [[Fatigue]]
:* [[Fatigue]]
** [[Weight loss]]
:* Loss of [[appetite]]
** [[Anorexia|Loss of appetite]]
:* [[Dysphonia]]
** [[Dysphonia]]
 
==Less Common Symptoms==
==Less Common Symptoms==
 
Other less common symptoms of non-small cell lung cancer include:<ref name="Hamilton">{{cite journal | last =Hamilton | first =W | coauthors =  Peters TJ, Round A, Sharp D | title =What are the clinical features of lung cancer before the diagnosis is made? A population based case-control study | journal =Thorax | volume =60 | issue=12 | pages =1059–1065 | publisher = BMJ Publishing Group Ltd. | date =Dec 2005 | pmid =16227326 }}</ref><ref name="canadian">Lung cancer. Canadian Cancer Society 2015. http://www.cancer.ca/en/cancer-information/cancer-type/lung/signs-and-symptoms/?region=ab Accessed on February 24, 2015</ref>
*Other less common symptoms of non-small cell lung cancer include:  
* Symptoms during later stage of non-small cell lung cancer include:
'''Late Symptoms'''
** [[Bone pain]]
:* [[Bone pain]]
** [[Dysphagia]]
:* [[Dysphagia]]
** [[Fatigue]]
:* [[Fatigue]]
** [[Paresthesia|Numbness in extremities]]
:* Numbness in extremities
** [[Dizziness]]
:* [[Dizziness]]
** [[Seizure]]
:* [[Seizure]]
 


==References==
==References==

Latest revision as of 15:57, 9 January 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2]

Overview

The hallmark of non-small cell lung cancer is chronic cough, weight loss, and hemoptysis. A positive history of smoking, exposure to asbestos, tuberculosis infection, or a high risk occupation may be suggestive of non-small cell lung cancer. Symptoms related with non-small cell lung cancer will vary depending on the size and location of the tumor. Common symptoms of non-small cell lung cancer may also include shortness of breath, fatigue, and chest pain.

History

Obtaining the history is an important aspect of making a diagnosis of non-small cell lung cancer.

  • Past medical, social and family history provides important insight into natural evolution of the disease.
  • Complete history will help determine the likelihood of metastases and the association with other conditions.
  • Specific areas of focus when obtaining the history, are outlined below:[1][2]

Common Symptoms

The majority of non-small cell lung cancers are asymptomatic and are usually found incidentally. The hallmark of non-small cell lung cancer is chronic cough, weight loss, and hemoptysis.[3][4]

Less Common Symptoms

Other less common symptoms of non-small cell lung cancer include:[3][4]

References

  1. Kaerlev L, Teglbjaerg PS, Sabroe S, Kolstad HA, Ahrens W, Eriksson M, Guénel P, Gorini G, Hardell L, Cyr D, Zambon P, Stang A, Olsen J (2002). "The importance of smoking and medical history for development of small bowel carcinoid tumor: a European population-based case-control study". Cancer Causes Control. 13 (1): 27–34. PMID 11899115.
  2. Raz DJ, Zell JA, Ou SH, Gandara DR, Anton-Culver H, Jablons DM (2007). "Natural history of stage I non-small cell lung cancer: implications for early detection". Chest. 132 (1): 193–9. doi:10.1378/chest.06-3096. PMID 17505036.
  3. 3.0 3.1 Hamilton, W (Dec 2005). "What are the clinical features of lung cancer before the diagnosis is made? A population based case-control study". Thorax. BMJ Publishing Group Ltd. 60 (12): 1059–1065. PMID 16227326. Unknown parameter |coauthors= ignored (help)
  4. 4.0 4.1 Lung cancer. Canadian Cancer Society 2015. http://www.cancer.ca/en/cancer-information/cancer-type/lung/signs-and-symptoms/?region=ab Accessed on February 24, 2015


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