Nephrotic syndrome causes

	Nephrotic Syndrome Microchapters
Home
Patient Information
Overview
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating Nephrotic syndrome from other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications and Prognosis
Diagnosis
Diagnostic Study of choice
History and Symptoms
Physical Examination
Laboratory Findings
Electrocardiogram
Chest X-Ray
Echocardiography or Ultrasound
CT Scan
MRI
Other Imaging Findings
Other Diagnostic Studies
Treatment
Medical Therapy
Surgery
Primary Prevention
Secondary Prevention
Cost-Effectiveness of Therapy
Future or Investigational Therapies
Case Studies
Case #1
Nephrotic syndrome causes On the Web
Most recent articles
Most cited articles
Review articles
CME Programs
Powerpoint slides
Images
American Roentgen Ray Society Images of Nephrotic syndrome causes All Images X-rays Echo & Ultrasound CT Images MRI
Ongoing Trials at Clinical Trials.gov
US National Guidelines Clearinghouse
NICE Guidance
FDA on Nephrotic syndrome causes
CDC on Nephrotic syndrome causes
Nephrotic syndrome causes in the news
Blogs on Nephrotic syndrome causes
Directions to Hospitals Treating Nephrotic syndrome
Risk calculators and risk factors for Nephrotic syndrome causes

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Causes

Primary Causes

Primary renal disorders, such as primary glomerulonephritides, may cause primary nephrotic syndrome. Differentiation between different types of glomerular diseases is often made by clinical suspicion and by renal biopsy, which includes light microscopy, immunofluorescence, and ideally electron microscopy.

Secondary Causes

Secondary causes of renal disorders cause secondary nephrotic syndrome. The most common cause of secondary nephrotic syndrome in adults is diabetes mellitus.

The following conditions must always be considered in the differential diagnosis of nephrotic syndrome.

**Common Causes of Nephrotic Syndrome by Age**
Age (Years)	Cause of Nephrotic Syndrome
< 15	Congenital nephrotic syndrome Minimal change disease Focal segmental glomerulosclerosis Membranous nephropathy
15-40	Focal segmental glomerulosclerosis Lupus nephritis Minimal change disease Membranous nephropathy Diabetic nephropathy Pre-eclampsia Late post-infectious glomerulonephritis IgA nephropathy
> 40	Focal segmental glomerulosclerosis Membranous nephropathy Diabetic nephropathy Minimal change disease IgA nephropathy Primary amyloidosis Light chain deposition disease Benign nephrosclerosis Late post-infectious glomerulonephritis

^{Adapted from Rose BD. Pathophysiology of renal diseases, ed. 2. New York, McGraw-Hill, 1987,p. 167}

List of Secondary Causes of Nephrotic Syndrome^[1]

Drug Induced

Sodium aurothiomalate

References

↑ Eddy AA, Symons JM (2003). "Nephrotic syndrome in childhood". Lancet. 362 (9384): 629–39. doi:10.1016/S0140-6736(03)14184-0. PMID 12944064.

Template:WH Template:WS

[pmid12944064-1] Eddy AA, Symons JM (2003). "Nephrotic syndrome in childhood". Lancet. 362 (9384): 629–39. doi:10.1016/S0140-6736(03)14184-0. PMID 12944064.

[1]