Multiple endocrine neoplasia type 1 historical perspective: Difference between revisions
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{{Multiple endocrine neoplasia type 1}} | {{Multiple endocrine neoplasia type 1}} | ||
{{CMG}}; {{AE}} {{Ammu}} | {{CMG}}; {{AE}} {{Ammu}} | ||
==Overview== | ==Overview== | ||
Multiple endocrine neoplasia type 1 was first described by Dr. Erdheim, a German physician, in 1903 by reporting a case of an [[acromegaly|acromegalic]] patient with [[pituitary adenoma]] and three enlarged [[parathyroid gland]]s. | Multiple endocrine neoplasia type 1 was first described by Dr.Erdheim, a German physician, in 1903 by reporting a case of an [[acromegaly|acromegalic]] patient with [[pituitary adenoma]] and three enlarged [[parathyroid gland]]s. | ||
==Historical Perspective== | ==Historical Perspective== | ||
<br> | The following table describes the major historically significant events about multiple endocrine neoplasia type 1.<br> | ||
{| style="border: 0px; font-size: 90%; margin: 3px;" align=center | {| style="border: 0px; font-size: 90%; margin: 3px;" align="center" | ||
|+''''' | |+'''''MEN I Historical Background''''' | ||
! style="background: #4479BA; width: 120px;" | {{fontcolor|#FFF|Years}} | ! style="background: #4479BA; width: 120px;" | {{fontcolor|#FFF|Years}} | ||
! style="background: #4479BA; width: 550px;" | {{fontcolor|#FFF|Scientist}} | ! style="background: #4479BA; width: 550px;" | {{fontcolor|#FFF|Scientist}} | ||
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! style="background: #DCDCDC;" |1903 | ! style="background: #DCDCDC;" |1903 | ||
! style="background: #F5F5F5;" |Erdheim | ! style="background: #F5F5F5;" |Erdheim | ||
| style="padding: 5px 5px; background: #F5F5F5;" |Reported case of an [[acromegaly|acromegalic]] patient with [[pituitary adenoma]] and three enlarged [[parathyroid gland]]s. | |||
|- | |- | ||
! style="background: #DCDCDC;" |1953 | ! style="background: #DCDCDC;" |1953 | ||
! style="background: #F5F5F5;" |Underdahl | ! style="background: #F5F5F5;" |Underdahl | ||
| style="padding: 5px 5px; background: #F5F5F5;" |Reported case series of patients with syndrome of [[pituitary]], [[parathyroid]], and pancreatic islet adenomas. | |||
|- | |- | ||
! style="background: #DCDCDC;" |1954 | ! style="background: #DCDCDC;" |1954 | ||
! style="background: #F5F5F5;" |Wermer | ! style="background: #F5F5F5;" |Wermer | ||
| style="padding: 5px 5px; background: #F5F5F5;" |Identified that multiple endocrine neoplasia was transmitted as a [[dominant]] trait. | |||
|- | |- | ||
! style="background: #DCDCDC;" |1962 | ! style="background: #DCDCDC;" |1962 | ||
! style="background: #F5F5F5;" |Williams and Celestin | ! style="background: #F5F5F5;" |Williams and Celestin | ||
| style="padding: 5px 5px; background: #F5F5F5;" |First described bronchial [[carcinoid]] as a feature of multiple endocrine neoplasia type 1. | |||
|- | |- | ||
! style="background: #DCDCDC;" |1963 | ! style="background: #DCDCDC;" |1963 | ||
! style="background: #F5F5F5;" |Jacobs and Underwood | ! style="background: #F5F5F5;" |Jacobs and Underwood | ||
| style="padding: 5px 5px; background: #F5F5F5;" |Reported case of [[hypoglycemia]] and [[islet cell]] [[adenoma]]s in 3 members of the family, with father having [[hyperparathyroidism]] and [[lung cancer|broncial carcinoma]] and son and daughter with idiopathic [[epilepsy]] <ref name="pmid14056823">{{cite journal| author=UNDERWOOD LE, JACOBS NM| title=FAMILIAL ENDOCRINE ADENOMATOSIS. A FAMILY WITH HYPERINSULINISM AS THE PREDOMINANT MANIFESTATION. | journal=Am J Dis Child | year= 1963 | volume= 106 | issue= | pages= 218-23 | pmid=14056823 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=14056823 }} </ref>. | |||
|- | |- | ||
! style="background: #DCDCDC;" |1966 | ! style="background: #DCDCDC;" |1966 | ||
! style="background: #F5F5F5;" |Guida | ! style="background: #F5F5F5;" |Guida | ||
| style="padding: 5px 5px; background: #F5F5F5;" |Identified [[pituitary adenoma]] and duodenal [[carcinoid]] in patients with multiple endocrine neoplasia type 1 syndrome <ref name="pmid4288594">{{cite journal| author=Guida PM, Todd JE, Mooe SW, Beal JM| title=Zollinger-Ellison syndrome with interesting variations. Report of twelve cases including one of carcinoid of the duodenum. | journal=Am J Surg | year= 1966 | volume= 112 | issue= 6 | pages= 807-17 | pmid=4288594 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=4288594 }} </ref>. | |||
|- | |- | ||
! style="background: #DCDCDC;" |1967 | ! style="background: #DCDCDC;" |1967 | ||
! style="background: #F5F5F5;" |Johnson | ! style="background: #F5F5F5;" |Johnson | ||
| style="padding: 5px 5px; background: #F5F5F5;" |Presented a multiple endocrine neoplasia type 1 case devoid of [[peptic ulcer]] <ref name="pmid4384073">{{cite journal| author=Johnson GJ, Summerskill WH, Anderson VE, Keating FR| title=Clinical and genetic investigation of a large kindred with multiple endocrine adenomatosis. | journal=N Engl J Med | year= 1967 | volume= 277 | issue= 26 | pages= 1379-85 | pmid=4384073 | doi=10.1056/NEJM196712282772601 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=4384073 }} </ref>. | |||
|- | |- | ||
! style="background: #DCDCDC;" |1968 | ! style="background: #DCDCDC;" |1968 | ||
! style="background: #F5F5F5;" |Steiner | ! style="background: #F5F5F5;" |Steiner | ||
| style="padding: 5px 5px; background: #F5F5F5;" |Introduced the term "multiple endocrine neoplasia" (MEN) to describe disorders featuring combinations of [[endocrine]] [[tumor]]s and proposed the terms 'Wermer syndrome' for multiple endocrine neoplasia type 1 and 'Sipple syndrome' for multiple endocrine neoplasia type 2. | |||
|- | |- | ||
! style="background: #DCDCDC;" |1972 | ! style="background: #DCDCDC;" |1972 | ||
! style="background: #F5F5F5;" | Vance | ! style="background: #F5F5F5;" | Vance | ||
| style="padding: 5px 5px; background: #F5F5F5;" |Suggested the importance of primary genetic [[lesion]] in endocrine [[adenomatosis]] in developing [[neoplasia]] and hyperfunctioning of islet of langerhans <ref>[http://omim.org/entry/131100] MULTIPLE ENDOCRINE NEOPLASIA, TYPE I; MEN1</ref>. | |||
|- | |- | ||
! style="background: #DCDCDC;" |1982 | ! style="background: #DCDCDC;" |1982 | ||
! style="background: #F5F5F5;" |McCarthy | ! style="background: #F5F5F5;" |McCarthy | ||
| style="padding: 5px 5px; background: #F5F5F5;" |Identified 2 different causes of [[Zollinger-Ellison syndrome]], [[malignant]] type and the one linked with multiple endocrine neoplasia type 1 <ref name="pmid7044271">{{cite journal| author=McCarthy DM| title=Zollinger-Ellison syndrome. | journal=Annu Rev Med | year= 1982 | volume= 33 | issue= | pages= 197-215 | pmid=7044271 | doi=10.1146/annurev.me.33.020182.001213 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=7044271 }} </ref>. | |||
|- | |- | ||
! style="background: #DCDCDC;" |1983 | ! style="background: #DCDCDC;" |1983 | ||
! style="background: #F5F5F5;" |Hershon | ! style="background: #F5F5F5;" |Hershon | ||
| style="padding: 5px 5px; background: #F5F5F5;" |Identified family members from Pacific Northwest with [[prolactinoma]]s but with no [[pancreatic tumor]]s. | |||
|- | |- | ||
! style="background: #DCDCDC;" |1985 | ! style="background: #DCDCDC;" |1985 | ||
! style="background: #F5F5F5;" |Bear | ! style="background: #F5F5F5;" |Bear | ||
| style="padding: 5px 5px; background: #F5F5F5;" |Referred the disorders reported from Burin as multiple endocrine neoplasia type 1 Burin. | |||
|- | |||
! style="background: #DCDCDC;" |1986 | |||
! style="background: #F5F5F5;" |Brandi | |||
| style="padding: 5px 5px; background: #F5F5F5;" |Suggested the [[humoral]] cause of primary [[hyperparathyroidism]] in familial multiple endocrine neoplasia type 1. | |||
|- | |||
! style="background: #DCDCDC;" |1986 | |||
! style="background: #F5F5F5;" |Schimke | |||
| style="padding: 5px 5px; background: #F5F5F5;" |Suggested a 2 step model of [[pathogenesis]] which include [[germline mutation]] followed by somatic [[mutation]] later. | |||
|- | |||
! style="background: #DCDCDC;" |1986 | |||
! style="background: #F5F5F5;" |Bahn | |||
| style="padding: 5px 5px; background: #F5F5F5;" |Identified 25 year old monozygotic twins with one having primary [[hyperparathyroidism]], [[Zollinger-Ellison syndrome]], [[cushing's disease]], and [[hyperprolactinemia]] and the other have primary [[hyperparathyroidism]] and [[hyperprolactinemia]] <ref name="pmid2875227">{{cite journal| author=Bahn RS, Scheithauer BW, van Heerden JA, Laws ER, Horvath E, Gharib H| title=Nonidentical expressions of multiple endocrine neoplasia, type I, in identical twins. | journal=Mayo Clin Proc | year= 1986 | volume= 61 | issue= 9 | pages= 689-96 | pmid=2875227 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=2875227 }} </ref>. | |||
|- | |- | ||
! style="background: #DCDCDC;" |1986 | ! style="background: #DCDCDC;" |1986 | ||
! style="background: #F5F5F5;" | | ! style="background: #F5F5F5;" |Maton | ||
| style="padding: 5px 5px; background: #F5F5F5;" |Identified that [[cushing's syndrome]] is more common with [[Zollinger-Ellison syndrome]] <ref name="pmid2872593">{{cite journal| author=Maton PN, Gardner JD, Jensen RT| title=Cushing's syndrome in patients with the Zollinger-Ellison syndrome. | journal=N Engl J Med | year= 1986 | volume= 315 | issue= 1 | pages= 1-5 | pmid=2872593 | doi=10.1056/NEJM198607033150101 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=2872593 }} </ref>. | |||
|- | |- | ||
! style="background: #DCDCDC;" |1988 | ! style="background: #DCDCDC;" |1988 | ||
! style="background: #F5F5F5;" | | ! style="background: #F5F5F5;" | | ||
| style="padding: 5px 5px; background: #F5F5F5;" |The multiple endocrine neoplasia type 1 [[locus]] was assigned to [[chromosome]] 11 (11q13). | |||
|- | |- | ||
! style="background: #DCDCDC;" |1993 | ! style="background: #DCDCDC;" |1993 | ||
! style="background: #F5F5F5;" |Gaitan | ! style="background: #F5F5F5;" |Gaitan | ||
| style="padding: 5px 5px; background: #F5F5F5;" |Described mother and daughter with [[cushing's disease]] due to [[ACTH]] secreting [[tumor]] <ref name="pmid8099078">{{cite journal| author=Gaitan D, Loosen PT, Orth DN| title=Two patients with Cushing's disease in a kindred with multiple endocrine neoplasia type I. | journal=J Clin Endocrinol Metab | year= 1993 | volume= 76 | issue= 6 | pages= 1580-2 | pmid=8099078 | doi=10.1210/jcem.76.6.8099078 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8099078 }} </ref>. | |||
|- | |- | ||
! style="background: #DCDCDC;" |1994 | ! style="background: #DCDCDC;" |1994 | ||
! style="background: #F5F5F5;" |Petty | ! style="background: #F5F5F5;" |Petty | ||
| style="padding: 5px 5px; background: #F5F5F5;" |Identified that [[gene]] involved in Pacific Northwest studies and Burin studies linked to 11q [[chromosome]]. | |||
|- | |- | ||
! style="background: #DCDCDC;" |1997 | ! style="background: #DCDCDC;" |1997 | ||
! style="background: #F5F5F5;" |Darling | ! style="background: #F5F5F5;" |Darling | ||
| style="padding: 5px 5px; background: #F5F5F5;" |Suggested that one of the diagnostic findings of multiple endocrine neoplasia type 1 is cutaneous manifestations. | |||
|- | |- | ||
! style="background: #DCDCDC;" |1998 | ! style="background: #DCDCDC;" |1998 | ||
! style="background: #F5F5F5;" | | ! style="background: #F5F5F5;" | | ||
| style="padding: 5px 5px; background: #F5F5F5;" |The multiple endocrine neoplasia type 1 [[gene]] was [[cloned]] <ref name="Guru1998">Guru SC, Manickam P, Crabtree JS, Olufemi SE, Agarwal SK, Debelenko LV. Identification and characterization of the multiple endocrine neoplasia type 1 (MEN1) gene. ''J Intern Med'' 243(6) 433-9</ref>. | |||
|- | |- | ||
! style="background: #DCDCDC;" |1999 | ! style="background: #DCDCDC;" |1999 | ||
! style="background: #F5F5F5;" |Yu | ! style="background: #F5F5F5;" |Yu | ||
| style="padding: 5px 5px; background: #F5F5F5;" |Identified that gastrinoma growth is the single most important factor in deciding the long term survival of patients with [[Zollinger-Ellison syndrome]] <ref name="pmid10080607">{{cite journal| author=Yu F, Venzon DJ, Serrano J, Goebel SU, Doppman JL, Gibril F et al.| title=Prospective study of the clinical course, prognostic factors, causes of death, and survival in patients with long-standing Zollinger-Ellison syndrome. | journal=J Clin Oncol | year= 1999 | volume= 17 | issue= 2 | pages= 615-30 | pmid=10080607 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10080607 }} </ref>. | |||
|- | |||
|- | |- | ||
! style="background: #DCDCDC;" |2001 | ! style="background: #DCDCDC;" |2001 | ||
! style="background: #F5F5F5;" |Bordi | ! style="background: #F5F5F5;" |Bordi | ||
| style="padding: 5px 5px; background: #F5F5F5;" |Identified patients with multiple endocrine neoplasia syndrome to have carcinoid tumors <ref name="pmid11344233">{{cite journal| author=Bordi C, Corleto VD, Azzoni C, Pizzi S, Ferraro G, Gibril F et al.| title=The antral mucosa as a new site for endocrine tumors in multiple endocrine neoplasia type 1 and Zollinger-Ellison syndromes. | journal=J Clin Endocrinol Metab | year= 2001 | volume= 86 | issue= 5 | pages= 2236-42 | pmid=11344233 | doi=10.1210/jcem.86.5.7479 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11344233 }} </ref>. | |||
|} | |} | ||
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[[Category:Endocrinology]] | |||
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[[Category:Oncology]] | |||
[[Category:Medicine]] | |||
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Latest revision as of 02:45, 27 November 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [2]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [3]
Overview
Multiple endocrine neoplasia type 1 was first described by Dr.Erdheim, a German physician, in 1903 by reporting a case of an acromegalic patient with pituitary adenoma and three enlarged parathyroid glands.
Historical Perspective
The following table describes the major historically significant events about multiple endocrine neoplasia type 1.
Years | Scientist | Contribution |
---|---|---|
1903 | Erdheim | Reported case of an acromegalic patient with pituitary adenoma and three enlarged parathyroid glands. |
1953 | Underdahl | Reported case series of patients with syndrome of pituitary, parathyroid, and pancreatic islet adenomas. |
1954 | Wermer | Identified that multiple endocrine neoplasia was transmitted as a dominant trait. |
1962 | Williams and Celestin | First described bronchial carcinoid as a feature of multiple endocrine neoplasia type 1. |
1963 | Jacobs and Underwood | Reported case of hypoglycemia and islet cell adenomas in 3 members of the family, with father having hyperparathyroidism and broncial carcinoma and son and daughter with idiopathic epilepsy [1]. |
1966 | Guida | Identified pituitary adenoma and duodenal carcinoid in patients with multiple endocrine neoplasia type 1 syndrome [2]. |
1967 | Johnson | Presented a multiple endocrine neoplasia type 1 case devoid of peptic ulcer [3]. |
1968 | Steiner | Introduced the term "multiple endocrine neoplasia" (MEN) to describe disorders featuring combinations of endocrine tumors and proposed the terms 'Wermer syndrome' for multiple endocrine neoplasia type 1 and 'Sipple syndrome' for multiple endocrine neoplasia type 2. |
1972 | Vance | Suggested the importance of primary genetic lesion in endocrine adenomatosis in developing neoplasia and hyperfunctioning of islet of langerhans [4]. |
1982 | McCarthy | Identified 2 different causes of Zollinger-Ellison syndrome, malignant type and the one linked with multiple endocrine neoplasia type 1 [5]. |
1983 | Hershon | Identified family members from Pacific Northwest with prolactinomas but with no pancreatic tumors. |
1985 | Bear | Referred the disorders reported from Burin as multiple endocrine neoplasia type 1 Burin. |
1986 | Brandi | Suggested the humoral cause of primary hyperparathyroidism in familial multiple endocrine neoplasia type 1. |
1986 | Schimke | Suggested a 2 step model of pathogenesis which include germline mutation followed by somatic mutation later. |
1986 | Bahn | Identified 25 year old monozygotic twins with one having primary hyperparathyroidism, Zollinger-Ellison syndrome, cushing's disease, and hyperprolactinemia and the other have primary hyperparathyroidism and hyperprolactinemia [6]. |
1986 | Maton | Identified that cushing's syndrome is more common with Zollinger-Ellison syndrome [7]. |
1988 | The multiple endocrine neoplasia type 1 locus was assigned to chromosome 11 (11q13). | |
1993 | Gaitan | Described mother and daughter with cushing's disease due to ACTH secreting tumor [8]. |
1994 | Petty | Identified that gene involved in Pacific Northwest studies and Burin studies linked to 11q chromosome. |
1997 | Darling | Suggested that one of the diagnostic findings of multiple endocrine neoplasia type 1 is cutaneous manifestations. |
1998 | The multiple endocrine neoplasia type 1 gene was cloned [9]. | |
1999 | Yu | Identified that gastrinoma growth is the single most important factor in deciding the long term survival of patients with Zollinger-Ellison syndrome [10]. |
2001 | Bordi | Identified patients with multiple endocrine neoplasia syndrome to have carcinoid tumors [11]. |
References
- ↑ UNDERWOOD LE, JACOBS NM (1963). "FAMILIAL ENDOCRINE ADENOMATOSIS. A FAMILY WITH HYPERINSULINISM AS THE PREDOMINANT MANIFESTATION". Am J Dis Child. 106: 218–23. PMID 14056823.
- ↑ Guida PM, Todd JE, Mooe SW, Beal JM (1966). "Zollinger-Ellison syndrome with interesting variations. Report of twelve cases including one of carcinoid of the duodenum". Am J Surg. 112 (6): 807–17. PMID 4288594.
- ↑ Johnson GJ, Summerskill WH, Anderson VE, Keating FR (1967). "Clinical and genetic investigation of a large kindred with multiple endocrine adenomatosis". N Engl J Med. 277 (26): 1379–85. doi:10.1056/NEJM196712282772601. PMID 4384073.
- ↑ [1] MULTIPLE ENDOCRINE NEOPLASIA, TYPE I; MEN1
- ↑ McCarthy DM (1982). "Zollinger-Ellison syndrome". Annu Rev Med. 33: 197–215. doi:10.1146/annurev.me.33.020182.001213. PMID 7044271.
- ↑ Bahn RS, Scheithauer BW, van Heerden JA, Laws ER, Horvath E, Gharib H (1986). "Nonidentical expressions of multiple endocrine neoplasia, type I, in identical twins". Mayo Clin Proc. 61 (9): 689–96. PMID 2875227.
- ↑ Maton PN, Gardner JD, Jensen RT (1986). "Cushing's syndrome in patients with the Zollinger-Ellison syndrome". N Engl J Med. 315 (1): 1–5. doi:10.1056/NEJM198607033150101. PMID 2872593.
- ↑ Gaitan D, Loosen PT, Orth DN (1993). "Two patients with Cushing's disease in a kindred with multiple endocrine neoplasia type I." J Clin Endocrinol Metab. 76 (6): 1580–2. doi:10.1210/jcem.76.6.8099078. PMID 8099078.
- ↑ Guru SC, Manickam P, Crabtree JS, Olufemi SE, Agarwal SK, Debelenko LV. Identification and characterization of the multiple endocrine neoplasia type 1 (MEN1) gene. J Intern Med 243(6) 433-9
- ↑ Yu F, Venzon DJ, Serrano J, Goebel SU, Doppman JL, Gibril F; et al. (1999). "Prospective study of the clinical course, prognostic factors, causes of death, and survival in patients with long-standing Zollinger-Ellison syndrome". J Clin Oncol. 17 (2): 615–30. PMID 10080607.
- ↑ Bordi C, Corleto VD, Azzoni C, Pizzi S, Ferraro G, Gibril F; et al. (2001). "The antral mucosa as a new site for endocrine tumors in multiple endocrine neoplasia type 1 and Zollinger-Ellison syndromes". J Clin Endocrinol Metab. 86 (5): 2236–42. doi:10.1210/jcem.86.5.7479. PMID 11344233.