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WikiDoc Resources for Neoplasia


Most recent articles on Neoplasia

Most cited articles on Neoplasia

Review articles on Neoplasia

Articles on Neoplasia in N Eng J Med, Lancet, BMJ


Powerpoint slides on Neoplasia

Images of Neoplasia

Photos of Neoplasia

Podcasts & MP3s on Neoplasia

Videos on Neoplasia

Evidence Based Medicine

Cochrane Collaboration on Neoplasia

Bandolier on Neoplasia

TRIP on Neoplasia

Clinical Trials

Ongoing Trials on Neoplasia at Clinical

Trial results on Neoplasia

Clinical Trials on Neoplasia at Google

Guidelines / Policies / Govt

US National Guidelines Clearinghouse on Neoplasia

NICE Guidance on Neoplasia


FDA on Neoplasia

CDC on Neoplasia


Books on Neoplasia


Neoplasia in the news

Be alerted to news on Neoplasia

News trends on Neoplasia


Blogs on Neoplasia


Definitions of Neoplasia

Patient Resources / Community

Patient resources on Neoplasia

Discussion groups on Neoplasia

Patient Handouts on Neoplasia

Directions to Hospitals Treating Neoplasia

Risk calculators and risk factors for Neoplasia

Healthcare Provider Resources

Symptoms of Neoplasia

Causes & Risk Factors for Neoplasia

Diagnostic studies for Neoplasia

Treatment of Neoplasia

Continuing Medical Education (CME)

CME Programs on Neoplasia


Neoplasia en Espanol

Neoplasia en Francais


Neoplasia in the Marketplace

Patents on Neoplasia

Experimental / Informatics

List of terms related to Neoplasia

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]


Neoplasia (new growth in Greek) is abnormal and purposeless proliferation of cells in a tissue or organ. A neoplastic growth is called a neoplasm. Most neoplasms proliferate to form distinct masses, or tumors, but there are also many examples of neoplastic processes which are not grossly apparent, a commonly diagnosed example being cervical intraepithelial neoplasia, a pre-cancerous lesion of the uterine cervix. It is important to note that the term "neoplasm" is not synonymous with cancer, since neoplasms can be either benign or malignant. Leiomyoma (fibroids of the uterus) and melanocytic nevi (moles) are the most common types of neoplasms - both are benign. On the other hand, cancer is a typical example of malignant neoplasia or tumor. Hence, it is important to be able to differentiate between neoplasia, tumor and cancer.

Interestingly, there is not a complete consensus in the biomedical community as to the exact biological definition of a neoplasm, although the statement of the British oncologist R.A. Willis is widely cited:

A neoplasm is an abnormal mass of tissue, the growth of which exceeds and is uncoordinated with that of the normal tissues, and persists in the same excessive manner after cessation of the stimulus which evoked the change.[1]

Neoplastic tumors often contain more than one type of cell, but their initiation and continued growth is usually dependent on a single population of neoplastic cells. These cells are clonal - that is, they are descended from a single progenitor cell. The neoplastic cells typically bear common genetic or epigenetic abnormalities which are not seen in the non-neoplastic stromal cells and blood-vessel forming cells, whose growth is dependent on molecular stimuli from the neoplastic cells. The demonstration of clonality is now considered by many to be necessary (though not sufficient) to define a cellular proliferation as neoplastic.

Other uses

Neoplasia is also the name of a scientific journal for oncology research or a name of a Computer Demo Group, formed in 1995 (NPL). There is also a movie (Link), inspired by the releases of the demogroup.

See also

External links


  1. Willis RA: The Spread of Tumors in the Human Body. London, Butterworth & Co, 1952

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