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==Historical Perspective==
==Historical Perspective==
 
The first case of mucormycosis in humans was reported in 1885 by a German pathologist named Paltauf, who published a case of upper airway mucormycosis, entitled: “mucormycosis mucorina” in the Virchows archives of pathology and anatomy<ref name="pmid11871522">{{cite journal |vauthors=Bell S, Mahoney L |title=Mucormycosis: a case study |journal=Crit Care Nurse |volume=20 |issue=1 |pages=18–23 |year=2000 |pmid=11871522 |doi= |url=}}</ref> Gregory et al described the first case of of rhino-orbital cerebral mucormycosis in 1943 associated with diabetes. Harris in 1955 reported the first known survivor. Mucormycosis is certainly seen less than other common fungal infections like candidiasis or aspergillosis. However, its incidence has been increasing recently. Brown has reported that the frequency of zygomycosis has been increasing over the past 14 years in the United States of America; this fungal infection has been identified in up to 6.8% of patients at autopsy.<ref name="pmid16333056">{{cite journal |vauthors=Brown J |title=Zygomycosis: an emerging fungal infection |journal=Am J Health Syst Pharm |volume=62 |issue=24 |pages=2593–6 |year=2005 |pmid=16333056 |doi=10.2146/ajhp050188 |url=}}</ref> Another study confirmed that the incidence of this infection is also on the rise in Europe.<ref name="pmid19391253">{{cite journal |vauthors=Lass-Flörl C |title=The changing face of epidemiology of invasive fungal disease in Europe |journal=Mycoses |volume=52 |issue=3 |pages=197–205 |year=2009 |pmid=19391253 |doi= |url=}}</ref> This rise is partially explained by better diagnostic tools, increased incidence of diabetes mellitus and use of immunosuppressive agents in the modern therapeutic era.<ref name="pmid19568978">{{cite journal |vauthors=Saegeman V, Maertens J, Ectors N, Meersseman W, Lagrou K |title=Epidemiology of mucormycosis: review of 18 cases in a tertiary care hospital |journal=Med. Mycol. |volume=48 |issue=2 |pages=245–54 |year=2010 |pmid=19568978 |doi=10.1080/13693780903059477 |url=}}</ref>
==References==
==References==
{{Reflist|2}}
{{Reflist|2}}

Revision as of 16:43, 7 June 2017

Mucormycosis Microchapters

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Overview

Historical Perspective

Classification

Pathophysiology

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Differentiating Mucormycosis from other Diseases

Epidemiology and Demographics

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Diagnosis

Diagnostic Criteria

History and Symptoms

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Treatment

Medical Therapy

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Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

Historical Perspective

The first case of mucormycosis in humans was reported in 1885 by a German pathologist named Paltauf, who published a case of upper airway mucormycosis, entitled: “mucormycosis mucorina” in the Virchows archives of pathology and anatomy[1] Gregory et al described the first case of of rhino-orbital cerebral mucormycosis in 1943 associated with diabetes. Harris in 1955 reported the first known survivor. Mucormycosis is certainly seen less than other common fungal infections like candidiasis or aspergillosis. However, its incidence has been increasing recently. Brown has reported that the frequency of zygomycosis has been increasing over the past 14 years in the United States of America; this fungal infection has been identified in up to 6.8% of patients at autopsy.[2] Another study confirmed that the incidence of this infection is also on the rise in Europe.[3] This rise is partially explained by better diagnostic tools, increased incidence of diabetes mellitus and use of immunosuppressive agents in the modern therapeutic era.[4]

References

  1. Bell S, Mahoney L (2000). "Mucormycosis: a case study". Crit Care Nurse. 20 (1): 18–23. PMID 11871522.
  2. Brown J (2005). "Zygomycosis: an emerging fungal infection". Am J Health Syst Pharm. 62 (24): 2593–6. doi:10.2146/ajhp050188. PMID 16333056.
  3. Lass-Flörl C (2009). "The changing face of epidemiology of invasive fungal disease in Europe". Mycoses. 52 (3): 197–205. PMID 19391253.
  4. Saegeman V, Maertens J, Ectors N, Meersseman W, Lagrou K (2010). "Epidemiology of mucormycosis: review of 18 cases in a tertiary care hospital". Med. Mycol. 48 (2): 245–54. doi:10.1080/13693780903059477. PMID 19568978.

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