Hypotension resident survival guide

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ogheneochuko Ajari, MB.BS, MS [2], Javaria Anwer M.D.[3]
Synonyms and keywords: Low blood pressure resident survival guide, Low blood pressure management guide, guide to hypotension management, hypotension management guide, hypotension management algorithm

Lymphadenopathy resident survival guide microchapters
Overview
Causes
Diagnosis and Management
Do's
Don'ts

Overview

Hypotension means low blood pressure (BP). A systoloc BP measuring less than 90mmHg and/ or diastolic BP of less than 60mmHg is considered hypotension.

Causes

Life Threatening Causes

Life-threatening causes include conditions that result in death or permanent disability within 24 hours if left untreated.

Common Causes

The algorithm illustrates common causes of hypotension based upon the etiology.[1][2][3][4]

 
 
 
 
 
 
 
 
Causes of hypotension
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Vasodilation
 
Neurogenic
Vasovagal syncope/
Neurocardiogenic syncope
❑ Post-parandial hypotension
 
Cardiogenic
 
Orthostatic hypotension
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Neurogenic
 
 
 
 
Iatrogenic
 
 
 
 
Non-neurgenic
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Medications
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Peripheral autonomic

Diabetic autonomic neuropathy
❑ Acquired non-diabetic autonomic neuropathy

Hereditary autonomic neuropathy
 
Neurodegenerative

❑ Pure autonomic failure
Parkinson disease
❑ Diffuse lewy body disease

❑ Multiple system atrophy
 
Post-traumatic
Spinal cord injury
 
 
 
 
 
Hypovolemia

Dehydration/ low volume: Vomiting, diarrhea
Polyuria such as in diabetes mellitus
❑ Third-spacing: Burns, sepsis

Bleeding: Wounds, menorrhagia
 
Venous pooling
Prolonged bed rest
Heat stroke
 
Others

Addison's disease
❑ Aging
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 

Diagnosis and Management

Shown below is an algorithm summarizing the management of hypotension.[5][6][1][7][8][9][10]


 
 
 
 
 
 
 
Systolic BP < 90mmHg / Diastolic BP < 60mmHg OR
Difference of 20 mmHg systolic and 10 mmHg diastolic pressure
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Reassess B.P
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Diagnosis of hypotension
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Syncope/ fall/ dizziness
 
 
 
 
 
Asymptomatic
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Post-meal
History

Patient age:Usually demostrated among old individuals.
Duration of symptoms:
In chronic causes access the frequency of episodes, trigerring factors (such as specific meals), and relieving factors.
Associated symptoms:Dizziness or lightheadedness, syncope, nausea, blurred vision, cold clammy, or pale skin.
Systemic review:
Cardiovascular, respiratory, renal, hepatic, rheumatologic, and GI exam. ❑ Past medical history:Parkinsons disease, autonomic dysfunctions.
Past surgical history:

Medication history: Assess the use of medications known to cause hypotension

Family history:
 
Prolonged standing/
Stress
History

Source of history:
Patient and/ or the witnesses' description of the fall.
Patient age: Common among young individuals.
Duration of symptoms: Frequency, triggering or relieving factors.
Associated symptoms: Sinking feeling, tachycardia, sweating dizziness or lightheadedness, nausea, blurred vision, cold clammy, pale skin and blaxck out preceding syncope
Systemic review:
Cardiovascular, respiratory, renal, hepatic, rheumatologic, and GI exam. ❑ Past medical history:
Volume loss, malena,
Past surgical history:
Medication history: Assess the use of medications known to cause hypotension

Family history:A positive family history has been demonstrated in the past and indicated genetic component
 
Upon standing up
History

Source of history:
Patient or well-informed caregiver.

Patient age:
Helps determine age-specific causes,
Duration of symptoms:
(weeks in acute/severe versus years in chronic conditions).
Associated symptoms:dizziness or lightheadedness, syncope, nausea, blurred vision, cold clammy, pale skin
Systemic review:
Cardiovascular, respiratory, renal, hepatic, rheumatologic, and GI exam. ❑ Past medical history:
Volume loss, malena,
Past surgical history:Recent surgery leading to volume loss
Menstrual history: Menorrhagia
Medication history: Assess the use of medications known to cause vasodilation
Family history:

Social history:Alcohol intake may cause dehydration
 
History
Source of history:
Patient or well-informed caregiver.

Patient age:
Helps determine age-specific causes,
Duration of symptoms:
(weeks in acute/severe versus years in chronic conditions).
Associated symptoms:dizziness or lightheadedness, syncope, nausea, blurred vision, cold clammy, pale skin
Systemic review:
Cardiovascular, respiratory, renal, hepatic, rheumatologic, and GI exam. ❑ Past medical history:
Volume loss, malena,
Past surgical history:

Menstrual history: ❑ Medication history: Assess the use of medications known to cause hypotension
Family history:

Social history:

Sexual history:

Exposure:
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Tilt table test
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Tilt table test positive
 
 
 
 
 
Tilt table test negative
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Neurocardiogenic syncope
Continue with EKG and blood pressure monitoring
Beta blockers preferred initial treatment
SSRI
Fludrocortisone 0.1mg/day

Midodrine 2.5-10 TID
Scopolamine
Dual chamber pacing may be required
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Orthostatic hypotension
 
 
 
Postprandial hypotension

Advice to eat smaller, low carbohydrate meals
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Lifestyle Modification

❑ Regular blood pressure monitoring with a home monitoring kit supine and prone
❑ Maintenance of an elevated salt intake of 10g/day
❑ Maintenance of proper fluid intake to prevent dehydration

Blood sugar control
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Medical Therapy
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
History

Source of history:
Patient or well-informed caregiver.
Patient age:
Helps determine age-specific causes,
Duration of symptoms:
(weeks in acute/severe versus years in chronic conditions).
Associated symptoms:dizziness or lightheadedness, syncope, nausea, blurred vision, cold clammy, pale skin
Systemic review:
Cardiovascular, respiratory, renal, hepatic, rheumatologic, and GI exam. ❑ Past medical history:
Volume loss, malena,
Past surgical history:

Menstrual history: ❑ Medication history: Assess the use of medications known to cause hypotension
Family history:

Social history:

Sexual history:

Exposure:
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Characterise the severity of the condition
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Physical exam
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Labs and tests
 
 
 
 
 

Do's

  • Educate the patient to avoid predisposing conditions such as dehydration, alcohol, etc.
  • Discontinue or adjust dose of medication if hypotension is caused by medication side effects.
  • Advice to wear compression stockings to relieve the pain and swelling from varicose veins.

Don'ts

  • Do not over treat hypotension. Symptomatic low BP or decreased organ perfusion is a treatable entity.

References

  1. 1.0 1.1 Biswas D, Karabin B, Turner D (2019). "Role of nurses and nurse practitioners in the recognition, diagnosis, and management of neurogenic orthostatic hypotension: a narrative review". Int J Gen Med. 12: 173–184. doi:10.2147/IJGM.S170655. PMC 6501706 Check |pmc= value (help). PMID 31118743.
  2. Seger JJ (2005). "Syncope evaluation and management". Tex Heart Inst J. 32 (2): 204–6. PMC 1163473. PMID 16107115.
  3. Vanamoorthy P, Pandia MP, Bithal PK, Valiaveedan SS (January 2010). "Refractory hypotension due to intraoperative hypothermia during spinal instrumentation". Indian J Anaesth. 54 (1): 56–8. doi:10.4103/0019-5049.60500. PMC 2876912. PMID 20532075.
  4. Zhang P, Li Y, Nie K, Wang L, Zhang Y (December 2018). "Hypotension and bradycardia, a serious adverse effect of piribedil, a case report and literature review". BMC Neurol. 18 (1): 221. doi:10.1186/s12883-018-1230-1. PMC 6307137. PMID 30591018.
  5. Ricci, Fabrizio; De Caterina, Raffaele; Fedorowski, Artur (2015). "Orthostatic Hypotension". Journal of the American College of Cardiology. 66 (7): 848–860. doi:10.1016/j.jacc.2015.06.1084. ISSN 0735-1097.
  6. "Looking for Trouble: Identifying and Treating Hypotension". P T. 44 (9): 563–565. September 2019. PMC 6705478 Check |pmc= value (help). PMID 31485153.
  7. Oommen J, Chen J, Wang S, Caraccio T, Hanna A (March 2019). "Droxidopa for Hypotension of Different Etiologies: Two Case Reports". P T. 44 (3): 125–144. PMC 6385736. PMID 30828233.
  8. Newton JL, Kenny R, Lawson J, Frearson R, Donaldson P (February 2003). "Prevalence of family history in vasovagal syncope and haemodynamic response to head up tilt in first degree relatives: preliminary data for the Newcastle cohort". Clin. Auton. Res. 13 (1): 22–6. doi:10.1007/s10286-003-0077-7. PMID 12664244.
  9. Michel D (September 1983). "[Iatrogenic hypotension in the aged]". Fortschr. Med. (in German). 101 (33): 1455–8. PMID 6629270.
  10. Freeman R, Wieling W, Axelrod FB, Benditt DG, Benarroch E, Biaggioni I, Cheshire WP, Chelimsky T, Cortelli P, Gibbons CH, Goldstein DS, Hainsworth R, Hilz MJ, Jacob G, Kaufmann H, Jordan J, Lipsitz LA, Levine BD, Low PA, Mathias C, Raj SR, Robertson D, Sandroni P, Schatz I, Schondorff R, Stewart JM, van Dijk JG (April 2011). "Consensus statement on the definition of orthostatic hypotension, neurally mediated syncope and the postural tachycardia syndrome". Clin. Auton. Res. 21 (2): 69–72. doi:10.1007/s10286-011-0119-5. PMID 21431947.

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