Hypopituitarism risk factors
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [2]
Overview
Hypopituitarism has a big variety of risk factors that increase the possibility of acquiring the disease. These risk factors incluide pituitary tumor, brain injury, head trauma, genetic defects, and brain surgery.
Risk Factors
More common risk factors
Common risk factors of hypopituitarism include the following: [1]
- Pituitary tumor or space occupying lesion
- Pituitary apoplexy
- Severe loss of blood: Sheehan syndrome, or postpartum hypopituitarism
- Pituitary surgery such as hypophysectomy
- Cranial radiation
- Genetic defects
- Hypothalamic disease
- Immunosuppression such as HIV and high dose glucocorticoid intake [2][3]
- Inflammatory processes such as
- Pituitary infarction
- Infiltrative disorders such as
- Non-compliance with hormone replacemrnt therapy
Less common risk factors
Less common risk factors include:
- Infiltrative disorders such as
- Traumatic brain injury causing skull fractures
References
- ↑ Khajeh L, Blijdorp K, Neggers SJ, Ribbers GM, Dippel DW, van Kooten F (2014). "Hypopituitarism after subarachnoid haemorrhage, do we know enough?". BMC Neurol. 14: 205. doi:10.1186/s12883-014-0205-0. PMC 4207357. PMID 25312299.
- ↑ Harbeck B, Klose S, Buchfelder M, Brabant G, Lehnert H (2011). "Hypopituitarism in a HIV affected patient". Exp. Clin. Endocrinol. Diabetes. 119 (10): 633–5. doi:10.1055/s-0031-1284366. PMID 21922454.
- ↑ Morichika D, Sato-Hisamoto A, Hotta K, Takata K, Iwaki N, Uchida K, Minami D, Kubo T, Tanimoto M, Kiura K (2014). "Fatal Candida septic shock during systemic chemotherapy in lung cancer patient receiving corticosteroid replacement therapy for hypopituitarism: a case report". Jpn. J. Clin. Oncol. 44 (5): 501–5. doi:10.1093/jjco/hyu019. PMID 24646812.