Hypopituitarism (patient information): Difference between revisions

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{{Hypopituitarism (patient information)}}
'''For the WikiDoc page for this topic, click [[Hypopituitarism|here]]'''
'''For the WikiDoc page for this topic, click [[Hypopituitarism|here]]'''


{{SI}}
{{CMG}}; {{AOEIC}} {{JW}}


{{CMG}};  Jinhui Wu, MD
==Overview==
Hypopituitarism is a disorder in which the [[pituitary gland]] does not produce normal amounts of some or all of its [[hormones]]. Common causes may be [[genetic mutation]]s, head [[trauma]], [[brain tumor]], brain [[surgery]], [[radiation treatment]], [[autoimmune]] [[inflammation]], [[stroke]], [[infection]]s of the brain, [[tuberculosis]], and so on. Usual signs and symptoms include [[abdominal pain]], [[loss of appetite]], [[hypotension]], [[fatigue]] and [[weakness]], [[headache]], [[short stature]], and disorder in [[Secondary sexual characteristic|secondary sexual characters]]. Hormone tests, [[bone age]] [[X-ray]] test and cranial [[MRI]] may help [[diagnosis]]. Treatments of [[hypopituitarism]] focus on the cause of the [[disease]] and [[hormone replacement therapy]].


{{EJ}}
==What are the symptoms?==
* Signs and symptoms of [[hypopituitarism]] vary, depending on which [[Pituitary gland|pituitary]] [[Hormone|hormones]] are deficient.
** [[Abdominal pain]]
** [[Loss of appetite]] and [[weight loss]]
** [[Hypotension]]
** Sensitivity to cold
** [[Visual disturbance]]s
** [[Fatigue]] and [[weakness]]
** [[Headache]]
** Slowed growth and sexual development in children
** [[Short stature]]
** Loss of [[armpit]] or [[pubic hair]], loss of body or facial hair in men
** Cessation of [[Menstrual cycle|menstrual periods]] and [[infertility]] in women
** Decreased sexual interest in both men and women


==What is hypopituitarism?==
* Other health problems may also cause these symptoms. Only a doctor can tell for sure. A person with any of these symptoms should tell the doctor so that the problems can be diagnosed and treated as early as possible.


==How do I know if I have hypopituitarism and what are the symptoms of hypopituitarism?==
==Who is at highest risk?==
Signs and symptoms of hypopituitarism vary, depending on which pituitary hormones are deficient.
:* [[Head trauma]]


:*[[Abdominal pain]]
:*[[Loss of appetite]] and [[weight loss]]
:*[[Hypotension]]
:*Sensitivity to cold
:*[[Visual disturbance]]s
:*[[Fatigue]] and [[weakness]]
:*[[Headache]]
:*Slowed growth and sexual development in children 
:*[[Short stature]] 
:*Loss of armpit or pubic hair, loss of body or facial hair in men
:*Cessation of menstrual periods and [[infertility]] in women 
:*Decreased sexual interest in both men and women
Other health problems may also cause these symptoms. Only a doctor can tell for sure. A person with any of these symptoms should tell the doctor so that the problems can be diagnosed and treated as early as possible.
==Who is at risk for hypopituitarism?==
:*Head [[trauma]]
:*[[Brain tumor]]
:*[[Brain tumor]]
:*Brain [[surgery]]
:*Brain [[surgery]]
:*[[Radiation treatment]]
:*[[Radiation treatment]]
:*Autoimmune inflammation, such as [[hypophysitis]]
:*[[Autoimmune]] inflammation, such as [[hypophysitis]]
:*[[Stroke]]
:*[[Stroke]]
:*[[Infection]]s of the brain, such as [[meningitis]]
:*[[Infection]]s of the [[brain]], such as [[meningitis]]
:*[[Tuberculosis]]
:*[[Tuberculosis]]
:*Infiltrative diseases, such as [[sarcoidosis]], [[histiocytosis X]], [[hemochromatosis]].
:*Infiltrative diseases, such as [[sarcoidosis]], [[histiocytosis X]], and [[hemochromatosis]].
:*Severe loss of blood: [[Sheehan syndrome]], or [[postpartum hypopituitarism]]
:*Severe loss of blood: [[Sheehan syndrome]] or [[postpartum hypopituitarism]]
:*[[Genetic mutation]]s
:*[[Genetic mutation]]s


==How to know you have hypopituitarism?==
==Diagnosis==
:*Hormone tests: Patients with [[hypopituitarism]] may show low levels of [[thyroid]], [[Adrenal gland|adrenal]] or [[Sex steroid|sex hormones]]. And the doctor can determine whether these low levels are associated with inadequate [[Pituitary gland|pituitary]] hormone production.
:*[[Bone age]] x-ray test: Comparing to normal children, bone age test in patients with [[hypopituitarism]] may demonstrate a delayed physical maturation.
:*Cranial [[CT]] or [[MRI]]: Since brain diseases are the most common cause of this condition, it may show [[pituitary tumor]] signs and other characteristics in [[MRI]].


==When to seek urgent medical care?==
==Treatment options==
If you develop signs and symptoms associated with hypopituitarism, see your doctor to determine the cause. If you experience either of the following symptoms, seeking urgent medical care as soon as possible:
Treatment opinion depends on the cause and the hormaone types insufficient.  
 
:*[[Abdominal pain]]
:*[[Hypotension]]


==Treatment options==
:*Treatments of [[tumor]]: Surgical removal of tumor is the first selection for the treatment. If failed, [[radiation therapy]], or [[gamma knife]] radiation treatment may be helpful.
:*Hormone replacement therapy: This is needed to replace hormones that are no longer made by organs under the control of the pituitary gland, including [[corticosteroid]]s, [[growth hormone]], [[sex hormone]]s and [[thyroid hormone]]. [[LH]] and [[FSH]] are used in infertile women.


==Diseases with similar symptoms==
==Diseases with similar symptoms==
:*[[Congenital hypothyroidism]]
:*[[Adrenal insufficiency]]
:*[[Delayed puberty]]
:*[[Growth hormone deficiency]]
:*[[Psychogenic dwarfism]]


==Where to find medical care for hypopituitarism?==
==Where to find medical care for hypopituitarism?==
[http://maps.google.com/maps?f=q&hl=en&geocode=&q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|hypopituitarism}}}}&sll=37.0625,-95.677068&sspn=65.008093,112.148438&ie=UTF8&ll=37.0625,-95.677068&spn=91.690419,149.414063&z=2&source=embed Directions to Hospitals Treating hypopituitarism]
[http://maps.google.com/maps?q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|map+top+hospital+Hypopituitarism}}}}&oe=utf-8&rls=org.mozilla:en-US:official&client=firefox-a&um=1&ie=UTF-8&sa=N&hl=en&tab=wl Directions to Hospitals Treating Hypopituitarism]


==Prevention of hypopituitarism==
==Prevention==
At present, there is no preventable measure for [[hypopituitarism]].


==What to expect (Outook/Prognosis)?==
==What to expect (Outook/Prognosis)?==
[[Prognosis]] of [[hypopituitarism]] depends on:
:*The cause of [[hypopituitarism]]: [[Prognosis]] of [[hypopituitarism]] resulting from [[tumor]] is worse than other causes.
:*The reaction of [[hormone replacement therapy]].


==Copyleft Sources==
==Copyleft Sources==
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http://www.nlm.nih.gov/medlineplus/ency/article/000343.htm
http://www.nlm.nih.gov/medlineplus/ency/article/000343.htm
{{WH}}
{{WH}}
{{WS}}
{{WS}}
[[Category:Patient Information]]
 
 
[[Category:Medicine]]
[[Category:Endocrinology]]
[[Category:Up-To-Date]]

Latest revision as of 22:19, 29 July 2020

Hypopituitarism

Overview

What are the symptoms?

Who is at highest risk?

Diagnosis

When to seek urgent medical care?

Treatment options

Where to find medical care for Hypopituitarism?

Prevention

What to expect (Outlook/Prognosis)?

Hypopituitarism On the Web

Ongoing Trials at Clinical Trials.gov

Images of Hypopituitarism

Videos on Hypopituitarism

FDA on Hypopituitarism

CDC on Hypopituitarism

Hypopituitarismin the news

Blogs on Hypopituitarism

Directions to Hospitals Treating Hypopituitarism

Risk calculators and risk factors for Hypopituitarism

For the WikiDoc page for this topic, click here

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Jinhui Wu, M.D.

Overview

Hypopituitarism is a disorder in which the pituitary gland does not produce normal amounts of some or all of its hormones. Common causes may be genetic mutations, head trauma, brain tumor, brain surgery, radiation treatment, autoimmune inflammation, stroke, infections of the brain, tuberculosis, and so on. Usual signs and symptoms include abdominal pain, loss of appetite, hypotension, fatigue and weakness, headache, short stature, and disorder in secondary sexual characters. Hormone tests, bone age X-ray test and cranial MRI may help diagnosis. Treatments of hypopituitarism focus on the cause of the disease and hormone replacement therapy.

What are the symptoms?

  • Other health problems may also cause these symptoms. Only a doctor can tell for sure. A person with any of these symptoms should tell the doctor so that the problems can be diagnosed and treated as early as possible.

Who is at highest risk?

Diagnosis

  • Hormone tests: Patients with hypopituitarism may show low levels of thyroid, adrenal or sex hormones. And the doctor can determine whether these low levels are associated with inadequate pituitary hormone production.
  • Bone age x-ray test: Comparing to normal children, bone age test in patients with hypopituitarism may demonstrate a delayed physical maturation.
  • Cranial CT or MRI: Since brain diseases are the most common cause of this condition, it may show pituitary tumor signs and other characteristics in MRI.

Treatment options

Treatment opinion depends on the cause and the hormaone types insufficient.

Diseases with similar symptoms

Where to find medical care for hypopituitarism?

Directions to Hospitals Treating Hypopituitarism

Prevention

At present, there is no preventable measure for hypopituitarism.

What to expect (Outook/Prognosis)?

Prognosis of hypopituitarism depends on:

Copyleft Sources

http://www.mayoclinic.com/print/hypopituitarism/DS00479/DSECTION=all&METHOD=print

http://www.childrenshospital.org/az/Site1133/mainpageS1133P0.html

http://www.nlm.nih.gov/medlineplus/ency/article/000343.htm Template:WH Template:WS

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