Hyperkalemia resident survival guide: Difference between revisions

Jump to navigation Jump to search
No edit summary
No edit summary
Line 1: Line 1:
__NOTOC__
__NOTOC__
{{Hyperkalemia}}
{{CMG}}; {{AE}} {{Rim}}; {{MS}}
{{CMG}}; {{AE}} {{Rim}}; {{MS}}



Revision as of 16:33, 16 August 2013

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Rim Halaby, M.D. [2]; Mahmoud Sakr, M.D. [3]

Definition

Hyperkalemia is defined as a serum potassium concentration greater than 5.5 mEq/L in adults. Levels higher than 7 mEq/L can lead to significant hemodynamic compromise.

Causes

Life Threatening Causes

Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated.

Common Causes

Management

Shown below is an algorithm summarizing the approach to hyperkalemia.[1][2][3]

 
 
 
 
 
 
 
 
Potassium > 5.5 mEq/L
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
If repeated potassium level is normal, check potassium level in 24 hours
 
 
R/O Pseudohyperkalemia
(Artifact, hemolysis, elevated WBC, elevated RBC, elevated platelets)

Repeat potassium level
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Check vital signs
ABC's
Order an EKG
Obtain a concise history and physical exam
Order BUN, creatinine, glucose, ABG
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Assess EKG
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Presence of EKG changes
Loss of P waves, peaked T waves and wide QRS
 
 
 
 
 
 
 
 
 
Absence of EKG changes

and

Hemodynamically stable patient
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Do the following steps simultaneously:
1. Myocardial stabilization
IV Ca gluconate (1-2 amps)
Contraindicated in digoxin toxicity and hypercalcemia

2. Shift potassium from blood into cells
Insulin (0.2 units for every gram of glucose administered) and 20% dextrose ( 2.5-5 ml/kg/h)
Glucose level monitoring is needed

Beta2 agonists (albuterol is given 10-20mg via nebulizer or 0.5 mg IV)

3. Lower total body potassium
Cation exchange resin (kayexalate 30-90g given P.O. or P.R.)

Loop diuretics (furosemide 1-2 mg/kg)

Hemodialysis if refractory
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Potassium > 6 mEq/L
 
 
 
 
 
 
 
 
 
 
5.5mEq/L<Potassium<6mEq/L
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Do the following steps simultaneously:
1. Monitor for cardiac arrhythmia
Place the patient on a closely monitored bed for potential arrhythmias

2. Shift potassium from blood into cells
Insulin (0.2 units for every gram of glucose administered) and 20%dextrose ( 2.5-5 ml/kg/h)
Glucose level monitoring is needed

Beta2 agonists (albuterol is given 10-20mg via nebulizer or 0.5 mg IV)

3. Lower total body potassium
Cation exchange resin (kayexalate 30-90g given P.O. or P.R.
Loop diuretics (furosemide 1-2 mg/kg)

Hemodialysis if refractory
 
 
 
 
 
 
 
 
 
 
Lower total body potassium
Cation exchange resin (kayexalate 30-90g given P.O. or P.R.)

Loop diuretics (furosemide 1-2 mg/kg)
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
D/C any offending medications that is associated with hyperkalemia

D/C oral or parenteral potassium

Correct acidosis with bicarb if pH<7.2

Restrict dietary potassium intake

Review potassium levels every 2-4 hours until stabilized

Check levels of other electrolytes such as magnesium and phosphorus
 
 
 
 
 
 
 
 
 
 
 
 
 

References

  1. Lehnhardt A, Kemper MJ (2011). "Pathogenesis, diagnosis and management of hyperkalemia". Pediatr Nephrol. 26 (3): 377–84. doi:10.1007/s00467-010-1699-3. PMC 3061004. PMID 21181208.
  2. Ahee P. The management of hyperkalaemia in the emergency department. J Accid Emerg Med 2000;17:188-191 doi:10.1136/emj.17.3.18
  3. Weisberg L. Management of severe hyperkalemia. Crit Care Med 2008 Vol. 36, No. 12.


Template:WikiDoc Sources