Hairy cell leukemia diagnotic study of choice: Difference between revisions

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{{Hairy Cell Leukemia}}
{{Hairy cell leukemia}}  
{{CMG}}; {{AE}} {{VKG}}
{{CMG}}; {{AE}} {{VKG}}; {{GRR}} {{Nat}}
 
== Overview ==
== Overview ==
[[peripheral blood|Peripheral blood smears]] are the gold standard test for the diagnosis of [[hairy cell leukemia]].


== Diagnostic Study of Choice ==
== Diagnostic Study of Choice ==


=== Study of choice ===
=== Study of choice ===
[Name of the investigation] is the gold standard test for the diagnosis of [disease name].
OR
The following result of [gold standard test] is confirmatory of [disease name]:
* [Result 1]
* [Result 2]
OR
[Name of the investigation] must be performed when:
* The patient presents with [symptom/sign 1], [symptom/sign 2], and [symptom/sign 3].
* A [name of test] is positive for [sign 1], [sign 2], and [sign 3] in the patient.
OR
[Name of the investigation] is the gold standard test for the diagnosis of [disease name].
OR
The diagnostic study of choice for [disease name] is [name of the investigation].
OR
There is no single diagnostic study of choice for the diagnosis of [disease name].
OR


There is no single diagnostic study of choice for the diagnosis of [disease name], but [disease name] can be diagnosed based on [name of the investigation 1] and [name of the investigation 2].
==== Peripheral blood smear: ====
[[Peripheral blood smear|Peripheral blood smear]] is one of the gold standard tests for the diagnosis of [[hairy cell leukemia]].<ref name="pmid6505703">{{cite journal |vauthors=Burke JS, Rappaport H |title=The diagnosis and differential diagnosis of hairy cell leukemia in bone marrow and spleen |journal=Semin. Oncol. |volume=11 |issue=4 |pages=334–46 |date=December 1984 |pmid=6505703 |doi= |url=}}</ref>


OR
The following result of [[Peripheral blood smear|peripheral blood smears]] is confirmatory of [[hairy cell leukemia]]:
* Oval [[nuclei]] and abundant [[cytoplasm]] with "hairy" projections
* "Fried egg" appearance
* Loose [[chromatin]]
* [[Mast cells]] numbers elevate
* Extravasated red cells are positive in peripheral blood smear of [[hairy cell leukemia]] patients


[Disease name] is primarily diagnosed based on the clinical presentation.
== References ==
{{Reflist|2}}

Latest revision as of 17:24, 8 April 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Vamsikrishna Gunnam M.B.B.S [2]; Grammar Reviewer: Natalie Harpenau, B.S.[3]

Overview

Peripheral blood smears are the gold standard test for the diagnosis of hairy cell leukemia.

Diagnostic Study of Choice

Study of choice

Peripheral blood smear:

Peripheral blood smear is one of the gold standard tests for the diagnosis of hairy cell leukemia.[1]

The following result of peripheral blood smears is confirmatory of hairy cell leukemia:

References

  1. Burke JS, Rappaport H (December 1984). "The diagnosis and differential diagnosis of hairy cell leukemia in bone marrow and spleen". Semin. Oncol. 11 (4): 334–46. PMID 6505703.