Hairy cell leukemia epidemiology and demographics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2], James Nasr[3]; Grammar Reviewer: Natalie Harpenau, B.S.[4]
Overview
Hairy cell leukemia is relatively rare, accounting for 1.4% of all lymphomas. The incidence of hairy cell leukemia is approximately 2.8-3.0 per 1,000,000 individuals in the United States. The incidence of hairy cell leukemia increases with age. The median age range at diagnosis of hairy cell leukemia is 55 to 60 years. Males are more commonly affected with hairy cell leukemia than females. The male to female ratio is approximately 4 to 1.
Epidemiology and Demographics
Prevalence
- Hairy cell leukemia is considered one of the least common types of leukemias in the United States.
- Hairy cell leukemia accounts for 1.4% of all lymphomas. [1]
Incidence
- The incidence of hairy cell leukemia is approximately 2.8-3.0 per 1,000,000 individuals in the United States.[1]
- For the past 30 years, the incidence of hairy cell leukemia has been relatively constant.
Age
- The incidence of hairy cell leukemia increases with age.
- The median age range at diagnosis of hairy cell leukemia is 55 to 60 years.[2]
Gender
- Males are more commonly affected with hairy cell leukemia than females.
- The male to female ratio is approximately 4 to 1.[3]
Race
- Hairy cell leukemia usually affects individuals of European Ancestry.
- Asian and African American individuals are less likely to develop hairy cell leukemia.[4]
References
- ↑ 1.0 1.1 Teras LR, DeSantis CE, Cerhan JR, Morton LM, Jemal A, Flowers CR. 2016 US lymphoid malignancy statistics by World Health Organization subtypes. CA Cancer J Clin. 2016 Nov 12;66(6):443-459. doi: 10.3322/caac.21357. Epub 2016 Sep 12. PMID: 27618563.
- ↑ Epperla N, Zhao Q, Anghelina M, Neal J, Blachly JS, Rogers KA, Lozanski G, Oakes CC, Bhat SA, Zent CS, Banerji V, Grever M, Andritsos LA. Impact of sex on outcomes in patients with hairy cell leukemia. An HCL patient data registry analysis. Am J Hematol. 2023 May;98(5):E116-E118. doi: 10.1002/ajh.26881. Epub 2023 Feb 24. PMID: 36808760.
- ↑ Epperla N, Zhao Q, Anghelina M, Neal J, Blachly JS, Rogers KA, Lozanski G, Oakes CC, Bhat SA, Zent CS, Banerji V, Grever M, Andritsos LA. Impact of sex on outcomes in patients with hairy cell leukemia. An HCL patient data registry analysis. Am J Hematol. 2023 May;98(5):E116-E118. doi: 10.1002/ajh.26881. Epub 2023 Feb 24. PMID: 36808760.
- ↑ Tadmor T, Polliack A (December 2015). "Epidemiology and environmental risk in hairy cell leukemia". Best Pract Res Clin Haematol. 28 (4): 175–9. doi:10.1016/j.beha.2015.10.014. PMID 26614895.