Chronic renal failure risk factors: Difference between revisions
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==Risk factors== | ==Risk factors== | ||
===Age=== | ===Age=== | ||
* Age 65 or older | * Age 65 or older | ||
Revision as of 14:05, 24 November 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Aarti Narayan, M.B.B.S [2]
Overview
It is important to identify patients at risk for developing chronic renal disease, even in patients with a normal serum creatinine levels. Chronic renal failure, requiring dialysis or organ transplant, can often be prevented with early detection and treatment.
Risk factors
Age
- Age 65 or older
Race
- African-American or Hispanic race
Family history
- A positive family history
Comorbidities
- Diabetes
- Hypertension
- Autoimmune diseases including SLE, scleroderma, and polyarteritis nodosa
- Multiple myeloma
- Heart disease
- Smoking
- Obesity
- High cholesterol
Renal function
- Presence of proteinuria
- Abnormal urinary sediments
- Structural abnormalities of the urinary tract
- Past history of Acute renal failure
Genetics
- Certain DNA sequences like allelic versions of APOL1 gene (associated with West African ancestry), contribute to a several fold higher risk of some etiologies of Chronic renal failure e.g focal segmental glomerulosclerosis.