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==Overview==
==Overview==
'''Chronic renal failure''' (CRF), also known as '''chronic kidney failure''' (CKF) or '''chronic kidney disease''' (CKD), or '''chronic renal insufficiency''' (CRI) is a slowly progressive loss of [[renal function]] over a period of months or years, and defined as an abnormally low [[glomerular filtration rate]], which is usually determined indirectly by the [[creatinine]] level in blood serum.
'''Chronic renal failure''' (CRF), also known as '''chronic kidney failure''' (CKF) or '''chronic kidney disease''' (CKD), or '''chronic renal insufficiency''' (CRI) is a slowly progressive loss of [[renal function]] over a period of months or years defined as an abnormally low [[glomerular filtration rate]].  The glomerular filtration rate is usually determined indirectly by the [[creatinine]] level in blood serum.


CRF that leads to severe illness and requires some form of renal replacement therapy (such as [[dialysis]]) is called '''end-stage renal disease''' (ESRD).
CRF that leads to severe illness and requires some form of renal replacement therapy (such as [[dialysis]]) is called '''end-stage renal disease''' (ESRD).

Revision as of 14:04, 26 July 2012

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Aarti Narayan, M.B.B.S [2]

Overview

Chronic renal failure (CRF), also known as chronic kidney failure (CKF) or chronic kidney disease (CKD), or chronic renal insufficiency (CRI) is a slowly progressive loss of renal function over a period of months or years defined as an abnormally low glomerular filtration rate. The glomerular filtration rate is usually determined indirectly by the creatinine level in blood serum.

CRF that leads to severe illness and requires some form of renal replacement therapy (such as dialysis) is called end-stage renal disease (ESRD).

Pathophysiology

Epidemiology and Demographics

Risk Factors

Causes

Differentiating Chronic renal failure from other Conditions

Natural History, Complications and Prognosis

References


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