Bronchospasm

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Associate Editor(s)-in-Chief: Areej Tariq, Prashanth Saddala M.B.B.S.

Overview

Bronchospasm is a difficulty in breathing caused by a sudden constriction of the muscles in the walls of the bronchioles. It is caused by the release (degranulation) of substances from mast cells or basophils under the influence of anaphylatoxins.

Bronchospasm appears as the feature of asthma, chronic bronchitis, anaphylaxis, and as a possible side-effect of the drug Pilocarpine (which is used to treat illness resulting from the ingestion of deadly nightshade as well as other things). The overactivity of the bronchioles' muscle is a result of exposure to a stimulus which under normal circumstances would cause little or no response. The resulting constriction and inflammation causes a narrowing of the airways and an increase in mucous production; this reduces the amount of oxygen that is available to the individual causing breathlessness, coughing and hypoxia (that can cause cyanosis).

Causes

Common Causes

Causes by Organ System

Cardiovascular Churg-Strauss syndrome
Chemical / poisoning 5-Hydroxyindoleacetic acid, Alanycarb, Aldicarb, Aldoxycarb, Allyxycarb, Amidithion, Aminocarb, Amiton, Anaphylatoxin, Athyl-Gusathion, Azinfosethyl, Azinfos-methyl, Azinophos-methyl, Azinphos, Azinphos-ethyl, Azinphos-methyl, Azinphosmetile, Azothoate, Bendiocarb, Benfuracarb, Benoxafos, Bromophos, Bromophos-ethyl, Snake bite, Bufencarb, Butacarb, Butocarboxim, Butoxcarboxim, Cadusafos, Carbamates, Carbanolate, Carbaryl, Carbofuran, Carbophenothion, Carbosulfan, Caterpillar poisoning, Chlorfenvinphos, Chlorine Dioxide, Chloroacetophenone, Chlorobenzylidene Malononitrile, Chloropyrifos, Chlorpyrifos methyl, Cloethocarb, CS gas, Cyanthoate, Decarbofuran, Demeton, Demeton-methyl, Demeton-O, Demeton-O-methyl, Demeton-S-methyl, Demeton-S-methylsulphon, Dialifos, Diazinon, Dichlorvos, Dicresyl, Dicrotophos, Dimetan, Dimethoate, Dimetilan, Dioxacarb, Dioxathion, Disulfoton, EMPC, Endothion, Ethiofencarb, Ethion, Ethoate-methyl, Ethoprophos, Ethyl-guthion, Etrimfos, Eucalyptus oil , Fenchlorphos, Fenethacarb, Fenitrothion, Fenobucarb, Fensulfothion, Fenthion, Fonophos, Formothion, Furathiocarb, Gonionemus poisoning, Guthion (ethyl), Heptenophos, Hydrogen sulfide, Hyquincarb, Iodofenphos, Isofenphos, Isoprocarb, Latex allergy, Malathion, Mecarbam, Methacrifos, Methamidophos, Methidathion, Methiocarb, Methomyl, Methylene Diisocyanate, Metiltriazotion, Metolcarb, Mevinphos, Mexacarbate, Monocrotophos, Monosodium glutamate, Nitrilacarb, Nitrogen dioxide, Nitromethane, Omethoate, Organophosphates, Oxamyl, Oxydeprofos, Oxydisulfoton, Parathion, Parathion Methyl, Phenkapton, Phorate, Phosalone, Phosdrin, Phosmet, Phosphamidon, Phoxim, Pirimicarb, Pirimiphos-methyl, Platinum salts, Primiphos methyl, Profenofos, Promacyl, Promecarb, Propoxur, Prothidathion, Prothoate, Pyrimitate, Quinalphos, Quintiofos, Radiocontrast, Scombroid, Smoke inhalation, Sophamide, Sulfotep, Sulfur Trioxide, Tazimcarb, Terbufos, Tetraethyl Pyrophosphate, Tetrodotoxin, Thiocarboxime, Thiodicarb, Thiofanox, Thiometon, Tolclofos methyl, Toluene Diisocyanate, Triazophos, Triazotion, Trifenfos, Trimethacarb, Vamidothion, XMC, Xylylcarb, Analgesic asthma syndrome
Dermatologic No underlying causes
Drug Side Effect Abciximab, Acetylcysteine, Acetylsalicylic acid, Adenosine, Alemtuzumab, Aspirin, Atenolol, Atracurium, Benzonatate, Beta-blockers, Betahistine, Betaxolol, Bethanechol, Cocaine, Colistin, Cyclizine, Diclofenac, Felbinac, Hydroxyethyl starch, Ibritumomab tiuxetan, Ibuprofen, Indometacin, Ketamine, Ketorolac, Labetalol, Nadolol, Nitrazepam, NSAIDs, Penicillin, Pentamidine, Pilocarpine, Propafenone, Propranolol, Rapacuronium, Streptokinase, Timolol, Zanamivir
Ear Nose Throat No underlying causes
Endocrine Carcinoid syndrome
Environmental Byssinosis, Pollen allergy
Gastroenterologic No underlying causes
Genetic No underlying causes
Hematologic Hypereosinophilic syndrome, Mastocytosis
Iatrogenic Blood transfusion, Bronchial challenge test, Exercise stress testing
Infectious Disease Pfiesteria piscicida , Pneumonia, Schistosomiasis, Pulmonary eosinophilia, Pulmonary strongyloidiasis, Viral illness, Visceral larva migrans
Musculoskeletal / Ortho No underlying causes
Neurologic No underlying causes
Nutritional / Metabolic No underlying causes
Obstetric/Gynecologic No underlying causes
Oncologic Carcinoid tumour
Opthalmologic No underlying causes
Overdose / Toxicity Abciximab, Acetylcysteine, Acetylsalicylic acid, Adenosine, Alemtuzumab, Aspirin, Atenolol, Atracurium, Benzonatate, Beta-blockers, Betahistine, Betaxolol, Bethanechol, Cocaine, Colistin, Cyclizine, Diclofenac, Felbinac, Hydroxyethyl starch, Ibritumomab tiuxetan, Ibuprofen, Indometacin, Ketamine, Ketorolac, Labetalol, Nadolol, Nitrazepam, NSAIDs, Penicillin, Pentamidine, Pilocarpine, Propafenone, Propranolol, Rapacuronium, Streptokinase, Timolol, Zanamivir
Psychiatric No underlying causes
Pulmonary Shaver's disease, Allergic bronchopulmonary aspergillosis, Asthma, Bronchiolitis, Bronchopulmonary dysplasia, Emphysema
Renal / Electrolyte No underlying causes
Rheum / Immune / Allergy No underlying causes
Sexual No underlying causes
Trauma No underlying causes
Urologic No underlying causes
Dental No underlying causes
Miscellaneous Anaphylaxis, Anaphylactic shock, Aspiration, Exercise induced bronchospasm, Food allergy, Clove cigarette smoking, Near-drowning, Peanut allergies

Causes in Alphabetical Order


References


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